Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Divya Saro Varghese"'
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Background and aims The accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER) stress, which is a critical consequence in human disorders such as familial hypercholesterolemia,
Externí odkaz:
https://doaj.org/article/d9a5bfeb8a49475483a01fe270e1b6a0
Autor:
Sally Badawi, Divya Saro Varghese, Anjana Raj, Anne John, Hamda S. Al-Musafir, Ahmed J. Al-Ghamari, Alreem R. Alshamsi, Sara H. Ouda, Ghayth Al-Dirbashi, Bassam R. Ali
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Natriuretic peptide receptor 2 (NPR2 or NPR-B) plays a central role in growth development and bone morphogenesis and therefore loss-of-function variations in NPR2 gene have been reported to cause Acromesomelic Dysplasia, Maroteaux type
Externí odkaz:
https://doaj.org/article/1fc5103148154816b7ea686af1b2aa1f
Autor:
Divya Saro Varghese, Thilina T. Alawathugoda, Muhammad Abid Sheikh, Anil Kumar Challagandla, Bright Starling Emerald, Suraiya A. Ansari
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Obesity is a multigene disorder. However, in addition to genetic factors, environmental determinants also participate in developing obesity and related pathologies. Thus, obesity could be best described as a combination of genetic and enviro
Externí odkaz:
https://doaj.org/article/b89197db15e14adca77463ce3e684b57
Autor:
Divya Saro Varghese, Bassam R. Ali
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The oxidative modification of the major cholesterol carrying lipoprotein, oxLDL, is a biomarker as well as a pathological factor in cardiovascular diseases (CVD), type 2 diabetes mellitus (T2DM), obesity and other metabolic diseases. Perturbed cellul
Externí odkaz:
https://doaj.org/article/93c38d688a074c80a25c402a2957acff
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Familial hypercholesterolemia (FH) is an autosomal genetic disease characterized by high serum low-density lipoprotein (LDL) content leading to premature coronary artery disease. The main genetic and molecular causes of FH are mutations in low-densit
Externí odkaz:
https://doaj.org/article/ef9cebdfbde041f3a3fed71a0e615b44
Publikováno v:
Traffic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06331e24ed9c999fc154a018bbf7e6d5
https://doi.org/10.1111/tra.12902
https://doi.org/10.1111/tra.12902
Background and Aims- Endoplasmic Reticulum (ER) stress, caused by aberrantly trafficked proteins that are encoded by genetic variants of functional genes, is a critical consequence in human disorders such as familial hypercholesterolemia, cardiovascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d6f866f83668bf24e66ac1f70342d6
https://doi.org/10.21203/rs.3.rs-2615406/v1
https://doi.org/10.21203/rs.3.rs-2615406/v1
Publikováno v:
Journal of Reproductive Healthcare and Medicine. 4:3
Objectives: TAR DNA-binding protein of 43 kDa (TDP-43) is an RNA/DNA binding protein expressed in the brain and the testis. Mutations in TDP-43 lead to mislocalization and cytoplasmic aggregation of this protein causing neurodegenerative diseases suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92c79072b799fe496a3e33f2f7f4c78
https://doi.org/10.25259/jrhm_10_2022
https://doi.org/10.25259/jrhm_10_2022
Autor:
Ambili Soumya, Prabhakara P. Reddi, Divya Saro Varghese, Pradeep G. Kumar, Sathy M. Pillai, Krishnapillai Jayakrishnan, Uma Chandran
Publikováno v:
Reproduction, fertility, and development. 28(6)
Loss of function of TAR DNA-binding protein (TDP-43) has been implicated in neurodegenerative disorders in both humans and animal models. TDP-43 has also been shown to be cis-acting transcriptional repressor of the acrosome vesicle (Acrv) gene in mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fda02655ff0d14e04ac33612fec99df
https://pubmed.ncbi.nlm.nih.gov/25359468
https://pubmed.ncbi.nlm.nih.gov/25359468