Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dmitry E Andreev"'
Autor:
Dmitry E Andreev, Maxim Arnold, Stephen J Kiniry, Gary Loughran, Audrey M Michel, Dmitrii Rachinskii, Pavel V Baranov
Publikováno v:
eLife, Vol 7 (2018)
Translation initiation is the rate-limiting step of protein synthesis that is downregulated during the Integrated Stress Response (ISR). Previously, we demonstrated that most human mRNAs that are resistant to this inhibition possess translated upstre
Externí odkaz:
https://doaj.org/article/37d6e8bce4cc4482ab33c3de14246b98
Autor:
Dmitry E Andreev, Patrick BF O'Connor, Ciara Fahey, Elaine M Kenny, Ilya M Terenin, Sergey E Dmitriev, Paul Cormican, Derek W Morris, Ivan N Shatsky, Pavel V Baranov
Publikováno v:
eLife, Vol 4 (2015)
Eukaryotic cells rapidly reduce protein synthesis in response to various stress conditions. This can be achieved by the phosphorylation-mediated inactivation of a key translation initiation factor, eukaryotic initiation factor 2 (eIF2). However, the
Externí odkaz:
https://doaj.org/article/c2d8cbe5bef34a56b73eba6e7bcc0dae
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract The synthesis of most proteins begins at AUG codons, yet a small number of non-AUG initiated proteoforms are also known. Here we analyse a large number of publicly available Ribo-seq datasets to identify novel, previously uncharacterised non
Externí odkaz:
https://doaj.org/article/14d6f587a3ea4037a0db7d86278ff798
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5270963e2d764e298a6b93db10594636
Autor:
Oro Uchenunu, Alexander V. Zhdanov, Phillipe Hutton, Predrag Jovanovic, Ye Wang, Dmitry E. Andreev, Laura Hulea, David J. Papadopoli, Daina Avizonis, Pavel V. Baranov, Michael N. Pollak, Dmitri B. Papkovsky, Ivan Topisirovic
Publikováno v:
FEBS Open Bio, Vol 12, Iss 5, Pp 959-982 (2022)
Mutations in genes encoding cytochrome c oxidase (mitochondrial complex IV) subunits and assembly factors [e.g., synthesis of cytochrome c oxidase 2 (SCO2)] are linked to severe metabolic syndromes. Notwithstanding that SCO2 is under transcriptional
Externí odkaz:
https://doaj.org/article/f8fde63c9e464bee9765b343a923087e
Autor:
Dmitry E. Andreev, Gary Loughran, Alla D. Fedorova, Maria S. Mikhaylova, Ivan N. Shatsky, Pavel V. Baranov
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Recent proteogenomic studies revealed extensive translation outside of annotated protein coding regions, such as non-coding RNAs and untranslated regions of mRNAs. This non-canonical translation is largely due to start codon plurality within
Externí odkaz:
https://doaj.org/article/29b0c5b7edd04b93a58129c5788f35cd
Autor:
Desislava S. Makeeva, Andrey S. Lando, Aleksandra Anisimova, Artyom A. Egorov, Maria D. Logacheva, Alexey A. Penin, Dmitry E. Andreev, Pavel G. Sinitcyn, Ilya M. Terenin, Ivan N. Shatsky, Ivan V. Kulakovskiy, Sergey E. Dmitriev
Publikováno v:
Data in Brief, Vol 23, Iss , Pp - (2019)
TMA20 (MCT-1), TMA22 (DENR) and TMA64 (eIF2D) are eukaryotic translation factors involved in ribosome recycling and re-initiation. They operate with P-site bound tRNA in post-termination or (re-)initiation translation complexes, thus participating in
Externí odkaz:
https://doaj.org/article/2053cfc135094bb9a3421889f4a2dbdf
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Ribosome profiling data can suffer from uneven coverage which hampers estimation of elongation rates. Connor et al.present an enhanced data smoothing method for Ribo-seq data and highlight significant variability in sequence determinants of ribosome
Externí odkaz:
https://doaj.org/article/42f88ac9182b471484c206f16074bb5e
Publikováno v:
International journal of molecular sciences. 23(24)
The phenomenon of internal initiation of translation was discovered in 1988 on poliovirus mRNA. The prototypic cis-acting element in the 5′ untranslated region (5′UTR) of poliovirus mRNA, which is able to direct initiation at an internal start co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40daef107abfbcadd067b99ee17a3ddb
https://pubmed.ncbi.nlm.nih.gov/36555135
https://pubmed.ncbi.nlm.nih.gov/36555135
Publikováno v:
Biochemistry (Moscow). 86:1095-1106
Ribosome profiling (riboseq) has opened the possibilities for the genome-wide studies of translation in all living organisms. This method is based on deep sequencing of mRNA fragments protected by the ribosomes from hydrolysis by ribonucleases, the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028ef338acfb829b421ed8e201e2d645
https://doi.org/10.1134/s0006297921090054
https://doi.org/10.1134/s0006297921090054