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Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.

Autor: Djojosubroto, Meta W., Chin, Allison C., Go, Ning, Schaetzlein, Sonja, Manns, Michael P., Gryaznov, Sergei, Harley, Calvin B., Rudolph, K. Lenhard

Publikováno v: Hepatology (02709139); Nov2005, Vol. 42 Issue 5, p1127-1136, 10p

Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

Autor: Choudhury AR; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Ju Z; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Djojosubroto MW; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Schienke A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Lechel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Schaetzlein S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Jiang H; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Stepczynska A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Department of Mucosal Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany., Wang C; Institute for Aging and Health, University of Newcastle Upon Tyne, Newcastle, UK., Buer J; Department of Mucosal Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Institute of Medical Microbiology, Hannover Medical School, Hannover, Germany., Lee HW; College of Science, Yonsei University, Seoul, Korea., von Zglinicki T; Institute for Aging and Health, University of Newcastle Upon Tyne, Newcastle, UK., Ganser A; Department of Hematology and Oncology, Hannover, Germany., Schirmacher P; Institute of Pathology, University Hospital, Heidelberg, Germany., Nakauchi H; Laboratory of Stem Cell Therapy, Institute of Medical Science, University of Tokyo, Tokyo, Japan., Rudolph KL; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany. Rudolph.Lenhard@MH-Hannover.de.

Publikováno v: Nature genetics [Nat Genet] 2020 May; Vol. 52 (5), pp. 548.