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of 4
pro vyhledávání: '"Dmitri Rozanov"'
Autor:
Dmitri Rozanov, Anton Cheltsov, Aaron Nilsen, Christopher Boniface, Isaac Forquer, James Korkola, Joe Gray, Jeffrey Tyner, Cristina E Tognon, Gordon B Mills, Paul Spellman
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0205623 (2019)
To determine the target of the recently identified lead compound NSC130362 that is responsible for its selective anti-cancer efficacy and safety in normal cells, structure-activity relationship (SAR) studies were conducted. First, NSC13062 was valida
Externí odkaz:
https://doaj.org/article/725ef1333a644e51a8aca39671124606
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122980 (2015)
Evidence suggests that stimulating apoptosis in malignant cells without inflicting collateral damage to the host's normal tissues is a promising cancer therapy. Chemo- and radiation therapies that, especially if combined, induce apoptosis in tumor ce
Externí odkaz:
https://doaj.org/article/7702c4866d17421b9003f6a87ed45717
Autor:
Dmitri Rozanov, Anton Cheltsov, Eduard Sergienko, Stefan Vasile, Vladislav Golubkov, Alexander E Aleshin, Trevor Levin, Elie Traer, Byron Hann, Julia Freimuth, Nikita Alexeev, Max A Alekseyev, Sergey P Budko, Hans Peter Bächinger, Paul Spellman
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129566 (2015)
A high throughput screen for compounds that induce TRAIL-mediated apoptosis identified ML100 as an active chemical probe, which potentiated TRAIL activity in prostate carcinoma PPC-1 and melanoma MDA-MB-435 cells. Follow-up in silico modeling and pro
Externí odkaz:
https://doaj.org/article/11106271d5e2407d9192a04d24ca2fe2
Autor:
Dmitri Rozanov, Ashok Reddy, Larry David, Gregory Burrows, Juha Rantala, Trevor Levin, Philip Wilmarth, Pavana Anur, Kami Chiotti, Paul Spellman
Publikováno v:
The Journal of Immunology. 190:214.2-214.2
In our search for better ways to stimulate anti-tumor T cell-mediated immune response we optimized powerful technique known as “reverse” immunogenetics, in which MHC I-bound peptides are recovered and sequenced using highly sensitive mass spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b9faccfb896e34a03067dd3b6737734
https://doi.org/10.4049/jimmunol.190.supp.214.2
https://doi.org/10.4049/jimmunol.190.supp.214.2