Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Divyoj Singh"'
Autor:
Aditi Ajith Pujar, Arnab Barua, Partha Sarathi Dey, Divyoj Singh, Ushasi Roy, Mohit Kumar Jolly, Haralampos Hatzikirou
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110569- (2024)
Summary: Notch-Delta-Jagged (NDJ) signaling among neighboring cells contributes crucially to spatiotemporal pattern formation and developmental decision-making. Despite numerous detailed mathematical models, their high-dimensionality parametric space
Externí odkaz:
https://doaj.org/article/d2350b3ceb6e483d85e1a358944fcf42
Autor:
Rashi Jindal, Abheepsa Nanda, Maalavika Pillai, Kathryn E. Ware, Divyoj Singh, Manas Sehgal, Andrew J. Armstrong, Jason A. Somarelli, Mohit Kumar Jolly
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1498-1509 (2023)
Advanced prostate cancer patients initially respond to hormone therapy, be it in the form of androgen deprivation therapy or second-generation hormone therapies, such as abiraterone acetate or enzalutamide. However, most men with prostate cancer even
Externí odkaz:
https://doaj.org/article/f5cf7b96175f41dbb8499a06f75362be
Publikováno v:
Entropy, Vol 23, Iss 3, p 288 (2021)
Non-genetic heterogeneity is emerging as a crucial factor underlying therapy resistance in multiple cancers. However, the design principles of regulatory networks underlying non-genetic heterogeneity in cancer remain poorly understood. Here, we inves
Externí odkaz:
https://doaj.org/article/a9f0f618920b4e1daa671771610305a0
Publikováno v:
ACS Omega. 8:3713-3725
Spatiotemporal pattern formation plays a key role in various biological phenomena including embryogenesis and neural network formation. Though the reaction-diffusion systems enabling pattern formation have been studied phenomenonlogically, the biomol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ca0f81fe6d9e23e016d95675f0bdf1
https://doi.org/10.1021/acsomega.2c04581
https://doi.org/10.1021/acsomega.2c04581
Planar Cell Polarity (PCP), characterized by asymmetric localization of proteins at the cell membrane within the epithelial plane, plays essential roles in embryonic development and physiological functions. The significance of PCP can be appreciated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34be6a3febbda066ffb5d75846f7e7af
https://doi.org/10.1101/2021.11.30.468758
https://doi.org/10.1101/2021.11.30.468758
Planar cell polarity (PCP) - asymmetric localization of proteins at cell-cell interface - is essential for embryonic development and physiological functions. Abnormalities in PCP can lead to neural tube closure defects, misalignment in hair follicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a022a25ddcd423b76a8f624c5a39153a
https://doi.org/10.1101/2021.11.30.468750
https://doi.org/10.1101/2021.11.30.468750
Autor:
Haralampos Hatzikirou, Aditi Ajith Pujar, Mohit Kumar Jolly, Ushasi Roy, Divyoj Singh, Arnab Barua
Phenotypic decision-making is a process of determining important phenotypes in accordance with the available microenvironmental information. Although phenotypic decision at the level of a single cell has been precisely studied, but the knowledge is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab63a46bed95f171703df08465ec7727
https://doi.org/10.1101/2021.11.16.468748
https://doi.org/10.1101/2021.11.16.468748
A stop codon ensures termination of translation at a specific position on an mRNA. Sometimes, termination fails as translation machinery recognizes a stop codon as a sense codon. This leads to stop codon readthrough (SCR) resulting in the continuatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::484b7b2b1fbf2be2b385b3f66c633910
https://doi.org/10.1101/2021.11.09.467898
https://doi.org/10.1101/2021.11.09.467898
Autor:
Sarthak Sahoo, Divyoj Singh, Anumeha Singh, Madhuparna Pandit, Kirtana Vasu, Saubhik Som, Naga Jyothi Pullagurla, Debabrata Laha, Sandeep M. Eswarappa
Publikováno v:
Journal of Biological Chemistry. 298:102173
Stop codon readthrough (SCR) is the process of continuation of translation beyond the stop codon, generating protein isoforms with C-terminal extensions. SCR has been observed in viruses, fungi, and multicellular organisms, including mammals. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e9dc5643383499a0e15b9ba2c54b89
https://doi.org/10.1016/j.jbc.2022.102173
https://doi.org/10.1016/j.jbc.2022.102173
Publikováno v:
Entropy
Volume 23
Issue 3
Entropy, Vol 23, Iss 288, p 288 (2021)
Volume 23
Issue 3
Entropy, Vol 23, Iss 288, p 288 (2021)
Non-genetic heterogeneity is emerging as a crucial factor underlying therapy resistance in multiple cancers. However, the design principles of regulatory networks underlying non-genetic heterogeneity in cancer remain poorly understood. Here, we inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40440f00f5c26148df6d8a7e4272fb