Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Dj, Hicklin"'
Autor:
Liao F, Li Y, O'Connor W, Zanetta L, Bassi R, Santiago A, Overholser J, Hooper A, Mignatti P, ELISABETTA DEJANA, Dj, Hicklin, Bohlen P
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Vascular endothelial-cadherin (VE-cad) is an endothelial cell-specific adhesion molecule that is crucial for proper assembly of vascular tubes. Here we show that a monoclonal antibody (BV13) directed to the extracellular region of VE-cad inhibits for
Autor:
Hansen-Algenstaedt N, Br, Stoll, Timothy Padera, Dolmans DE, Dj, Hicklin, Fukumura D, Rk, Jain
Publikováno v:
Europe PubMed Central
Tumor oxygenation is critical for tumor survival as well as for response to therapy, e.g., radiation therapy. Hormone ablation therapy in certain hormone-dependent tumors and antiangiogenic therapy lead to vessel regression and have also shown benefi
Autor:
Liao F, Jf, Doody, Overholser J, Finnerty B, Bassi R, Wu Y, ELISABETTA DEJANA, Kussie P, Bohlen P, Dj, Hicklin
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::663e9297cd6508f2105599d3a542e410
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036570220&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036570220&partnerID=MN8TOARS
Autor:
Nirschl CJ; Werewolf Therapeutics, Watertown, Massachusetts., Brodkin HR; Werewolf Therapeutics, Watertown, Massachusetts., Domonkos C; Werewolf Therapeutics, Watertown, Massachusetts., Dwyer CJ; Werewolf Therapeutics, Watertown, Massachusetts., Hicklin DJ; Werewolf Therapeutics, Watertown, Massachusetts., Ismail N; Werewolf Therapeutics, Watertown, Massachusetts., Seidel-Dugan C; Werewolf Therapeutics, Watertown, Massachusetts., Steiner P; Werewolf Therapeutics, Watertown, Massachusetts., Steuert Z; Werewolf Therapeutics, Watertown, Massachusetts., Sullivan JM; Werewolf Therapeutics, Watertown, Massachusetts., Winston WM; Werewolf Therapeutics, Watertown, Massachusetts., Salmeron A; Werewolf Therapeutics, Watertown, Massachusetts.
Publikováno v:
Cancer immunology research [Cancer Immunol Res] 2023 Jul 05; Vol. 11 (7), pp. 962-977.
Autor:
Nirschl CJ, Brodkin HR, Hicklin DJ, Ismail N, Morris K, Seidel-Dugan C, Steiner P, Steuert Z, Sullivan JM, Tyagi E, Winston WM, Salmeron A
Publikováno v:
Cancer immunology research [Cancer Immunol Res] 2022 May 03; Vol. 10 (5), pp. 581-596.
Autor:
Shirasuna K; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan. Electronic address: kenna.shirasuna@astellas.com., Koelsch G; Drug Discovery Research, Astellas Pharma Inc., 1 Astellas Way, Northbrook, IL 60062, USA., Seidel-Dugan C; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Salmeron A; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Steiner P; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Winston WM; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Brodkin HR; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Nirschl CJ; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Abbott S; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Kinugasa F; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan., Sugahara S; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan., Ohori M; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan., Takeuchi M; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan., Hicklin DJ; Potenza Therapeutics, 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02138, USA., Yoshida T; Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.
Publikováno v:
Cancer treatment and research communications [Cancer Treat Res Commun] 2021; Vol. 28, pp. 100433. Date of Electronic Publication: 2021 Jul 11.
Autor:
Bogen SL; Discovery Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Pan W; Discovery Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Gibeau CR; Discovery Chemistry, Merck Research Laboratories , Boston, Massachusetts 02115, United States., Lahue BR; Discovery Chemistry, Merck Research Laboratories , Boston, Massachusetts 02115, United States., Ma Y; Discovery Chemistry, Merck Research Laboratories , Boston, Massachusetts 02115, United States., Nair LG; Discovery Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Seigel E; Discovery Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Shipps GW Jr; Discovery Chemistry, Merck Research Laboratories , Boston, Massachusetts 02115, United States., Tian Y; Discovery Chemistry, Merck Research Laboratories , Boston, Massachusetts 02115, United States., Wang Y; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Lin Y; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Liu M; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Liu S; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Mirza A; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Wang X; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Lipari P; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Seidel-Dugan C; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Hicklin DJ; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Bishop WR; Discovery Biology, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Rindgen D; Pharmacokinetic, Pharmacodynamics and Drug Metabolism, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Nomeir A; Pharmacokinetic, Pharmacodynamics and Drug Metabolism, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Prosise W; Structural Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Reichert P; Structural Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Scapin G; Structural Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Strickland C; Structural Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States., Doll RJ; Discovery Chemistry, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2016 Jan 20; Vol. 7 (3), pp. 324-9. Date of Electronic Publication: 2016 Jan 20 (Print Publication: 2016).
Autor:
Hicklin DJ; Potenza Therapeutics, Cambridge, Massachusetts. dhicklin@potenzatx.com.
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2015 Apr 01; Vol. 21 (7), pp. 1505-7.
Autor:
Jayson GC; Department of Medical Oncology, Christie Hospital and University of Manchester, Wilmslow Road, Manchester Academic Health Sciences Centre, Manchester M20 4BX, UK. gordon.jayson@manchester.ac.uk, Hicklin DJ, Ellis LM
Publikováno v:
Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2012 Feb 14; Vol. 9 (5), pp. 297-303. Date of Electronic Publication: 2012 Feb 14.
Autor:
Basso AD; Department of Oncology, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. andrea.basso@merck.com, Liu M, Gray K, Tevar S, Lee S, Liang L, Ponery A, Smith EB, Monsma FJ Jr, Yu T, Zhang Y, Kerekes AD, Esposite S, Xiao Y, Tagat JR, Hicklin DJ, Kirschmeier P
Publikováno v:
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2011 Oct; Vol. 68 (4), pp. 923-33. Date of Electronic Publication: 2011 Feb 05.