Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Dmitri V Gordienko"'
Autor:
Valerio Farfariello, Dmitri V. Gordienko, Lina Mesilmany, Yasmine Touil, Emmanuelle Germain, Ingrid Fliniaux, Emilie Desruelles, Dimitra Gkika, Morad Roudbaraki, George Shapovalov, Lucile Noyer, Mathilde Lebas, Laurent Allart, Nathalie Zienthal-Gelus, Oksana Iamshanova, Franck Bonardi, Martin Figeac, William Laine, Jerome Kluza, Philippe Marchetti, Bruno Quesnel, Daniel Metzger, David Bernard, Jan B. Parys, Loïc Lemonnier, Natalia Prevarskaya
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Mitochondrial Ca2+ homeostasis is reported to influence cellular senescence. Here the authors show that TRPC3 limits senescence by inhibiting IP3R-mediated Ca2+ release and ER mitochondria Ca2+ transfer and that the downregulation of TRPC3 in stromal
Externí odkaz:
https://doaj.org/article/18e1a197a54f4fbebb56df91fdd44151
Publikováno v:
International Review of Cell and Molecular Biology ISBN: 9780128240366
In recent decades cancer emerged as one of the leading causes of death in the developed countries, with some types of cancer contributing to the top 10 causes of death on the list of the World Health Organization. Carcinogenesis, a malignant transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5188a80f63c593e0c0d2a2cedea169
https://doi.org/10.1016/bs.ircmb.2021.02.016
https://doi.org/10.1016/bs.ircmb.2021.02.016
Autor:
V'yacheslav Lehen'kyi, Maylis Raphaël, Agathe Oulidi, Matthieu Flourakis, Sergii Khalimonchyk, Artem Kondratskyi, Dmitri V Gordienko, Brigitte Mauroy, Jean-Lois Bonnal, Roman Skryma, Natalia Prevarskaya
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16856 (2011)
Despite remarkable advances in the therapy and prevention of prostate cancer it is still the second cause of death from cancer in industrialized countries. Many therapies initially shown to be beneficial for the patients were abandoned due to the hig
Externí odkaz:
https://doaj.org/article/179e9fe891d94c3cb6e0b525824e4109
Autor:
Valerio, Farfariello, Dmitri V, Gordienko, Lina, Mesilmany, Yasmine, Touil, Emmanuelle, Germain, Ingrid, Fliniaux, Emilie, Desruelles, Dimitra, Gkika, Morad, Roudbaraki, George, Shapovalov, Lucile, Noyer, Mathilde, Lebas, Laurent, Allart, Nathalie, Zienthal-Gelus, Oksana, Iamshanova, Franck, Bonardi, Martin, Figeac, William, Laine, Jerome, Kluza, Philippe, Marchetti, Bruno, Quesnel, Daniel, Metzger, David, Bernard, Jan B, Parys, Loïc, Lemonnier, Natalia, Prevarskaya
Publikováno v:
Nature communications. 13(1)
Cellular senescence is implicated in a great number of diseases including cancer. Although alterations in mitochondrial metabolism were reported as senescence drivers, the underlying mechanisms remain elusive. We report the mechanism altering mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e86e0c9b882f6fc6ce276d5223315fa2
https://pubmed.ncbi.nlm.nih.gov/35177596
https://pubmed.ncbi.nlm.nih.gov/35177596
Autor:
Laurent Héliot, Christian Slomianny, Oksana Iamshanova, Dimitra Gkika, Valerio Farfariello, Maxime Guéguinou, Roseline Guibon, Yves Gouriou, Etienne Dewailly, Melanie Paillard, Loic Lemonnier, Gaëlle Fromont, Pilar López-Alvarado, Dmitri V. Gordienko, Christophe Chouabe, J. Carlos Menéndez, Natalia Prevarskaya, Gabriel Bidaux, George Shapovalov, Anne-Sophie Borowiec
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2018, 1865 (7), pp.981-994. ⟨10.1016/j.bbamcr.2018.04.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2018, 1865 (7), pp.981-994. ⟨10.1016/j.bbamcr.2018.04.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2018, 1865 (7), pp.981-994. ⟨10.1016/j.bbamcr.2018.04.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2018, 1865 (7), pp.981-994. ⟨10.1016/j.bbamcr.2018.04.007⟩
