Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Diya, Ren"'
Publikováno v:
International Journal of Computer Vision. 130:2733-2769
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc733e30338b0ef30e5a22fe460e6d3
https://doi.org/10.1007/s11263-022-01645-1
https://doi.org/10.1007/s11263-022-01645-1
Autor:
Kai Zheng, Diya Ren, Y. John Wang, Wayne Lilyestrom, Thomas Scherer, Justin K. Y. Hong, Junyan A. Ji
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3952 (2021)
Oxidation is an important degradation pathway of protein drugs. The susceptibility to oxidation is a common concern for therapeutic proteins as it may impact product efficacy and patient safety. In this work, we used 2,2′-azobis (2-amidinopropane)
Externí odkaz:
https://doaj.org/article/e4a9f9583ec54a609836950196e707ce
Publikováno v:
2022 the 5th International Conference on Image and Graphics Processing (ICIGP).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63feb7cd4b8ac902c5a8893e60757dcf
https://doi.org/10.1145/3512388.3512423
https://doi.org/10.1145/3512388.3512423
Autor:
Junyan A Ji, Y John Wang, Kai Zheng, Justin K Y Hong, Diya Ren, Wayne Lilyestrom, Thomas M. Scherer
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3952, p 3952 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3952, p 3952 (2021)
Oxidation is an important degradation pathway of protein drugs. The susceptibility to oxidation is a common concern for therapeutic proteins as it may impact product efficacy and patient safety. In this work, we used 2,2′-azobis (2-amidinopropane)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d2d69f2f72850333e44c5e3c419abd
https://pubmed.ncbi.nlm.nih.gov/33921206
https://pubmed.ncbi.nlm.nih.gov/33921206
Autor:
Diya Ren, Dengfeng Liu, Chris J. Wisniewski, Douglas S. Rehder, Matthew R. Schenauer, Dell Farnan
Publikováno v:
mAbs. 11:145-152
While characterizing a therapeutic IgG4 monoclonal antibody (mAb), we observed a variant with a mass 1177 Da larger than the predominant mAb form that could not be ascribed to previously described modifications. Through successive rounds of experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e0a9ad5efc8023ecf3d172f21056e
https://doi.org/10.1080/19420862.2018.1540254
https://doi.org/10.1080/19420862.2018.1540254
Publikováno v:
Journal of Chromatography B. 879:2877-2884
Sequence variants, also known as unintended amino acid substitutions in the protein primary structure, are one of the critical quality attributes needed to be monitored during process development of monoclonal antibodies (mAbs). Here we report on ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a2f8e09fdadecde6b567c7c5cdd9f9
https://doi.org/10.1016/j.jchromb.2011.08.015
https://doi.org/10.1016/j.jchromb.2011.08.015
Publikováno v:
Journal of Immunological Methods. 366:20-27
The detection of low level of protein A leached from monoclonal antibody downstream purification process is often interfered by the presence of excess amount of product antibody. In order to prevent this interference, we developed a new multi-product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7804726133672a0475e03c2156bf9d
https://doi.org/10.1016/j.jim.2011.02.003
https://doi.org/10.1016/j.jim.2011.02.003
Publikováno v:
Analytical Chemistry. 76:4522-4530
A new strategy for specifically targeting cysteine-containing peptides in a tryptic digest is described. The method is based on quantitatively derivatizing cysteine residues with a quaternary amine tag (QAT). Tags were introduced into proteins follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6218375be15f9b82709d5952325acb90
https://doi.org/10.1021/ac0354645
https://doi.org/10.1021/ac0354645
Publikováno v:
Journal of Proteome Research. 3:37-45
Agarose based immobilized copper (II) affinity chromatography (Cu(II)-IMAC) in tandem with reversed-phase chromatography was applied to a yeast protein extract. Histidine-rich peptides were selected and, in the process, samples were substantially sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2808ce52de0de9d95d0b381b4ef904
https://doi.org/10.1021/pr034049q
https://doi.org/10.1021/pr034049q
Publikováno v:
Journal of Proteome Research. 2:321-329
Agarose based immobilized metal affinity chromatography (IMAC) columns loaded with copper (II) were evaluated for the selection of histidine-containing peptides in comparative proteomics. Recovery, binding specificity, and reproducibility were invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fced5a8ce3ad55cb67c94cd0144330
https://doi.org/10.1021/pr034006+
https://doi.org/10.1021/pr034006+