Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dmitri Shcherbakov"'
Autor:
Heithem Boukari, Youjin Teo, Ivan Osinnii, James M. Moore, Eric Westhof, Stefan Duscha, Dmitri Shcherbakov, Adrian Cortes-Sanchon, Hubert Rehrauer, Margarita Brilkova, Reda Juskeviciene, Endre Laczko, Rashid Akbergenov, Matilde Mantovani, Harshitha Santhosh Kumar, Erik C. Böttger
Publikováno v:
Communications Biology
Communications Biology, Nature Publishing Group, 2019, 2 (1), ⟨10.1038/s42003-019-0626-9⟩
Communications Biology, Vol 2, Iss 1, Pp 1-16 (2019)
Communications Biology, 2
Communications Biology, Nature Publishing Group, 2019, 2 (1), ⟨10.1038/s42003-019-0626-9⟩
Communications Biology, Vol 2, Iss 1, Pp 1-16 (2019)
Communications Biology, 2
Translation fidelity is the limiting factor in the accuracy of gene expression. With an estimated frequency of 10−4, errors in mRNA decoding occur in a mostly stochastic manner. Little is known about the response of higher eukaryotes to chronic los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c871d4ecd0b902d4bc3c945aa65c2e4
https://hal.archives-ouvertes.fr/hal-02361126
https://hal.archives-ouvertes.fr/hal-02361126
Autor:
Sven N Hobbie, Marcel Kaiser, Sebastian Schmidt, Dmitri Shcherbakov, Tanja Janusic, Reto Brun, Erik C Böttger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1161 (2011)
Aminoglycoside antibiotics target the ribosomal decoding A-site and are active against a broad spectrum of bacteria. These compounds bind to a highly conserved stem-loop-stem structure in helix 44 of bacterial 16S rRNA. One particular aminoglycoside,
Externí odkaz:
https://doaj.org/article/a53037bf13a44faf86306d68ec2841ba
Autor:
Bruno Bernet, Dmitri Shcherbakov, Tanja Matt, Andrea Vasella, Stefan Duscha, Rashid Akbergenov, Eric Westhof, Martin Meyer, Shinde Harish, Sumanth R. Salian, Erik C. Böttger
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy; Vol 56
Antimicrobial Agents and Chemotherapy; Vol 56
The kanamycins form an important subgroup of the 4,6-disubstituted 2-deoxystreptamine aminoglycoside antibiotics, comprising kanamycin A, kanamycin B, tobramycin, and dibekacin. These compounds interfere with protein synthesis by targeting the riboso
Autor:
Erik C. Böttger, Srinivas Reddy Dubbaka, Su Hua Sha, Venki Ramakrishnan, Jochen Schacht, Martin Meyer, Chyan Leong Ng, Tanja Matt, Stefan Duscha, Rashid Akbergenov, Dmitri Shcherbakov, Jing Xie, Andrea Vasella, Kathrin Lang, Déborah Perez-Fernandez
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences; Vol 109
Proceedings of the National Academy of Sciences; Vol 109
Aminoglycosides are potent antibacterials, but therapy is compromised by substantial toxicity causing, in particular, irreversible hearing loss. Aminoglycoside ototoxicity occurs both in a sporadic dose-dependent and in a genetically predisposed fash
Autor:
Erik C. Böttger, Tanja Matt, Rashid Akbergenov, Martin Meyer, Dmitri Shcherbakov, Stefan Duscha, Daniel N. Wilson
Publikováno v:
Antimicrobial Agents and Chemotherapy
Capreomycin and the structurally similar compound viomycin are cyclic peptide antibiotics which are particularly active against Mycobacterium tuberculosis , including multidrug resistant strains. Both antibiotics bind across the ribosomal interface i
Autor:
Dmitri Shcherbakov, Peter Sander, Dan I. Andersson, Rashid Akbergenov, Erik C. Böttger, Tanja Matt
Publikováno v:
Molecular Microbiology. 77:830-840
Drug resistance in Mycobacterium tuberculosis is a global problem, with major consequences for treatment and public health systems. As the emergence and spread of drug-resistant tuberculosis epidemics is largely influenced by the impact of the resist
Autor:
Venki Ramakrishnan, Ng Chyan Leong, Déborah Perez-Fernandez, Erik C. Böttger, Rashid Akbergenov, Pia Thommes, Stefan Duscha, Pietro Freihofer, Kathrin Lang, Iwona Kudyba, Rashmi Patak, Heithem Boukari, Andrea Vasella, Dmitri Shcherbakov, Swapna Vaddi, Martin Meyer, Srinivas Reddy Dubbaka, Tanja Matt
Publikováno v:
Nature Communications
Nature Communications, 5
'Nature Communications ', vol: 5, pages: 3112-1-3112-11 (2014)
Nature Communications, 5
'Nature Communications ', vol: 5, pages: 3112-1-3112-11 (2014)
Clinical use of 2-deoxystreptamine aminoglycoside antibiotics, which target the bacterial ribosome, is compromised by adverse effects related to limited drug selectivity. Here we present a series of 4′,6′-O-acetal and 4′-O-ether modifications o
Autor:
Sebastian Schmidt, Sven N. Hobbie, Dmitri Shcherbakov, Erik C. Böttger, Reto Brun, Marcel Kaiser, Tanja Janusic
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1161 (2011)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Aminoglycoside antibiotics target the ribosomal decoding A-site and are active against a broad spectrum of bacteria. These compounds bind to a highly conserved stem-loop-stem structure in helix 44 of bacterial 16S rRNA. One particular aminoglycoside,
Publikováno v:
FEBS Letters. (1-3):123-128
The ribosomal protein S8 plays a pivotal role in the assembly of the 30S ribosomal subunit. Using filter binding assays, S8 proteins from mesophilic, and (hyper)thermophilic species of the archaeal genus Methanococcus and from the bacteria Escherichi
Autor:
Popov, Yuri A.1 popovpin@gmail.com
Publikováno v:
Boletín de la Sociedad Geológica Mexicana. 2016, Vol. 68 Issue 1, p23-27. 5p.