Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Dmitry Filimonov"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/9130372a7d624bb288bbb322ef46ae85
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2447-2459 (2021)
Cytotoxic and noncytotoxic CD8+ T lymphocyte responses are essential for the control of HIV infection. Understanding the mechanisms underlying HIV control in elite controllers (ECs), which maintain undetectable viral load in the absence of antiretrov
Externí odkaz:
https://doaj.org/article/f0be923293074d34adddea355ffcc0ef
Autor:
Olga Tarasova, Nadezhda Biziukova, Andrey Shemshura, Dmitry Filimonov, Dmitry Kireev, Anastasia Pokrovskaya, Vladimir V. Poroikov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1465 (2023)
Viruses cause various infections that may affect human lifestyle for durations ranging from several days to for many years. Although preventative and therapeutic remedies are available for many viruses, they may still have a profound impact on human
Externí odkaz:
https://doaj.org/article/a3b3303223f94003b0791c1defa3dd66
Publikováno v:
Molecules, Vol 27, Iss 18, p 5875 (2022)
Human cytochrome P450 enzymes (CYPs) are heme-containing monooxygenases. This superfamily of drug-metabolizing enzymes is responsible for the metabolism of most drugs and other xenobiotics. The inhibition of CYPs may lead to drug–drug interactions
Externí odkaz:
https://doaj.org/article/1a6220d420be4d47b59682ba314b2c91
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The interaction of human immunodeficiency virus with human cells is responsible for all stages of the viral life cycle, from the infection of CD4+ cells to reverse transcription, integration, and the assembly of new viral particles. To date, a large
Externí odkaz:
https://doaj.org/article/6dde30fed07640d7b03873bc05a79afc
Autor:
Robin P. Forslund, William G. Hardin, Xi Rong, Artem M. Abakumov, Dmitry Filimonov, Caleb T. Alexander, J. Tyler Mefford, Hrishikesh Iyer, Alexie M. Kolpak, Keith P. Johnston, Keith J. Stevenson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Water electrolysis provides a potential means to large-scale renewable fuel generation, although sluggish oxygen evolution kinetics challenges progress. Here, authors report on Ruddlesden–Popper oxides as active oxygen evolution electrocatalysts th
Externí odkaz:
https://doaj.org/article/7bddd8ca046341fdbedcd5afbae8c6cd
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 7, p e1006851 (2019)
Adverse drug effects (ADEs) are one of the leading causes of death in developed countries and are the main reason for drug recalls from the market, whereas the ADEs that are associated with action on the cardiovascular system are the most dangerous a
Externí odkaz:
https://doaj.org/article/71921499dd3746d9972d2e56ef5c52a7
Prediction of Protein–ligand Interaction Based on Sequence Similarity and Ligand Structural Features
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8152 (2020)
Computationally predicting the interaction of proteins and ligands presents three main directions: the search of new target proteins for ligands, the search of new ligands for targets, and predicting the interaction of new proteins and new ligands. W
Externí odkaz:
https://doaj.org/article/f95db19f9f5d4dc1bcc09013f979fe0a
Autor:
Olga Tarasova, Nadezhda Biziukova, Dmitry Kireev, Alexey Lagunin, Sergey Ivanov, Dmitry Filimonov, Vladimir Poroikov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 748 (2020)
Human Immunodeficiency Virus Type 1 (HIV-1) infection is associated with high mortality if no therapy is provided. Currently, the treatment of an HIV-1 positive patient requires that several drugs should be taken simultaneously. The resistance of the
Externí odkaz:
https://doaj.org/article/21003c40a3094c08857fc243d6c276f4
Autor:
Alexander Dmitriev, Dmitry Filimonov, Alexey Lagunin, Dmitry Karasev, Pavel Pogodin, Anastasiya Rudik, Vladimir Poroikov
Publikováno v:
Molecules, Vol 24, Iss 21, p 3955 (2019)
Drug-drug interactions (DDIs) severity assessment is a crucial problem because polypharmacy is increasingly common in modern medical practice. Many DDIs are caused by alterations of the plasma concentrations of one drug due to another drug inhibiting
Externí odkaz:
https://doaj.org/article/e1e91bccf6e24c32be87ddd2d9fc62c7