Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dixie Ann Persaud-Sawin"'
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 4, Pp 759-767 (2009)
Membrane rafts are rich in cholesterol and sphingolipids and have specific proteins associated with them. Due to their small size, their identification and isolation have proved to be problematic. Their insolubility in nonionic detergents, such as Tr
Externí odkaz:
https://doaj.org/article/15172e0763104463b1ea78cd935020b2
Publikováno v:
Glia. 57:320-335
Microglial phagocytosis contributes to the maintenance of brain homeostasis. Mechanisms involved, however, remain unclear. Using Abeta(42) solely as a stimulant, we provide novel insight into regulation of microglial phagocytosis by rafts. We demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4e3b6abf0337d5ee649f13be4db247
https://doi.org/10.1002/glia.20759
https://doi.org/10.1002/glia.20759
Publikováno v:
Pediatric Research. 63:625-631
Juvenile neuronal ceroid lipofuscinosis (JNCL) belongs to the neuronal ceroid lipofuscinoses characterized by blindness/seizures/motor/cognitive decline and early death. JNCL is caused by CLN3 gene mutations that negatively modulate cell growth/apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4006c0c1e37dc23d5e05a8743a154595
https://doi.org/10.1203/pdr.0b013e31816fdc17
https://doi.org/10.1203/pdr.0b013e31816fdc17
Publikováno v:
Journal of Clinical Immunology. 26:406-416
Endothelial cell (EC) involvement in viral hemorrhagic fevers has been clearly established. However, virally activated mechanisms leading to endothelial activation and dysfunction are not well understood. Several different potential mechanisms such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0382f9a65be93bcc0cd5aec18814975a
https://doi.org/10.1007/s10875-006-9024-4
https://doi.org/10.1007/s10875-006-9024-4
Autor:
Adam Zucker, Ghassan Dbaibo, Alicja Bielawska, Talal Mousallem, Rose-Mary Boustany, Jacek Bielawski, Chiara Luberto, Maya Venkataramani, Joost C. M. Holthuis, Lina Kozhaya, Dixie-Ann Persaud-Sawin, S. Michal Jazwinski, Angela Schulz
Publikováno v:
Journal of Biological Chemistry. 281:2784-2794
A new variant of a group of pediatric neurodegenerative diseases known as neuronal ceroid lipofuscinosis (NCL) or Batten disease has been identified. It is termed CLN9-deficient. CLN9-deficient fibroblasts have a distinctive phenotype of rapid growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e108d691d27206e036a0283afe4f4463
https://doi.org/10.1074/jbc.m509483200
https://doi.org/10.1074/jbc.m509483200
Autor:
Eiki Kominami, Rose-Mary Boustany, Christine Wang, Adam Zucker, Talal Mousallem, Dixie-Ann Persaud-Sawin
Publikováno v:
Pediatric research. 61(2)
The neuronal ceroid lipofuscinoses are pediatric neurodegenerative diseases with common clinical features. Of the nine clinical variants (CLN1-CLN9), six have been genetically identified. Most variants manifest cell death and dysregulated sphingolipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8213d229d619533b9922292be20252c8
https://pubmed.ncbi.nlm.nih.gov/17237713
https://pubmed.ncbi.nlm.nih.gov/17237713
Autor:
Rose-Mary Boustany, Antonius M.J. VanDongen, Dixie-Ann Persaud-Sawin, James O. McNamara, Svetlana N. Rylova
Publikováno v:
Pediatric research. 56(3)
Juvenile neuronal ceroid lipofuscinosis (JNCL) is due to mutations in the CLN3 gene. We previously determined that CLN3 protein harbors a highly conserved motif, VYFAE, necessary for its impact on cell growth and apoptosis. Using molecular modeling w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b67881bda38baad871f57aa9cf16e7d
https://pubmed.ncbi.nlm.nih.gov/15240864
https://pubmed.ncbi.nlm.nih.gov/15240864
Autor:
M. G. Ribeiro, Janice A. Espinola, Carla Teixeira, A. Guimarães, Maria Clara Sá Miranda, Johannes Kohlschütter, Dixie Ann Persaud Sawin, Rose-Mary Boustany, Berge Minassian, Carlos J.P. Bessa, Marcy E. MacDonald, Dietrich A. Stephan, Liang Huo
Publikováno v:
Human mutation. 21(5)
The neuronal ceroid lipofuscinoses (NCLs) are a heterogeneous group of autosomal recessive neurodegenerative diseases comprising Batten and other related diseases plus numerous variants. They are characterized by progressive neuronal cell death. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59da59a74f593e0b824cbf883c116423
https://pubmed.ncbi.nlm.nih.gov/12673792
https://pubmed.ncbi.nlm.nih.gov/12673792
Autor:
Svetlana N, Rylova, Andrea, Amalfitano, Dixie-Ann, Persaud-Sawin, Wei-Xing, Guo, Jerry, Chang, Paul J, Jansen, Alan D, Proia, Rose-Mary, Boustany
Publikováno v:
Cancer research. 62(3)
Juvenile Batten disease is a neurodegenerative disease caused by accelerated apoptotic death of photoreceptors and neurons attributable to defects in the CLN3 gene. CLN3 is antiapoptotic when overexpressed in NT2 neuronal precursor cells. CLN3 negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e45e70497ff5c01eccef0c5f7b5cece
https://pubmed.ncbi.nlm.nih.gov/11830536
https://pubmed.ncbi.nlm.nih.gov/11830536
Autor:
Carla A. Teixeira, Janice Espinola, Liang Huo, Johannes Kohlschütter, Dixie-Ann Persaud Sawin, Berge Minassian, Carlos J. P. Bessa, A. Guimarães, Dietrich A. Stephan, Maria Clara Sá Miranda, Marcy E. MacDonald, Maria Gil Ribeiro, Rose-Mary N. Boustany
Publikováno v:
Human Mutation; May2003, Vol. 21 Issue 5, p502-508, 7p