Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Diwakar, Davar"'
Autor:
William H. Hicks, Lauren C. Gattie, Mohamad El Shami, Jeffrey I. Traylor, Diwakar Davar, Yana G. Najjar, Timothy E. Richardson, Samuel K. McBrayer, Kalil G. Abdullah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Despite advances in the treatment paradigm for patients with metastatic melanoma, melanoma brain metastasis (MBM) continues to represent a significant treatment challenge. The study of MBM is limited, in part, by shortcomings in existing pre
Externí odkaz:
https://doaj.org/article/cc6ec6088af94eb597fdd2740217f6ae
Autor:
Dmitriy Zamarin, Diwakar Davar, Adel Samson, Kevin J Harrington, Siddharth Sheth, Eric Tu, Mitesh J Borad, Grace K Dy, Evanthia Galanis, Fernanda Arnaldez, Sandip P Patel, Nicholas Durham, Benedito A Carneiro, Sonia Agrawal, Zhongying Chen, Chunling Fan, Maozhen Gong, Jenny Burton, Kevin Laubscher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background MEDI5395 is a recombinant attenuated Newcastle disease virus engineered to express a human granulocyte-macrophage colony-stimulating factor transgene. Preclinically, MEDI5395 demonstrated broad oncolytic activity, augmented by concomitant
Externí odkaz:
https://doaj.org/article/9b8ca43a8d514a34aab835d920738e15
Autor:
Amanda Enstrom, Diwakar Davar, Nehal Lakhani, Heidi LeBlanc, Stanford L Peng, Frank Schneider, Heather Thomas, Michael J Chisamore, Allison Naumovski, Ludimila Cavalcante, Sreenivasa Chandana, Joseph Schmalz, Krisztina Lengyel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Engagement of programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) can interfere with the CD28 signaling requisite for T-cell activation. While immune checkpoint inhibitors (ICIs) can relieve this suppression, they are u
Externí odkaz:
https://doaj.org/article/c9c952f6909f45a9bac6077e91d171b3
Autor:
Mark Voskoboynik, Justin Moser, Mario Sznol, Amita Patnaik, Amanda Enstrom, Diwakar Davar, Michael Millward, Rachel E Sanborn, Meredith McKean, Justin F Gainor, Nehal Lakhani, Heidi LeBlanc, Stanford L Peng, Heather Thomas, Lori Blanchfield, Michael J Chisamore, Allison Naumovski, Ludimila Cavalcante, Jaspreet S Grewal, Ajita Narayan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Davoceticept (ALPN-202) is an Fc fusion of a CD80 variant immunoglobulin domain designed to mediate programmed death-ligand 1 (PD-L1)-dependent CD28 co-stimulation while inhibiting the PD-L1 and cytotoxic T-lymphocyte-associated antigen 4
Externí odkaz:
https://doaj.org/article/09d04456db2341698a183766d4d11533
Autor:
Diwakar Davar, Yujia Liu, Jason Laporte, Prajna Guha, Steven C Katz, Chandra C Ghosh, Lauren Cournoyer, Alizee Ballarin, Ilan B Layman, Molly Morrissey, Kayla Fraser, Shriya Perati, Bryan F Cox, Evgeny Yakirevich, Diana O Treaba, Timothy D Murtha
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Toll-like receptor 9 (TLR9) agonists induce inflammatory responses that promote the killing of infectious micro-organisms, cancer cells and develop adaptive immune responses. Their ability as immunomodulators to enhance the activity of che
Externí odkaz:
https://doaj.org/article/a44effbe99ed410eaeba499fe1a1625d
Autor:
Bart Neyns, Mark Middleton, Aurélien Marabelle, Ignacio Melero, Ke Liu, Nina Bhardwaj, Tanja D de Gruijl, Jason Chesney, Robert Coffin, Howard Kaufman, Diwakar Davar, Jason J Luke, Georgina V Long, Kevin J Harrington, Sherene Loi, Thierry de Baere, David J Pinato, Matthew Fury, Ciara M Kelly, Joshua D Brody, Robert H Andtbacka, Gregory Goldmacher, Anuradha D Khilnani, Rahul A Sheth, Stephen B Solomon, Philippe Szapary
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Intratumorally delivered immunotherapies have the potential to favorably alter the local tumor microenvironment and may stimulate systemic host immunity, offering an alternative or adjunct to other local and systemic treatments. Despite th
Externí odkaz:
https://doaj.org/article/c46bb380ab4f4bb8bdb94dd95f2f7c6b
Publikováno v:
International Journal of Medical Students, Vol 11 (2023)
BACKGROUND: Vulvar malignant melanoma is a rare, often aggressive and recurring disease with a poorly understood prognosis. Here, we describe a patient with a longstanding vaginal cyst who was diagnosed with vulvar malignant melanoma upon a dermatolo
Externí odkaz:
https://doaj.org/article/6bcb4e1a719a4742b93310ed5ad3f66c
Autor:
Jishnu Das, Greg Delgoffe, Diwakar Davar, Stacy Wendell, Hector Nieves-Rosado, Bingxian Xie, Kristin Morder, Abigail E Overacre-Delgoffe, Drew Wilfahrt, Douglas Prado, Madison Nguyen, William Hawse, Larry Kane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/be8d9a0267ee49a1ac5247c566d6bffb
Autor:
Gregory A Daniels, Diwakar Davar, Theresa Medina, Michael R Migden, Trisha M Wise-Draper, Andrew S Poklepovic, Claire Verschraegen, Wanxing Chai-Ho, Jennifer C Tang, Praveen K Bommareddy, Shaheer A Khan, Katy K Tsai, Meenal Kheterpal, Diana Bolotin, Sherrif F Ibrahim, Nathalie C Zeitouni, Chris Tucci, Susan Navia, Laxminarasimha Donthireddy, Jeannie W Hou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2ea6485ff7a9466d90dc9a24c998398d
Autor:
Riyue Bao, Hassane Zarour, Yana G Najjar, Diwakar Davar, Cindy Sander, Jason J Luke, John M Kirkwood, Ryan C Augustin, Aofei Li, Marion Joy, Maureen Lyons, Katelyn Smith, Brian Isett, Sarah Brodeur, Mary Pham, Peter C Lucas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7e1d0dbe5b26476abc903e64734c0697