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Autor:
Ilya I. Afanasyev, Valery S. Kochubey, Natalya I. Vasilevich, Dmitry A. Kovalskiy, Dmitry V. Genis
Publikováno v:
Chemical biologydrug design. 84(5)
The general model of epitope-type MDM2 inhibitor was developed based on the structural information on the complexes between MDM2 and various low molecular weight ligands found in the PDB database. Application of this model to our in-house library has