Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Dj, Kerr"'
Autor:
Kathryn McKay, Ifd Stephens, Jg Morrison, Robert S. Brown, Am Fichtingerschepman, Dj Kerr, Ma Graham, Donald Bissett
Publikováno v:
International journal of oncology. 2(1)
The adducts produced by the reaction of cis-diamminedichloroplatinum(II) with DNA have previously been isolated and characterised. These adducts may be measured at the cellular level by immunochemical detection but the accuracy of this assay is depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943712dd77fba4b308509cb421b707d8
https://pubmed.ncbi.nlm.nih.gov/21573512
https://pubmed.ncbi.nlm.nih.gov/21573512
Autor:
Dj, Dunlop, Eg, Wright, Lorimore S, Gj, Graham, tessa holyoake, Dj, Kerr, Sd, Wolpe, Ib, Pragnell
Publikováno v:
Europe PubMed Central
The proliferative status of the stem cell compartment is thought to be controlled by both positive and negative regulators of proliferation. These regulators have obvious clinical potential in manipulating the integrity and proliferative status of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfb0337647a2cdc158d85c5e5deb5b5
https://doi.org/10.1182/blood.v79.9.2221.bloodjournal7992221
https://doi.org/10.1182/blood.v79.9.2221.bloodjournal7992221
Publikováno v:
Europe PubMed Central
The virus-directed enzyme prodrug therapy (VDEPT) anti-cancer 'gene therapy' strategy relies on the use of viral vectors for the efficient delivery to tumour cells of a 'suicide gene' encoding an enzyme which converts a non-toxic prodrug to a cytotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cb5fab3a979c4c3241162d22f04fbdb9
https://pubmed.ncbi.nlm.nih.gov/10834268
https://pubmed.ncbi.nlm.nih.gov/10834268
Autor:
Pf, Searle, Sj, Weedon, Iain McNeish, Mg, Gilligan, Mj, Ford, Friedlos F, Cj, Springer, Ls, Young, Dj, Kerr
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7942339b17663961b99f1128e00f1bd2
https://pubmed.ncbi.nlm.nih.gov/10026858
https://pubmed.ncbi.nlm.nih.gov/10026858
Autor:
Nk, Green, Dj, Youngs, John Neoptolemos, Friedlos F, Rj, Knox, Cj, Springer, Gm, Anlezark, Np, Michael, Rg, Melton, Mj, Ford, Ls, Young, Dj, Kerr, Pf, Searle
Publikováno v:
Europe PubMed Central
Expression of genes encoding prodrug-activating enzymes can increase the susceptibility of tumor cells to prodrugs, and may ultimately achieve a better therapeutic index than conventional chemotherapy. CB1954 is a weak, monofunctional alkylating agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cc05eaf1c4392ea5f604f1e76548272a
https://pubmed.ncbi.nlm.nih.gov/9253508
https://pubmed.ncbi.nlm.nih.gov/9253508
Autor:
DJ Kerr
Publikováno v:
Cancer Research. 71:ES5-3
There is clear evidence that the global burden of cancer is increasingly affecting low and middle - income countries, effectively those nations who have least health infrastructure to deal with complex diseases like cancer. A new approach to cancer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45c31013d9c5db6b077a14ecdf4546ff
https://doi.org/10.1158/0008-5472.sabcs11-es5-3
https://doi.org/10.1158/0008-5472.sabcs11-es5-3
Publikováno v:
Europe PubMed Central
The recombinant plasmids p324, p330 and p323 carrying the aminoglycoside phosphotransferase (aph) gene and 5' flanking c-myc sequences linked to the reporter gene chloramphenicol acetyl-transferase (cat) were introduced into the mouse erythroleukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d9f5584d1dcb46902dcad9c2472fe985
https://pubmed.ncbi.nlm.nih.gov/1776855
https://pubmed.ncbi.nlm.nih.gov/1776855
Autor:
Mj, Mcgregor, Fadhil W, Wharton R, Yanagisawa Y, Presz M, Pritchard A, Womack C, Susan Dutton, Rs, Kerr, Dj, Kerr, Ec, Johnstone, Ilyas M
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::149ff63fae16e02052aa00f0cadd2289
http://www.scopus.com/inward/record.url?eid=2-s2.0-84924953091&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84924953091&partnerID=MN8TOARS
Autor:
Dj, Kerr, Sb, Kaye, John Graham, Cassidy J, Harding M, Setanoians A, Jc, Mcgrath, Wr, Vezin, Cunningham D, Forrest G
Publikováno v:
Europe PubMed Central
We have conducted a Phase I and initial clinical pharmacological evaluation of LM985, the first of a series of compounds based on the flavone ring structure to be considered for clinical trial in malignant disease. The drug was administered i.v. to 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6728b6164e9616d1f9939d41821997fb
http://europepmc.org/abstract/med/3698028
http://europepmc.org/abstract/med/3698028
Publikováno v:
Europe PubMed Central
Advanced ovarian cancer is characterized by poor prognosis and the development of resistance to chemotherapy. We have found that Bcl-2 and p53, two proteins implicated in the control of apoptosis, are differently expressed in the ovarian cell line A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d9ca608b810e2a80b861a103a1cf270e
http://europepmc.org/abstract/med/8616869
http://europepmc.org/abstract/med/8616869