Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dmitriy A. Khodakov"'
Publikováno v:
Nature Biomedical Engineering. 5:702-712
Assays for the molecular detection of nucleic acids are typically constrained by the level of multiplexing (this is the case for the quantitative polymerase chain reaction (qPCR) and for isothermal amplification), turnaround times (as with microarray
Publikováno v:
Materials Horizons. 8:1304-1313
This work demonstrates a simple dual-well device which enables spatially isolated solutions to undergo complementary redox reactions. The device functions by the ambipolar transport of charge carriers between two spatially isolated poly(dimethylsilox
Publikováno v:
ACS Sens
Concentrations of different nucleic acid species in biological samples span many orders of magnitude. A real-time polymerase chain reaction maps the concentration of a target nucleic acid sequence log-linearly into cycle threshold to enable quantitat
Current platforms for molecular analysis of DNA markers are either limited in multiplexing (qPCR, isothermal amplification), turnaround time (microarrays, NGS), quantitation accuracy (isothermal amplification, microarray, nanopore sequencing), or spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d74e88369ee08a560203d1fc7b9d16
Diagnostics based on nucleic acid sequence variant profiling: PCR, hybridization, and NGS approaches
Publikováno v:
Advanced Drug Delivery Reviews. 105:3-19
Nucleic acid sequence variations have been implicated in many diseases, and reliable detection and quantitation of DNA/RNA biomarkers can inform effective therapeutic action, enabling precision medicine. Nucleic acid analysis technologies being trans
Autor:
Sophie C. Leterme, Amanda V. Ellis, Dmitriy A. Khodakov, Sergio Balzano, Tamar Jamieson, Deevesh A. Hemraj
Publikováno v:
Environmental Science: Water Research & Technology. 2:376-382
Open Access Article. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Biofouling of seawater reverse osmosis (SWRO) membranes represents one of the leading causes of performance deterioration in the desalinatio
Biofouling of seawater reverse osmosis (SWRO) membranes represents one of the leading causes of performance deterioration in the desalinatio
Autor:
Amanda V. Ellis, Natalya M. Schmerl, Andrew J. Stapleton, Gunther G. Andersson, Dmitriy A. Khodakov
Publikováno v:
Applied Surface Science. 353:693-699
The use of polydimethylsiloxane (PDMS) is increasing with new technologies working toward compact, flexible and transparent devices for use in medical and microfluidic systems. Electronic characterization of PDMS and other insulating materials is dif
Autor:
Amanda V. Ellis, Dmitriy A. Khodakov
Publikováno v:
Microchimica Acta. 181:1633-1646
This review (containing 101 refs.) covers recent achievements in the development of new approaches for enzymatically assisted detection of nucleic acids on microarrays. We discuss molecular techniques including the polymerase chain reaction, reverse
Publikováno v:
Journal of the American Chemical Society. 135:5612-5619
Toehold-mediated DNA strand displacement provides unique advantages in the construction and manipulation of multidimensional DNA nanostructures as well as nucleic acid sequence analysis. We demonstrate a step change in the use of toehold-mediated DNA
Autor:
Jason F. Alvino, Robert G. Acres, Claire E. Lenahan, Gunther G. Andersson, Dmitriy A. Khodakov, Amanda V. Ellis, Gregory F. Metha
Publikováno v:
The Journal of Physical Chemistry C. 116:6289-6297
The use of the coupling agent, 3-aminopropyltriethoxysilane (APTES), in the silanization reaction with silanol-terminated silicon is an important surface modification reaction. Of particular importance is that the terminal amine functionalities of AP