Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Divya Duggal"'
Autor:
Divya Duggal, S. Requena, Janhavi Nagwekar, Sangram Raut, Ryan Rich, Hriday Das, Vipul Patel, Ignacy Gryczynski, Rafal Fudala, Zygmunt Gryczynski, Cheavar Blair, Kenneth S. Campbell, Julian Borejdo
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The systemic circulation offers larger resistance to the blood flow than the pulmonary system. Consequently, the left ventricle (LV) must pump blood with more force than the right ventricle (RV). The question arises whether the stronger pumping actio
Externí odkaz:
https://doaj.org/article/b17fdee6dfc149008598a180de7cc148
Autor:
Ryan Rich, Zygmunt Gryczynski, Rafal Fudala, Julian Borejdo, Sangram Raut, Janhavi Nagwekar, Ignacy Gryczynski, Divya Duggal
Publikováno v:
Medical Photonics. 27:1-8
We examined the effect of the differences in spatial arrangement of actin in contracting muscles from the left (LV) and right (RV) ventricles of rabbit heart. Spatial arrangement is a fundamental property of muscle because it reflects the interaction
Autor:
Rafal Fudala, Julian Borejdo, Janhavi Nagwekar, Zygmunt Gryczynski, Sangram Raut, Ryan Rich, Ignacy Gryczynski, Divya Duggal
Publikováno v:
Biochemistry
The contraction of the right ventricle (RV) expels blood into the pulmonary circulation, and the contraction of the left ventricle (LV) pumps blood into the systemic circulation through the aorta. The respective afterloads imposed on the LV and RV by
Autor:
Theodore P. Abraham, Gerrie P. Farman, Wenrui Huang, Danuta Szczesna-Cordary, Katarzyna Kazmierczak, Divya Duggal, Iraklis Pozios, Lars Sorensen, Jingsheng Liang, Julian Borejdo, Priya Muthu, Jeffrey R. Moore
Publikováno v:
Journal of Molecular and Cellular Cardiology. 74:318-329
article i nfo We have examined, for the first time, the effects of the familial hypertrophic cardiomyopathy (HCM)-associated Lys104Glu mutation in the myosin regulatory light chain (RLC). Transgenic mice expressing the Lys104Glu substitution (Tg-MUT)
Autor:
Julian Borejdo, Krishna Midde, Ignacy Gryczynski, Rafal Fudala, Janhavi Nagwekar, Divya Duggal, Ryan Rich
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 306:R222-R233
Force production in muscle results from ATP-driven cyclic interactions of myosin with actin. A myosin cross bridge consists of a globular head domain, containing actin and ATP-binding sites, and a neck domain with the associated light chain 1 (LC1) a
Autor:
Divya Duggal, Ignacy Gryczynski, Sunil Shah, Sangram Raut, Nirupama Sabnis, Joseph Kimball, Andras G. Lacko, Jaclyn Y. Bermudez, Rahul Chib, Zygmunt Gryczynski
Nanoparticles are target-specific drug delivery agents that are increasingly used in cancer therapy to enhance bioavailability and to reduce off target toxicity of anti-cancer agents. Valrubicin is an anti-cancer drug, currently approved only for ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80694248e60dbbef0e897e07162014d3
https://europepmc.org/articles/PMC5531042/
https://europepmc.org/articles/PMC5531042/
Autor:
Hriday K. Das, Danuta Szczesna-Cordary, Krishna Midde, Janhavi Nagwekar, Julian Borejdo, Rafal Fudala, Ryan Rich, Ignacy Gryczynski, Wenrui Huang, Divya Duggal
Familial hypertrophic cardiomyopathy (FHC) is the most common cause of sudden cardiac death in young individuals. Molecular mechanisms underlying this disorder are largely unknown; this study aims at revealing how disruptions in actin-myosin interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa20a50c9840c334dbb9cc1959bc88bf
https://europepmc.org/articles/PMC4436985/
https://europepmc.org/articles/PMC4436985/
Publikováno v:
Biophysical Journal. 110:126a-127a
The pressure necessary to expel blood into the pulmonary circulation by the right ventricle is smaller than the pressure necessary to pump blood into the systemic circulation by the left ventricle. Nevertheless, there is little reason to believe that
Autor:
Julian Borejdo, Janhavi Nagwekar, Ignacy Gryczynski, Divya Duggal, Hriday K. Das, Sangram Raut, Ryan Rich, Zygmunt Gryczynski
Publikováno v:
Biophysical Journal. 110:296a
Left ventricle (LV) and right ventricle (RV) differ in embryology, structure and function. Left ventricle originates from the primary heart field while right ventricle originates from the secondary heart field. The two heart fields express different
Autor:
Wenrui Huang, Krishna Midde, Janhavi Nagwekar, Danuta Szczesna-Cordary, Divya Duggal, Ryan Rich, Julian Borejdo, Rafal Fudala, Ignacy Gryczynski
Publikováno v:
Biophysical Journal. 106(2):563a-564a
Cross-bridge (XB) kinetics and the degree of order were examined in contracting myofibrils from the ex-vivo left ventricles of transgenic (Tg) mice expressing Familial Hypertrophic Cardiomyopathy (FHC) Regulatory Light Chain (RLC) mutation K104E. Sin