Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Divyen K. Shah"'
Autor:
Divyen K. Shah, Vennila Ponnusamy, Jane Evanson, Olga Kapellou, Georgia Ekitzidou, Neelam Gupta, Paul Clarke, Adina T. Michael-Titus, Ping K. Yip
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a604b1ec4ca5457aa2c4384a856dcb1d
Autor:
Simon C. Dyall, Isabell Nessel, Jennine A. Sharpe, Ping K. Yip, Adina T. Michael-Titus, Divyen K. Shah
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Hypoxic–ischemic encephalopathy (HIE) is a major cause of neonatal morbidity and mortality. Although therapeutic hypothermia is an effective treatment, substantial chronic neurological impairment often persists. The long-chain omega-3 polyunsaturat
Externí odkaz:
https://doaj.org/article/a36c9e28fe004dd38b288466668671cb
Autor:
Ping K. Yip, Michael Bremang, Ian Pike, Vennila Ponnusamy, Adina T. Michael-Titus, Divyen K. Shah
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1471 (2023)
Hypoxic-ischaemic encephalopathy (HIE) is an important cause of morbidity and mortality globally. Although mild therapeutic hypothermia (TH) may improve outcomes in selected babies, the mechanism of action is not fully understood. A proteomics discov
Externí odkaz:
https://doaj.org/article/5455a45f6e3141d7a65bdc0952f959dd
Autor:
Vennila Ponnusamy, Richard T. H. Ip, Moumin A. E. K. Mohamed, Paul Clarke, Eva Wozniak, Charles Mein, Leslie Schwendimann, Akif Barlas, Philippa Chisholm, Ela Chakkarapani, Adina T. Michael-Titus, Pierre Gressens, Ping K. Yip, Divyen K. Shah
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Using next generation sequencing of dried blood spots and subsequent validation, Ponnusamy et al identify let-7b-5p as an elevated microRNA in neonates with moderate to severe encephalopathy. Using cell culture and murine models of perinatal brain in
Externí odkaz:
https://doaj.org/article/1be6bfbde1764c6a85fd37f7b2291c5b
Autor:
Divyen K. Shah, Ping K. Yip, Akif Barlas, Pavithira Tharmapoopathy, Vennila Ponnusamy, Adina T. Michael-Titus, Philippa Chisholm
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Aim: To determine the predictive value of plasma neurofilament light protein (NfL) as a prognostic marker for outcomes in babies who have undergone therapeutic hypothermia (TH) for hypoxic ischemic encephalopathy (HIE).Method: NfL levels from three g
Externí odkaz:
https://doaj.org/article/fa118f3f1373492c86894a53dc1adcc8
Autor:
Divyen K. Shah, Vennila Ponnusamy, Jane Evanson, Olga Kapellou, Georgia Ekitzidou, Neelam Gupta, Paul Clarke, Adina T. Michael-Titus, Ping K. Yip
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Aims and hypothesisHypoxic-ischemic encephalopathy (HIE) remains an important cause of death and disability in newborns. Mild therapeutic hypothermia (TH) is safe and effective; however, there are no tissue biomarkers available at the bedside to sele
Externí odkaz:
https://doaj.org/article/2c6c8138cfb74e3f9e3029c78a2666c6
Autor:
Sujith S. Pereira, Stephen T. Kempley, David F. Wertheim, Ajay K. Sinha, Joan K. Morris, Divyen K. Shah
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
BackgroundCerebral electrical activity in extremely preterm infants is affected by various factors including blood gas and circulatory parameters.ObjectiveTo investigate whether continuously measured invasive mean arterial blood pressure (BP) is asso
Externí odkaz:
https://doaj.org/article/88fe7766647e43efa99e6a77cd0dd987
Publikováno v:
American Journal of Perinatology.
Objective This study aimed to examine the variation between clinician-recorded and continuously downloaded invasive blood pressure (BP). Study Design Prospective study where invasive BP data were downloaded every 10 seconds for the first week of life
Autor:
Charles A. Mein, Adina T. Michael-Titus, Ela Chakkarapani, Pierre Gressens, Moumin A. E. K. Mohamed, Eva Wozniak, Leslie Schwendimann, Divyen K Shah, Philippa Chisholm, Akif Barlas, Paul Clarke, Ping K. Yip, Richard T. H. Ip, Vennila Ponnusamy
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Despite increasing knowledge on microRNAs, their role in the pathogenesis of neonatal encephalopathy remains to be elucidated. Herein, we identify let-7b-5p as a significant microRNA in neonates with moderate to severe encephalopathy from dried blood
Autor:
Susana Pereira, Ryan Patel, Ahmed Zaima, Katarina Tvarozkova, Philippa Chisholm, Olga Kappelou, Jane Evanson, Edwin Chandraharan, David Wertheim, Divyen K. Shah
Commonly used methods of CTG classification do not reliably predict neonatal hypoxic-ischemic encephalopathy (HIE). To examine whether a relationship exists between the types of hypoxia as identified on the cardiotocograph using novel physiology-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e0df8f2d92fef69de9914a01363c9b