Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dmitri Negorev"'
Autor:
Tianyi Zhang, Matthew H. Levine, Evgeniy Eruslanov, Steven M. Albelda, Tatiana Akimova, Jason D. Christie, Sunil Singhal, Pratik Bhojnagarwala, Ulf H. Beier, Wayne W. Hancock, Falk W. Lohoff, Jon G. Quatromoni, Dmitri Negorev, Joshua M. Diamond
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
We report that human conventional CD15+ neutrophils can be isolated in the peripheral blood mononuclear cell (PBMC) layer during Ficoll gradient separation, and that they can impair T cell proliferation in vitro without concomitant neutrophil activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16676f3d7ec113bf8bba489c302ccb8
http://europepmc.org/articles/PMC5816646
http://europepmc.org/articles/PMC5816646
Autor:
Tatiana, Akimova, Tianyi, Zhang, Dmitri, Negorev, Sunil, Singhal, Jason, Stadanlick, Abhishek, Rao, Michael, Annunziata, Matthew H, Levine, Ulf H, Beier, Joshua M, Diamond, Jason D, Christie, Steven M, Albelda, Evgeniy B, Eruslanov, Wayne W, Hancock
Publikováno v:
JCI insight. 2(16)
Experimental data indicate that FOXP3+ Tregs can markedly curtail host antitumor immune responses, but the properties of human intratumoral Tregs are still largely unknown, in part due to significant methodologic problems. We studied the phenotypic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f16e3f97127c193feb7e58e48e6c69d
https://pubmed.ncbi.nlm.nih.gov/28814673
https://pubmed.ncbi.nlm.nih.gov/28814673
Autor:
Ilona U. Rafalska-Metcalf, Susan M. Janicki, Tian Yang, Gerd G. Maul, Dmitri Negorev, Alyshia Newhart
Publikováno v:
Molecular Biology of the Cell
Sp100 isoforms differentially regulate a CMV-promoter–regulated transcription site, which can be visualized in single cells. Sp100A promotes decondensation and increases lysine acetylation. However, it cannot overcome Daxx- and ATRX-mediated repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb3093530be3bd47314bf145f757483
http://europepmc.org/articles/PMC3639056
http://europepmc.org/articles/PMC3639056
Publikováno v:
Journal of Virology. 83:5168-5180
Cells have intrinsic defenses against virus infection, acting before the innate or the adaptive immune response. Preexisting antiviral proteins such as PML, Daxx, and Sp100 are stored in specific nuclear domains (ND10). In herpes simplex virus type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96763b6cac455a5762aeba36d398a5f
https://doi.org/10.1128/jvi.02083-08
https://doi.org/10.1128/jvi.02083-08
Autor:
Alexander M. Ishov, Jennifer S. Michaelson, Dmitri Negorev, Gerd G. Maul, Robert M. Tanguay, Isabelle Nefkens, Edward T.H. Yeh, Werner E.G. Müller
Publikováno v:
Journal of Cell Science. 116:513-524
Nuclear domains called ND10 or PML bodies might function as nuclear depots by recruiting or releasing certain proteins. Although recruitment of proteins through interferon-induced upregulation and SUMO-1 modification level of PML had been defined, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06905a970aac3d7a9f86a9ccac699f90
https://doi.org/10.1242/jcs.00253
https://doi.org/10.1242/jcs.00253
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 505:63-74
The protein encoded by the hepatitis B virus (HBV)-X gene, HBX, has been implicated to be involved in the development of HBV-associated liver cancer. HBX is a multifunctional regulatory protein that has been identified as a potential oncogene but its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee61a15a4902e56ab819e5f571d8222
https://doi.org/10.1016/s0027-5107(02)00140-9
https://doi.org/10.1016/s0027-5107(02)00140-9
Publikováno v:
Genes & Development. 16:919-932
Posttranslational modification of histones has emerged as a key regulatory signal in eukaryotic gene expression. Recent genetic and biochemical studies link H3-lysine 9 (H3-K9) methylation to HP1-mediated heterochromatin formation and gene silencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e6de94ca3cb7e1debf5538a45fc01a
https://doi.org/10.1101/gad.973302
https://doi.org/10.1101/gad.973302
Publikováno v:
Journal of Cell Science. 114:59-68
Nuclear domains called ND10 or PML nuclear bodies consist of an aggregation of several proteins, most notably PML and Sp100. PML is essential in the nucleation and formation of ND10 as well as in the recruitment of other ND10-associated proteins such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6150fba8b952c7fc9d0eece03e40be77
https://doi.org/10.1242/jcs.114.1.59
https://doi.org/10.1242/jcs.114.1.59
Publikováno v:
Journal of Structural Biology. 129:278-287
Nuclear domain 10 (ND10), also referred to as PML bodies or PODs, are discrete interchromosomal accumulations of several proteins including PML and Sp100. We describe here developments in the visualization of ND10 and the mechanism of ND10 assembly m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85797fdf16b633671043eb997636a41d
https://doi.org/10.1006/jsbi.2000.4239
https://doi.org/10.1006/jsbi.2000.4239
Publikováno v:
Cancer Genetics and Cytogenetics. 116:35-39
Recent data suggest that Bin1, a novel C-MYC interacting protein, is a suppressor gene whose loss of expression is a frequent aberration associated with several malignancies. The mechanism responsible for loss of BIN1 expression is not understood. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61df234ab1c2a274270fda0ea66b457
https://doi.org/10.1016/s0165-4608(99)00071-0
https://doi.org/10.1016/s0165-4608(99)00071-0