Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Dlawer A A Ala'aldeen"'
Autor:
Eduardo Rojas, Johanna Hoyos, Neil J Oldfield, Philip Lee, Mike Flint, C Hal Jones, Dlawer A A Ala'Aldeen, Kathrin U Jansen, Annaliesa S Anderson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132140 (2015)
The reservoir for Neisseria meningitidis (Nm) is the human oropharynx. Implementation of Nm serogroup C (NmC) glycoconjugate vaccines directly reduced NmC carriage. Prophylactic vaccines are now available to prevent disease caused by the five major N
Externí odkaz:
https://doaj.org/article/36a9d7ded5454c5bac50ee98e296e884
Autor:
Neil J Oldfield, Suzan Matar, Fadil A Bidmos, Mohammed Alamro, Keith R Neal, David P J Turner, Christopher D Bayliss, Dlawer A A Ala'aldeen
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69746 (2013)
Neisseria meningitidis is a human nasopharyngeal commensal capable of causing life-threatening septicemia and meningitis. Many meningococcal surface structures, including the autotransporter proteins NalP and MspA, are subject to phase variation (PV)
Externí odkaz:
https://doaj.org/article/9843899e88734535bc4a8ea67087be38
Autor:
Noha M Abouseada, Mahde Saleh A Assafi, Jafar Mahdavi, Neil J Oldfield, Lee M Wheldon, Karl G Wooldridge, Dlawer A A Ala'Aldeen
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46233 (2012)
Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae Om
Externí odkaz:
https://doaj.org/article/fec9ce300b154828a3f36c6ebc13dda3
Autor:
Matthew Vassey, Rininta Firdaus, Akhmed Aslam, Lee M. Wheldon, Neil J. Oldfield, Dlawer A. A. Ala’Aldeen, Karl G. Wooldridge
Publikováno v:
Cellular Microbiology, Vol 2023 (2023)
Neisseria meningitidis is the most frequent cause of bacterial meningitis and is one of the few bacterial pathogens that can breach the blood-brain barrier (BBB). The 37/67 kDa laminin receptor (LamR) was previously identified as a receptor mediating
Externí odkaz:
https://doaj.org/article/80812655905a4ffbb15e7e36e8d17994
Autor:
Jafar Mahdavi, Necmettin Pirinccioglu, Neil J. Oldfield, Elisabet Carlsohn, Jeroen Stoof, Akhmed Aslam, Tim Self, Shaun A. Cawthraw, Liljana Petrovska, Natalie Colborne, Carina Sihlbom, Thomas Borén, Karl G. Wooldridge, Dlawer A. A. Ala'Aldeen
Publikováno v:
Open Biology, Vol 4, Iss 1 (2014)
Campylobacter jejuni is an important cause of human foodborne gastroenteritis; strategies to prevent infection are hampered by a poor understanding of the complex interactions between host and pathogen. Previous work showed that C. jejuni could bind
Externí odkaz:
https://doaj.org/article/a43fed16fc8d4a6ca44e25c81185865d
SummaryNeisseria meningitidisremains an important cause of human disease. It is highly adapted to the human host – its only known reservoir. Adaptations to the host environment include many specific interactions with human molecules including iron-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f409d9b38dc94facb0de009d31bdeef9
Autor:
Neil J. Oldfield, Jafar Mahdavi, Osman A. Dufailu, Karl G. Wooldridge, Dlawer A. A. Ala'Aldeen
Publikováno v:
Microbial pathogenesis. 124
Neisseria meningitidis is normally a human nasopharyngeal commensal but is also capable of causing life-threatening sepsis and meningitis. N. meningitidis secretes several virulence-associated proteins including Neisserial autotransporter lipoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b56a83ba81c21a90a54d42fb883434b
https://pubmed.ncbi.nlm.nih.gov/30081080
https://pubmed.ncbi.nlm.nih.gov/30081080
Autor:
Miriam Geörg, Neil J. Oldfield, Sherko A Omer, Karl G. Wooldridge, Hong Sjölinder, Ann-Beth Jonsson, Amir M. Ghaemmaghami, Osman A. Dufailu, Pierre-Joseph Royer, Ahmed S. Khairalla, Jafar Mahdavi, Tim Self, Dlawer A. A. Ala'Aldeen, Akhmed Aslam, Luisa Martinez-Pomares
Publikováno v:
Cellular Microbiology. 17:1008-1020
Neisseria meningitidis, a major cause of bacterial meningitis and septicaemia, secretes multiple virulence factors, including the adhesion and penetration protein (App) and meningococcal serine protease A (MspA). Both are conserved, immunogenic, type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae95dd3fe7fc1d5f78491d6bc2547d40
https://doi.org/10.1111/cmi.12417
https://doi.org/10.1111/cmi.12417
Autor:
Steven S. Smugar, Tessie McNeely, Nicholas A. Kartsonis, Dlawer A. A. Ala'Aldeen, Jean Marie Arduino, Barry N. Kreiswirth, Mark T. Esser, Annaliesa S. Anderson, Michael D. Raedler, Julie K. Zorman
Publikováno v:
Human Vaccines & Immunotherapeutics. 9:1857-1864
Staphylococcus aureus is a well-recognized, clinically important cause of nosocomial infections, and as such, a vaccine to prevent S. aureus infections would be an important achievement. A Phase IIB/III study of V710, a vaccine containing iron-regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85370f25112c08dfedd8da73ea53748
https://doi.org/10.4161/hv.25253
https://doi.org/10.4161/hv.25253
Autor:
Odile B. Harrison, Dlawer A. A. Ala'Aldeen, Martin C. J. Maiden, Neil J. Oldfield, Christopher D. Bayliss, David P. J. Turner
Background: Neisseria meningitidis is a frequent colonizer of the human nasopharynx, with asymptomatic carriage providing the reservoir for invasive, disease-causing strains. Serogroup Y (MenY) strains are a major cause of meningococcal disease. High
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e652425a557e99c267d86c082625750d
http://eprints.nottingham.ac.uk/31313/
http://eprints.nottingham.ac.uk/31313/