Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dmitriy G, Bobrovnikov"'
Autor:
Shaopeng Wang, Malgorzata J. Latallo, Zhe Zhang, Bo Huang, Dmitriy G. Bobrovnikov, Daoyuan Dong, Nathan M. Livingston, Wilson Tjoeng, Lindsey R. Hayes, Jeffrey D. Rothstein, Lyle W. Ostrow, Bin Wu, Shuying Sun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Hexanucleotide repeat expansion in the intron 1 of the C9ORF72 gene can cause amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Here the authors use single molecule imaging to show nuclear export and translation of circular rep
Externí odkaz:
https://doaj.org/article/fa693cbc636a4db9b4b2a4b8bdc7fe5c
Autor:
Aakash Basu, Dmitriy G. Bobrovnikov, Basilio Cieza, Juan Pablo Arcon, Zan Qureshi, Modesto Orozco, Taekjip Ha
Publikováno v:
Nat Struct Mol Biol
Diverse DNA-deforming processes are impacted by the local mechanical and structural properties of DNA, which in turn depend on local sequence and epigenetic modifications. Deciphering this mechanical code (that is, this dependence) has been challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75249e40b1589b10cae49c518c0e67b
https://europepmc.org/articles/PMC10142808/
https://europepmc.org/articles/PMC10142808/
Autor:
H. Tomas Rube, Zan Qureshi, Tunc Kayikcioglu, Cynthia Wolberger, Sebastian Eustermann, Miroslav Hejna, Jun S. Song, Taekjip Ha, Aakash Basu, Thuy T.M. Ngo, Dmitriy G. Bobrovnikov, Basilio Cieza, Karl-Peter Hopfner, Michael T. Morgan, Anand Ranjan
Publikováno v:
Nature
Mechanical deformations of DNA such as bending are ubiquitous and have been implicated in diverse cellular functions1. However, the lack of high-throughput tools to measure the mechanical properties of DNA has limited our understanding of how DNA mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c470362aa99a366579071c55403ba99
Publikováno v:
Journal of molecular biology. 433(6)
Almost all nucleoprotein interactions and DNA manipulation events involve mechanical deformations of DNA. Extraordinary progresses in single-molecule, structural, and computational methods have characterized the average mechanical properties of DNA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f0cdce3cb4dba76063dc83628b962e
https://pubmed.ncbi.nlm.nih.gov/33539885
https://pubmed.ncbi.nlm.nih.gov/33539885
Sequence features have long been known to influence the local mechanical properties and shapes of DNA. However, a mechanical code (i.e. a comprehensive mapping between DNA sequence and mechanical properties), if it exists, has been difficult to exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5efabf7e12f38ba6721dea52adebe6c3
https://doi.org/10.1101/2020.08.22.262352
https://doi.org/10.1101/2020.08.22.262352
Autor:
Dmitriy G. Bobrovnikov, Jeffrey D. Rothstein, Bin Wu, Lyle W. Ostrow, Zhe Zhang, Wilson Tjoeng, Nathan M. Livingston, Shuying Sun, Lindsey R. Hayes, Bo Huang, Daoyuan Dong, Shaopeng Wang, Malgorzata J. Latallo
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
C9ORF72 hexanucleotide GGGGCC repeat expansion is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Repeat-containing RNA mediates toxicity through nuclear granules and dipeptide repeat (DPR) prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b3437ee3526931b95ca82ed90e018f
https://pubmed.ncbi.nlm.nih.gov/34389711
https://pubmed.ncbi.nlm.nih.gov/34389711
Autor:
Karl-Peter Hopfner, Aakash Basu, Zan Qureshi, Taekjip Ha, Miroslav Hejna, Tunc Kayikcioglu, Cynthia Wolberger, H. Tomas Rube, Thuy T.M. Ngo, Dmitriy G. Bobrovnikov, Sebastian Eustermann, Michael T. Morgan, Basilio Cieza, Anand Ranjan, Jun S. Song
Mechanical deformations of DNA such as bending are ubiquitous and implicated in diverse cellular functions1. However, the lack of high-throughput tools to directly measure the mechanical properties of DNA limits our understanding of whether and how D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d03e03ead39ee55530e12bb9ae5c484
https://doi.org/10.1101/2020.08.17.255042
https://doi.org/10.1101/2020.08.17.255042
Autor:
Aakash, Basu, Dmitriy G, Bobrovnikov, Zan, Qureshi, Tunc, Kayikcioglu, Thuy T M, Ngo, Anand, Ranjan, Sebastian, Eustermann, Basilio, Cieza, Michael T, Morgan, Miroslav, Hejna, H Tomas, Rube, Karl-Peter, Hopfner, Cynthia, Wolberger, Jun S, Song, Taekjip, Ha
Publikováno v:
Nature. 589(7842)
Mechanical deformations of DNA such as bending are ubiquitous and have been implicated in diverse cellular functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fb1c0dd261dd65f9ed547c9e3e96044
https://pubmed.ncbi.nlm.nih.gov/33858745
https://pubmed.ncbi.nlm.nih.gov/33858745
Autor:
Malgorzata J. Latallo, Shaopeng Wang, Zhe Zhang, Bo Huang, Dmitriy G. Bobrovnikov, Daoyuan Dong, Nathan M. Livingston, Wilson Tjoeng, Lindsey R. Hayes, Jeffrey D. Rothstein, Lyle W. Ostrow, Bin Wu, Shuying Sun
Publikováno v:
Biophysical Journal. 121:311a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd1bd0c81b7bf6af4a17543bf2f0a00
https://doi.org/10.1016/j.bpj.2021.11.1201
https://doi.org/10.1016/j.bpj.2021.11.1201
Publikováno v:
Biophysical Journal. 116:76a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba65d8911c1015dd387f991f2fd2b9fa
https://doi.org/10.1016/j.bpj.2018.11.449
https://doi.org/10.1016/j.bpj.2018.11.449