Lymphoid reconstitution after transplantation of congenic hematopoietic cells in busulfan-treated mice

Autor: AM Yeager, C Shinn, DM Pardoll

Publikováno v: Blood. 78(12)

The effects of pretransplant conditioning with high-dose busulfan, a myeloablative but nonimmunosuppressive alkylating agent, on reconstitution of lymphoid tissues by donor cells after bone marrow transplantation (BMT) has not been extensively examin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d229ff005d1a5e04e03d4cc9bc31f
https://pubmed.ncbi.nlm.nih.gov/1683798

Effects of cyclosporine A on T cell development and clonal deletion

Autor: MK Jenkins, RH Schwartz, DM Pardoll

Publikováno v: Science (New York, N.Y.). 241(4873)

Cyclosporine A (CsA) is an important immunosuppressive drug that is widely used in transplantation medicine. Many of its suppressive effects on T cells appear to be related to the inhibition of T cell receptor (TCR)-mediated activation events. Parado

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfbd461e58194eb24e4d5fec59e9f8d
https://pubmed.ncbi.nlm.nih.gov/3262237

Multidimensional Immunotyping of Human NF1-Associated Peripheral Nerve Sheath Tumors Uncovers Tumor-Associated Macrophages as Key Drivers of Immune Evasion in the Tumor Microenvironment.

Autor: Zhang L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Maalouf A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Makri SC; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Banerjee J; Sage Bionetworks, Seattle, Washington., Suru A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Tam AJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Calizo A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, Maryland., Pollard K; Laboratory Corporation of America (Labcorp), Burlington, North Carolina., Wang J; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Danilova L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Ioannou M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Levin AS; Department of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland., Morris CD; Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Rhee DS; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland., Belzberg AJ; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland., Blakeley JO; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ladle BH; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Pardoll DM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland., Lucas CG; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Rodriguez FJ; Department of Pathology, University of California Los Angeles, Los Angeles, California., Gross JM; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Anders RA; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Pratilas CA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland., Llosa NJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Dec 02; Vol. 30 (23), pp. 5459-5472.

The CCR6-CCL20 Axis Promotes Regulatory T-cell Glycolysis and Immunosuppression in Tumors.

Autor: Pant A; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Jain A; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Chen Y; Stanford Cancer Institute, Stanford School of Medicine, Stanford, California., Patel K; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Saleh L; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Tzeng S; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland., Nitta RT; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Zhao L; Department of Oncology and Medicine, Bloomberg-Kimmel Institute for Immunotherapy, the Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Wu CY; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Bederson M; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Wang WL; Stanford Cancer Institute, Stanford School of Medicine, Stanford, California., Bergsneider BH; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Choi J; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Medikonda R; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Verma R; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Cho KB; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Kim LH; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Kim JE; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Yazigi E; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Lee SY; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Rajendran S; Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, Ohio., Rajappa P; Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, Ohio., Mackall CL; Stanford Cancer Institute, Stanford School of Medicine, Stanford, California., Li G; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Tyler B; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Brem H; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Pardoll DM; Department of Oncology and Medicine, Bloomberg-Kimmel Institute for Immunotherapy, the Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland., Lim M; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, California., Jackson CM; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Nov 04; Vol. 12 (11), pp. 1542-1558.

Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response.

Autor: Han J; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Cherry C; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Mejías JC; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Krishnan K; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Ruta A; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Maestas DR Jr; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Peña AN; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Nguyen HH; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Nagaraj S; Department of Neurology, Brain Science Institute, Johns Hopkins University, Baltimore, MD, 21231, USA., Yang B; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Gray-Gaillard EF; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Rutkowski N; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Browne M; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA., Tam AJ; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Fertig EJ; Department of Biomedical Engineering and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21218, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.; Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, 21218, USA., Housseau F; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Ganguly S; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Moore EM; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA., Pardoll DM; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Elisseeff JH; Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA.; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Oct; Vol. 36 (43), pp. e2310476. Date of Electronic Publication: 2023 Dec 28.