Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Dmitri, Volfson"'
Autor:
Jamie L. Adams, Tairmae Kangarloo, Yishu Gong, Vahe Khachadourian, Brian Tracey, Dmitri Volfson, Robert D. Latzman, Joshua Cosman, Jeremy Edgerton, David Anderson, Allen Best, Melissa A. Kostrzebski, Peggy Auinger, Peter Wilmot, Yvonne Pohlson, Stella Jensen-Roberts, Martijn L. T. M. Müller, Diane Stephenson, E. Ray Dorsey, the Parkinson Study Group Watch-PD Study Investigators and Collaborators
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Digital measures may provide objective, sensitive, real-world measures of disease progression in Parkinson’s disease (PD). However, multicenter longitudinal assessments of such measures are few. We recently demonstrated that baseline asses
Externí odkaz:
https://doaj.org/article/7b304f263c954a19b734d9277ee6190c
Autor:
Brian Tracey, Dmitri Volfson, James Glass, R’mani Haulcy, Melissa Kostrzebski, Jamie Adams, Tairmae Kangarloo, Amy Brodtmann, E. Ray Dorsey, Adam Vogel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract While speech biomarkers of disease have attracted increased interest in recent years, a challenge is that features derived from signal processing or machine learning approaches may lack clinical interpretability. As an example, Mel frequency
Externí odkaz:
https://doaj.org/article/e0ea7c4330da4036a2bfa9add0fd51ff
Autor:
Abirami Kugadas, Pietro Artoni, Wanida Ruangsiriluk, Meng Zhao, Natalia Boukharov, Rizwana Islam, Dmitri Volfson, Katayoun Derakhchan
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0304415 (2024)
Fabry disease (FD) is an X-linked disorder of glycosphingolipid metabolism caused by mutations in the GLA gene encoding alpha-galactosidase A (α-Gal). Loss of α-Gal activity leads to progressive lysosomal accumulation of α-Gal substrate, predomina
Externí odkaz:
https://doaj.org/article/a456c98473784a7382cca8158cfbd7d2
Autor:
Jamie L. Adams, Tairmae Kangarloo, Brian Tracey, Patricio O’Donnell, Dmitri Volfson, Robert D. Latzman, Neta Zach, Robert Alexander, Peter Bergethon, Joshua Cosman, David Anderson, Allen Best, Joan Severson, Melissa A. Kostrzebski, Peggy Auinger, Peter Wilmot, Yvonne Pohlson, Emma Waddell, Stella Jensen-Roberts, Yishu Gong, Krishna Praneeth Kilambi, Teresa Ruiz Herrero, E. Ray Dorsey, the Parkinson Study Group Watch-PD Study Investigators and Collaborators
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Digital health technologies can provide continuous monitoring and objective, real-world measures of Parkinson’s disease (PD), but have primarily been evaluated in small, single-site studies. In this 12-month, multicenter observational stud
Externí odkaz:
https://doaj.org/article/cc99401b7b5f4b508d697e05435b6623
Autor:
Rahul Ghosal, Vijay R. Varma, Dmitri Volfson, Jacek Urbanek, Jeffrey M. Hausdorff, Amber Watts, Vadim Zipunnikov
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Wearable data is a rich source of information that can provide a deeper understanding of links between human behaviors and human health. Existing modelling approaches use wearable data summarized at subject level via scalar summaries in regr
Externí odkaz:
https://doaj.org/article/926e79661363488c893cdce19765c3ce
Autor:
Nikhil Mahadevan, Charmaine Demanuele, Hao Zhang, Dmitri Volfson, Bryan Ho, Michael Kelley Erb, Shyamal Patel
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-12 (2020)
Abstract Objective assessment of Parkinson’s disease symptoms during daily life can help improve disease management and accelerate the development of new therapies. However, many current approaches require the use of multiple devices, or performanc
Externí odkaz:
https://doaj.org/article/870165e8401a411f8ef815626bfc3a7f
Autor:
Tara L. Moore, Damon A. Young, Ronald J. Killiany, Kari R. Fonseca, Dmitri Volfson, David L. Gray, Rita Balice-Gordon, Rouba Kozak
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Aged-related declines in cognition, especially working memory and executive function, begin in middle-age and these abilities are known to be mediated by the prefrontal cortex (PFC) and more specifically the dopamine (DA) system within the PFC. In bo
Externí odkaz:
https://doaj.org/article/de9abf602a974353b8531c96d2cb9afe
Autor:
Elena S. Izmailova, Ian L. McLean, Greg Hather, David Merberg, Jason Homsy, Matthew Cantor, Dmitri Volfson, Gaurav Bhatia, Eric D. Perakslis, Christopher Benko, John A. Wagner
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 6, Pp 677-686 (2019)
Wearable digital devices offer potential advantages over traditional methods for the collection of health‐related information, including continuous collection of dense data while study subjects are ambulatory or in remote settings. We assessed the
Externí odkaz:
https://doaj.org/article/90670d7afa5640249e7ccb5cebc8272f
Autor:
Vijay R. Varma, Rahul Ghosal, Inbar Hillel, Dmitri Volfson, Jordan Weiss, Jacek Urbanek, Jeffrey M. Hausdorff, Vadim Zipunnikov, Amber Watts
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Few studies have explored whether gait measured continuously within a community setting can identify individuals with Alzheimer's disease (AD). This study tests the feasibility of this method to identify individuals at the earli
Externí odkaz:
https://doaj.org/article/70239d0823ea4f3cbb161c6065b2393b
Autor:
Rouba Kozak, Tamás Kiss, Keith Dlugolenski, David E. Johnson, Roxanne R. Gorczyca, Kyle Kuszpit, Brian D. Harvey, Polina Stolyar, Stacey J. Sukoff Rizzo, William E. Hoffmann, Dmitri Volfson, Mihaly Hajós, Jennifer E. Davoren, Amanda L. Abbott, Graham V. Williams, Stacy A. Castner, David L. Gray
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Selective activation of dopamine D1 receptors remains a promising pro-cognitive therapeutic strategy awaiting robust clinical investigation. PF-6142 is a key example from a recently disclosed novel series of non-catechol agonists and partial agonists
Externí odkaz:
https://doaj.org/article/0f0c6a051bdf46babdb1a3b0bfe553ab