Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Dmitry A. Knorre"'
Publikováno v:
Biology, Vol 13, Iss 11, p 927 (2024)
Unlike most animals, some fungi, including baker’s yeast, inherit mitochondrial DNA (mtDNA) from both parents. When haploid yeast cells fuse, they form a heteroplasmic zygote, whose offspring retain one or the other variant of mtDNA. Meanwhile, som
Externí odkaz:
https://doaj.org/article/2134aee050a84b109f7f499121cf0c69
Autor:
Victor Shamanskiy, Alina A. Mikhailova, Evgenii O. Tretiakov, Kristina Ushakova, Alina G. Mikhailova, Sergei Oreshkov, Dmitry A. Knorre, Natalia Ree, Jonathan B. Overdevest, Samuel W. Lukowski, Irina Gostimskaya, Valerian Yurov, Chia-Wei Liou, Tsu-Kung Lin, Wolfram S. Kunz, Alexandre Reymond, Ilya Mazunin, Georgii A. Bazykin, Jacques Fellay, Masashi Tanaka, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Aging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Such deletions are often flanked by direct nucleotide repeats, but this alone does no
Externí odkaz:
https://doaj.org/article/4165b20a8937424aafa2ba2a950a3360
Mitochondrial heteroplasmy as a cause of cell-to-cell phenotypic heterogeneity in clonal populations
Autor:
Dmitry A. Knorre
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/425e388733b440b6990e988f61f7e2ce
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
In yeast, multiple (pleiotropic) drug resistance (MDR) transporters efflux xenobiotics from the cytoplasm to the environment. Additionally, upon the accumulation of xenobiotics in the cells, MDR genes are induced. At the same time, fungal cells can p
Externí odkaz:
https://doaj.org/article/d23b98127ce944068e18eae56b942484
Autor:
Kseniia V. Galkina, Valeria M. Zubareva, Nataliia D. Kashko, Anna S. Lapashina, Olga V. Markova, Boris A. Feniouk, Dmitry A. Knorre
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
In mitochondria, a small protein IF1 suppresses the hydrolytic activity of ATP synthase and presumably prevents excessive ATP hydrolysis under conditions of energy deprivation. In yeast Saccharomyces cerevisiae, IF1 homologs are encoded by two paralo
Externí odkaz:
https://doaj.org/article/b4496a278e6f4c2791ee0ee4fef800bc
Autor:
Svyatoslav S. Sokolov, Marina M. Popova, Peter Pohl, Andreas Horner, Sergey A. Akimov, Natalia A. Kireeva, Dmitry A. Knorre, Oleg V. Batishchev, Fedor F. Severin
Publikováno v:
Membranes, Vol 12, Iss 12, p 1278 (2022)
Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol
Externí odkaz:
https://doaj.org/article/0c78cdd056db4d9fae5e6bc35eea38ec
Autor:
Svyatoslav S. Sokolov, Margarita A. Vorobeva, Alexandra I. Smirnova, Ekaterina A. Smirnova, Nataliya I. Trushina, Kseniia V. Galkina, Fedor F. Severin, Dmitry A. Knorre
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs. Because the function of paralogous genes can be redundant, the phenotypes o
Externí odkaz:
https://doaj.org/article/054f6e9e2d3845c194739cf233fe43cb
Publikováno v:
Microbial Cell, Vol 3, Iss 11, Pp 532-539 (2016)
Apart from energy transformation, mitochondria play important signaling roles. In yeast, mitochondrial signaling relies on several molecular cascades. However, it is not clear how a cell detects a particular mitochondrial malfunction. The problem is
Externí odkaz:
https://doaj.org/article/418c1ef2964f4e69ba03bd07ac0ec4f0
Autor:
Svyatoslav S. Sokolov, Ekaterina A. Smirnova, Olga V. Markova, Natalya A. Kireeva, Roman S. Kirsanov, Liudmila S. Khailova, Dmitry A. Knorre, Fedor F. Severin
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1345 (2020)
Chemicals inducing a mild decrease in the ATP/ADP ratio are considered as caloric restriction mimetics as well as treatments against obesity. Screening for such chemicals in animal model systems requires a lot of time and labor. Here, we present a sy
Externí odkaz:
https://doaj.org/article/2521315c69294ff69757321505e036f1
Publikováno v:
Microbial Cell, Vol 1, Iss 1, Pp 37-42 (2014)
The yeast Saccharomyces cerevisiae is successfully used as a model organism to find genes responsible for lifespan control of higher organisms. As functional decline of higher eukaryotes can start as early as one quarter of the average lifespan, we a
Externí odkaz:
https://doaj.org/article/1eb1582c0ce8462ca68f3649fbd39e8b