Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Dmitri, Sviridov"'
Autor:
Esperanza Muñoz-Muela, María Trujillo-Rodríguez, Ana Serna-Gallego, Abraham Saborido-Alconchel, Carmen Gasca-Capote, Ana Álvarez-Ríos, Ezequiel Ruiz-Mateos, Dmitri Sviridov, Andrew J. Murphy, Man K.S. Lee, Luis F. López-Cortés, Alicia Gutiérrez-Valencia
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105338- (2024)
Summary: Background: Among people living with HIV-1 (PHIV), immunological non-responders (INR) experience incomplete immune recovery despite suppressive antiretroviral treatment (ART), facing more severe non-AIDS events than immunological responders
Externí odkaz:
https://doaj.org/article/47ad10b8ca9a4c4b83f25cd317d658ff
Autor:
Christophe Vanpouille, Beda Brichacek, Tatiana Pushkarsky, Larisa Dubrovsky, Wendy Fitzgerald, Nigora Mukhamedova, Sofia Garcia‐Hernandez, Doreen Matthies, Anastas Popratiloff, Dmitri Sviridov, Leonid Margolis, Michael Bukrinsky
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) serve as pivotal mediators of intercellular communication in both health and disease, delivering biologically active molecules from vesicle‐producing cells to recipient cells. In the context of HIV infection, E
Externí odkaz:
https://doaj.org/article/33ef12fdef4d464c99b5528bf7286933
Autor:
Frank Stappenbeck, Feng Wang, Satyesh K. Sinha, Simon T. Hui, Lia Farahi, Nigora Mukhamedova, Andrew Fleetwood, Andrew J. Murphy, Dmitri Sviridov, Aldons J. Lusis, Farhad Parhami
Publikováno v:
Cells, Vol 13, Iss 19, p 1632 (2024)
Background and aims: We previously reported that Oxy210, an oxysterol-based drug candidate, exhibits antifibrotic and anti-inflammatory properties. We also showed that, in mice, it ameliorates hepatic hallmarks of non-alcoholic steatohepatitis (NASH)
Externí odkaz:
https://doaj.org/article/650e6a06b1ad4cdc92e89f9bd3345b48
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Findings that certain infections induce immunity not only against the causing agent, but also against an unrelated pathogen have intrigued investigators for many years. Recently, underlying mechanisms of this phenomenon have started to come to light.
Externí odkaz:
https://doaj.org/article/97e19d1636994478a30d8a39e0a321ea
Autor:
Alexei A. Adzhubei, Amol Kulkarni, Anna P. Tolstova, Anastasia A. Anashkina, Dmitri Sviridov, Alexander A. Makarov, Michael I. Bukrinsky
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3876-3884 (2021)
HIV-1 infection impairs cellular cholesterol efflux by downmodulating the cholesterol transporter ABCA1, leading to metabolic co-morbidities like cardio-vascular disease. The main mechanism of this effect is impairment by the HIV-1 protein Nef of the
Externí odkaz:
https://doaj.org/article/def5ff86429a43d9ae3f541d0c1c16c4
Autor:
Ryunosuke Ohkawa, Hann Low, Nigora Mukhamedova, Ying Fu, Shao-Jui Lai, Mai Sasaoka, Ayuko Hara, Azusa Yamazaki, Takahiro Kameda, Yuna Horiuchi, Peter J. Meikle, Gerard Pernes, Graeme Lancaster, Michael Ditiatkovski, Paul Nestel, Boris Vaisman, Denis Sviridov, Andrew Murphy, Alan T. Remaley, Dmitri Sviridov, Minoru Tozuka
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Externí odkaz:
https://doaj.org/article/c85e2bd927424090baf6850db15b6a1c
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 601-610 (2020)
Lipid rafts, solid regions of the plasma membrane enriched in cholesterol and glycosphingolipids, are essential parts of a cell. Functionally, lipid rafts present a platform that facilitates interaction of cells with the outside world. However, the u
Externí odkaz:
https://doaj.org/article/de55acac9bed4b19a6929c50372319a0
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 687-695 (2020)
Lipid rafts regulate the initiation of cellular metabolic and signaling pathways by organizing the pathway components in ordered microdomains on the cell surface. Cellular responses regulated by lipid rafts range from physiological to pathological, a
Externí odkaz:
https://doaj.org/article/4635d54e45ea4c14b8301877ddfe28ad
Autor:
Dmitri Sviridov, Yury I. Miller
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 598-600 (2020)
Lipid rafts are organized plasma membrane microdomains, which provide a distinct level of regulation of cellular metabolism and response to extracellular stimuli, affecting a diverse range of physiologic and pathologic processes. This Thematic Review
Externí odkaz:
https://doaj.org/article/262c21077b294858878ed7d0e4d94452
Autor:
Min Hi Park, Jeffrey L Suhalim, Firas Elmastour, Santu K Singha, Tadashi Imafuku, Ramanathan Venkatnarayan, Anette Christ, Alena Grebe, Sarah A Oppelt, Dmitri Sviridov, Michael Bukrinsky, Eicke Latz, Eric O Potma, Michael L Fitzgerald
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251599 (2021)
Chronic HIV infection may exacerbate atherosclerotic vascular disease, which at advanced stages presents as necrotic plaques rich in crystalline cholesterol. Such lesions can catastrophically rupture precipitating myocardial infarct and stroke, now i
Externí odkaz:
https://doaj.org/article/7d927e6dabde409bb967982a5d3e7a01