Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dmitriy W Gutkin"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56886 (2013)
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects
Externí odkaz:
https://doaj.org/article/a359b9eee8934eb7b63ed93c687571f3
Autor:
Denise Prosser, Esther Elishaev, Mounia Alaoui El Azher, Liudmila Velikokhatnaya, Paul M. Stemmer, Namhee Shin, Francesmary Modugno, Anna Lokshin, Dmitriy W. Gutkin, Galina V. Shurin, Michael R. Shurin
Publikováno v:
Cancer Biomarkers. 26:471-479
Ovarian cancer is the leading cause of death among gynecologic diseases in the USA and Europe. High-grade serous carcinoma (HGSC) of the ovary, the most aggressive type of ovarian cancer, is typically diagnosed at advanced stages when the 5-year surv
Autor:
Timur O. Khaliullin, Michael R. Shurin, Valerian E. Kagan, Naveena Yanamala, Ashley R. Murray, Elena R. Kisin, Liliya M. Fatkhutdinova, Anna A. Shvedova, Dmitriy W. Gutkin
Publikováno v:
Experimental Lung Research. 43:311-326
PURPOSE OF THE STUDY: A number of in vivo studies have shown that pulmonary exposure to carbon nanotubes (CNTs) may lead to an acute local inflammatory response, pulmonary fibrosis, and granulomatous lesions. Among the factors that play direct roles
Autor:
Maciej Pietrzak, Pawel Muranski, Lauren M. Browning, Dustin J. Lowery, Dmitriy W. Gutkin, Agnieszka Kurczewska, Justin M. Refugia, Michal Kuczma, Piotr Kraj, Grzegorz A. Rempala, Colin Simms, Leszek Ignatowicz
Publikováno v:
Science Signaling. 11
The cytokines of the transforming growth factor–β (TGF-β) family promote the growth and differentiation of multiple tissues, but the role of only the founding member, TGF-β, in regulating the immune responses has been extensively studied. TGF-β
Autor:
Dmitriy W. Gutkin, Galina V. Shurin, Naveena Yanamala, Alexander Star, Anna A. Shvedova, Elena R. Kisin, Alexey V. Tkach, Michael R. Shurin, Valerian E. Kagan
Publikováno v:
Cancer Research. 75:1615-1623
During the last decades, changes have been observed in the frequency of different histologic subtypes of lung cancer, one of the most common causes of morbidity and mortality, with a declining proportion of squamous cell carcinomas and an increasing
Autor:
Naveena Yanamala, Aleksandar D. Bugarski, Valerian E. Kagan, Anna A. Shvedova, Mariana T. Farcas, Elena R. Kisin, Dmitriy W. Gutkin, Michael R. Shurin
Publikováno v:
Environmental and Molecular Mutagenesis. 56:265-276
Altering the fuel source from petroleum-based ultra-low sulfur diesel to biodiesel and its blends is considered by many to be a sustainable choice for controlling exposures to particulate material. As the exhaust of biodiesel/diesel blends is compose
Autor:
Hua Zhong, Dmitriy W. Gutkin, Anton A. Keskinov, Galina V. Shurin, Yang Ma, Michael R. Shurin, Baohui Han
Publikováno v:
International Journal of Cancer. 134:2633-2645
Protumorigenic activity of immune regulatory cells has been proven to play a major role in precluding immunosurveillance and limiting the efficacy of anticancer therapies. Although several approaches have been offered to deplete myeloid-derived suppr
Autor:
Dmitriy W. Gutkin, Autumn L. Menas, Alexander Star, Kai Savolainen, Elena R. Kisin, Naveena Yanamala, Richard S. Reiner, Mariana T. Farcas, Anna A. Shvedova
Publikováno v:
Journal of toxicology and environmental health. Part A. 79(21)
Over the past several years there has been an increased number of applications of cellulosic materials in many sectors, including the food industry, cosmetics, and pharmaceuticals. However, to date, there are few studies investigating the potential a
Autor:
Olivera J. Finn, Dmitriy W. Gutkin, Pamela L. Beatty, Randall E. Brand, Rick van der Geest, Jana G. Hashash, Takashi Kimura
Publikováno v:
Cancer immunology, immunotherapy : CII. 65(7)
Premalignant lesions for many cancers have been identified, and efforts are currently directed toward identification of antigens expressed on these lesions that would provide suitable targets for vaccines for cancer prevention. Intraductal papillary