Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Djamila Ouaret"'
Autor:
Xin Li, Robert Berahovich, Hua Zhou, Xianghong Liu, Feng Li, Shirley Xu, Yuehua Wei, Djamila Ouaret, Walter Bodmer, Lijun Wu, Vita Golubovskaya
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 9, Pp 1765-1786 (2020)
Placental alkaline phosphatase, PLAP encoded by ALPP gene in humans is mainly expressed in placenta and testis, and not expressed in any other normal tissues. PLAP is overexpressed in colorectal cancers which makes it an attractive target for CAR (ch
Externí odkaz:
https://doaj.org/article/5bfdc71ff5d94eb9bc0e7c838cc4f713
Autor:
Rebecca Carter, Azadeh Cheraghchi-Bashi, Adam Westhorpe, Sheng Yu, Yasmin Shanneik, Elena Seraia, Djamila Ouaret, Yasuhiro Inoue, Catherine Koch, Jenny Wilding, Daniel Ebner, Anderson J. Ryan, Francesca M. Buffa, Ricky A. Sharma
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 2, Pp 234-246 (2019)
Objective Patients with BRAF-mutant colorectal cancer (CRC) have a poor prognosis. Molecular status is not currently used to select which drug to use in combination with radiotherapy. Our aim was to identify drugs that radiosensitise CRC cells with k
Externí odkaz:
https://doaj.org/article/20f6deba4d8f477f8d7767514aae6c9b
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 109-120 (2018)
Background: Colorectal cancer (CRC) liver metastasis is highly unfavorable for patient outcome and is a leading cause of cancer-related death. Pre-clinical research of CRC liver metastasis predominately utilizes CRC cell lines grown in tissue culture
Externí odkaz:
https://doaj.org/article/c5c6ee3165a140de940bb8bc4c445a43
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 2 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6143b96fa93dd17df198217419a851cb
https://doi.org/10.1158/1535-7163.22497007
https://doi.org/10.1158/1535-7163.22497007
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 1 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a19479773794b88b98afe698935106f
https://doi.org/10.1158/1535-7163.22497010
https://doi.org/10.1158/1535-7163.22497010
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 3 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568fdb909bd7c8e5b8b759927c62554f
https://doi.org/10.1158/1535-7163.22497004
https://doi.org/10.1158/1535-7163.22497004
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 4 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a2f8057a9be951437d8ffe613851a7
https://doi.org/10.1158/1535-7163.22497001
https://doi.org/10.1158/1535-7163.22497001
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
PM01183 is a novel marine-derived covalent DNA binder in clinical development. PM01183 is structurally similar to trabectedin (yondelis, ecteinascidin-743) except for the C subunit, and this modification is accompanied by different pharmacokinetics i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd29afa3bcc5f8ff9581b8efc6beead0
https://doi.org/10.1158/1535-7163.c.6535465
https://doi.org/10.1158/1535-7163.c.6535465
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Pharmacokinetic profiles of CEA TCB in mice, additional information on CD3 signaling, T cell activation, tumor cell lysis and cytokine release upon CEA TCB and untargeted control TCB treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d25ab83b90dec4d79470db61b3ea72f
https://doi.org/10.1158/1078-0432.22456472
https://doi.org/10.1158/1078-0432.22456472
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Purpose: CEA TCB is a novel IgG-based T-cell bispecific (TCB) antibody for the treatment of CEA-expressing solid tumors currently in phase I clinical trials (NCT02324257). Its format incorporates bivalent binding to CEA, a head-to-tail fusion of CEA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2428e20738f737283a333f7135109820
https://doi.org/10.1158/1078-0432.c.6523319.v1
https://doi.org/10.1158/1078-0432.c.6523319.v1