International audience; Calcium (Ca2+) release from the endoplasmic reticulum plays an important role in many cell-fate defining cellular processes. Traditionally, this Ca2+ release was associated with the ER Ca2+ release channels, inositol 1,4,5-tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23264ad02d72db0952b74f1f1736c01
https://hal.archives-ouvertes.fr/hal-01847399
https://hal.archives-ouvertes.fr/hal-01847399
Publikováno v:
Pharmacological Reports. 67:1055-1060
Background Purinergic P2X receptors in vascular smooth muscle cells (VSMCs) play an important role in physiological stimulatory responses to the extracellularly released ATP. The aim of this work was to identify molecular P2X receptor subunits in VSM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7d277f4adc255af776342976819b1d
https://doi.org/10.1016/j.pharep.2015.03.014
https://doi.org/10.1016/j.pharep.2015.03.014
Autor:
Etienne Dewailly, Fabien Vanden Abeele, Dmitri V. Gordienko, Natalia Prevarskaya, Robert-Allain Toillon, Philippe Delcourt, Kateryna Kondratska, Christian Slomianny, Roman Skryma, Christophe Biot, Sébastien Lemière, Charlotte Dubois, Artem Kondratskyi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Despite the tremendous progress in medicine, cancer remains one of the most serious global health problems awaiting new effective therapies. Here we present ferroquine (FQ), the next generation antimalarial drug, as a promising candidate for repositi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b53c3d41aa6d3b0d9cd65614ba5ca1
https://doi.org/10.1038/s41598-017-16154-2
https://doi.org/10.1038/s41598-017-16154-2
Autor:
Christian Slomianny, George Shapovalov, Geert Bultynck, Roman Skryma, Anne-Sophie Borowiec, Dmitri V. Gordienko, Gabriel Bidaux, Natalia Prevarskaya, Abigael Ritaine
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, 2017, 7, pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, 2017, 7, pp.14082. ⟨10.1038/s41598-017-13968-y⟩
Intracellular ion channels are involved in multiple signaling processes, including such crucial ones as regulation of cellular motility and fate. With 95% of the cellular membrane belonging to intracellular organelles, it is hard to overestimate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10853383ab401064bda5f13b4f4817d
https://hal.archives-ouvertes.fr/hal-03060362/document
https://hal.archives-ouvertes.fr/hal-03060362/document
Publikováno v:
Neurophysiology. 46:398-404
Ionotropic P2X receptors (P2XRs) are involved in sympathetic control of the vascular tone; they mediate entry of Ca2+ in smooth muscle cells (SMCs), which results in depolarization of the latter and activation of voltage-gated L-type calcium channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1278179a52ae8b6a84874d1b0fd0f111
https://doi.org/10.1007/s11062-015-9464-7
https://doi.org/10.1007/s11062-015-9464-7
Autor:
Maksym I. Harhun, Khrystyna Yu. Sukhanova, V. A. Bouryi, Dmitri V. Gordienko, Oleksandr M. Thugorka
Publikováno v:
Pharmacological Reports. 66:363-372
ATP is one of the principal sympathetic neurotransmitters which contracts vascular smooth muscle cells (SMCs) via activation of ionotropic P2X receptors (P2XRs). We have recently demonstrated that contraction of the guinea pig small mesenteric arteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3130ed139bbb9848d6b4b97c32a35ad
https://doi.org/10.1016/j.pharep.2013.11.005
https://doi.org/10.1016/j.pharep.2013.11.005