Exploring the Role of Sialylated MUC1 (MUC1-ST) in Epithelial Injury and Fibrosis

Autor: Emma K Denneny, Joanna C. Porter, Joy Burchell, Richard Beatson, J. Sahota, Dlw Chong

Publikováno v: B64. MECHANISTIC ADVANCES IN LUNG FIBROSIS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb45b73b8aa04c4bd6e253b713724141
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4034

S79 Localised hypoxia enhances neutrophil extravasation and activation in interstitial lung disease

Autor: Ian Giles, Ashley M. Groves, Akif A. Khawaja, Helen Booth, Dlw Chong, J. Sahota, Margaret Ashcroft, Vera M. Ripoll, C Pericleous, LW Thomas, Joanna C. Porter, G Azzopardi

Publikováno v: Mechanistic insights into interstitial lung disease.

Background Neutrophilic inflammation is common in various diseases and may contribute to the pathophysiology of interstitial lung disease (ILD), however the underlying mechanism are not fully understood. Localised tissue hypoxia is often accompanied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32887dc6760776911fa13885f81299ee
https://doi.org/10.1136/thoraxjnl-2017-210983.85

S49 The role of platelet-derived TGFβ in pulmonary fibrosis

Autor: Joanna C. Porter, EJ Forty, Akif A. Khawaja, N Kanda, C Rebeyrol, Chris J. Scotton, Dlw Chong

Publikováno v: Thorax. 71:A30.1-A30

Background Pulmonary Fibrosis (PF) is characterised by abnormal wound healing involving fibroblast proliferation, myofibroblast differentiation and increased extracellular matrix deposition. TGFβ is an important driving force in fibrotic disease, ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d26a656a49220bf7a0981cdb66e2cf4
https://doi.org/10.1136/thoraxjnl-2016-209333.55

Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis.

Autor: Chong DLW; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.; Institute for Infection and Immunity, St George's University of London, London, United Kingdom., Mikolasch TA; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Sahota J; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Rebeyrol C; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Garthwaite HS; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Booth HL; Interstitial Lung Disease Service, University College London Hospital, London, United Kingdom., Heightman M; Interstitial Lung Disease Service, University College London Hospital, London, United Kingdom., Denneny EK; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., José RJ; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Khawaja AA; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Duckworth A; Department of Clinical and Biomedical Science, University of Exeter, Exeter, United Kingdom., Labelle M; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States., Scotton CJ; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.; Department of Clinical and Biomedical Science, University of Exeter, Exeter, United Kingdom., Porter JC; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Oct 01; Vol. 325 (4), pp. L487-L499. Date of Electronic Publication: 2023 Aug 29.

ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo .

Autor: Chong DLW; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom., Rebeyrol C; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom., José RJ; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom., Williams AE; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom., Brown JS; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom., Scotton CJ; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom.; Institute of Biomedical and Clinical Sciences, College of Medicine & Health, Exeter, United Kingdom., Porter JC; Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Aug 16; Vol. 12, pp. 691957. Date of Electronic Publication: 2021 Aug 16 (Print Publication: 2021).