Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dj, Brull"'
Autor:
DJ Brull, Hugh Montgomery, James R. A. Skipworth, Michael G. Mythen, Steve E. Humphries, Julie Sanders, Jackie A. Cooper
Publikováno v:
International Journal of Cardiology. 157:180-184
Background A substantial proportion of patients suffer prolonged length of intensive care unit stay (PLOS) or prolonged mechanical ventilation (PMV) following coronary artery bypass grafting (CABG). Identifying factors associated with PLOS and PMV wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a6f09942688bc73fb305018fd0bde
https://doi.org/10.1016/j.ijcard.2010.12.011
https://doi.org/10.1016/j.ijcard.2010.12.011
Publikováno v:
Respiratory Medicine CME. 2:137-140
Summary Minocycline is a tetracycline antibiotic used for the treatment of acne. Minocycline has been associated with a variety of pulmonary adverse effects, most notably organising pneumonia and pulmonary infiltrates with eosinophilia. Most cases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4b3e2578871dd5f9823641e944012d
https://doi.org/10.1016/j.rmedc.2008.12.003
https://doi.org/10.1016/j.rmedc.2008.12.003
Autor:
Carmel Stock, Menachem Rubinstein, Steve E. Humphries, Daniela Novick, Simon Thompson, Jackie A. Cooper, George J. Miller, Julie Sanders, DJ Brull, Patricia Woo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:2743-2749
Objective— To investigate free interleukin-18 (fIL-18) levels, and variation within the IL-18 system genes, in heart surgery patients, and healthy men. Methods and Results— fIL-18 was calculated from IL-18 and IL-18 binding protein (BP) levels, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb06deb31402afc142a141889a19c59b
https://doi.org/10.1161/atvbaha.107.149245
https://doi.org/10.1161/atvbaha.107.149245
Autor:
Peter Taggart, Hugo D. Critchley, David G Groves, David Bradbury, Marcus A. Gray, Peter M. Sutton, DJ Brull, Diana R Holdright
Publikováno v:
Proceedings of the National Academy of Sciences. 104:6818-6823
Emotional trauma and psychological stress can precipitate cardiac arrhythmia and sudden death through arrhythmogenic effects of efferent sympathetic drive. Patients with preexisting heart disease are particularly at risk. Moreover, generation of proa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e641cd51b044775668a3cad462a94c
https://doi.org/10.1073/pnas.0609509104
https://doi.org/10.1073/pnas.0609509104
Publikováno v:
Pediatric Research. 58:117-120
The pro-inflammatory cytokine IL-6 may be neurocytopathogenic, and elevated levels are associated with impaired neurological outcome among children born prematurely. However, the precise mechanisms underlying this association remain unclear. The rare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c4bb4fa7d03f87383a4a9c4b4e9fb8
https://doi.org/10.1203/01.pdr.0000163523.49021.53
https://doi.org/10.1203/01.pdr.0000163523.49021.53
Autor:
Hugh Montgomery, DJ Brull
Publikováno v:
International Journal of Experimental Pathology. 81:283-287
Many of the symptoms of heart failure (breathlessness and fatigue) are not primarily due to reduced cardiac output, but relate to an impairment of peripheral muscle performance and metabolic efficiency. With regular training it is possible to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3629843f3e9a11f5e761c1045b9f932
https://doi.org/10.1111/j.1365-2613.2000.00167.x
https://doi.org/10.1111/j.1365-2613.2000.00167.x
Autor:
DJ Brull, Robin J. McAnulty, Richard P. Marshall, Geoffrey J. Laurent, Michael Hill, Steve E. Humphries, Anastasia Papafili
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 22:1631-1636
Objective— Cyclooxygenase (COX)-2 is a key regulatory enzyme in the synthesis of prostanoids associated with trauma and inflammation. We investigated the COX-2 gene for functional variants that may influence susceptibility to disease. Methods and R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c4f77308e4072db9f2edc83a583d3c
https://doi.org/10.1161/01.atv.0000030340.80207.c5
https://doi.org/10.1161/01.atv.0000030340.80207.c5
Autor:
Hugh Montgomery, M. DeDivitiis, C. P. M. Lesson, John E. Deanfield, Michael P. Mullen, DJ Brull, S.E. Humphries
Publikováno v:
European Journal of Clinical Investigation. 32:153-157
Aims Atherosclerosis is a chronic inflammatory condition, manifest in its early stages by endothelial dysfunction. Interleukin-6 (IL6) plays a key role in driving this process through stimulation of acute phase protein synthesis. We have examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a62847a89d54dc223fa38b9ec97f6b5c
https://doi.org/10.1046/j.1365-2362.2002.00966.x
https://doi.org/10.1046/j.1365-2362.2002.00966.x
Autor:
Hugh Montgomery, Ann Rumley, Sukhbir S. Dhamrait, Gordon D.O. Lowe, Julie Sanders, DJ Brull, Le-Anh Luong, S.E. Humphries
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 21:1458-1463
Interleukin-6 (IL-6) synthesized in response to diverse stimuli may play an important role in bridging the inflammatory and atherosclerotic processes. The acute-phase response after coronary artery bypass graft surgery (CABG) is associated with the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f204d138ea3e97293b94e7875db6377
https://doi.org/10.1161/hq0901.094280
https://doi.org/10.1161/hq0901.094280
Autor:
DJ Brull, Alison M. Gallagher, Steve E. Humphries, Liam J. Murray, Ian S. Young, Hugh Montgomery, Maurice Savage, Stuart H. Ralston, George Davey Smith, Colin Boreham, Fiona E. McGuigan
Publikováno v:
Hypertension. 38:444-448
—Reduced arterial compliance precedes changes in blood pressure, which may be mediated through alterations in vessel wall matrix composition. We investigated the effect of the collagen type I-α1 gene ( COL1A1 ) +2046G>T polymorphism on arterial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c99862d36eb90793346711d490e20c
https://doi.org/10.1161/01.hyp.38.3.444
https://doi.org/10.1161/01.hyp.38.3.444