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Autor:
Digvijay Singh, Kelsey Gasior, Shan Lu, Olga Tapia, Amy S. Gladfelter, Elizabeth Villa, Don W. Cleveland, John R. Yates, Sandrine Da Cruz, Melinda S. Beccari, Divek Toprani, Jay M. Newby, Haiyang Yu, Miguel Lafarga, Sonia Vazquez-Sanchez
Publikováno v:
Science
The makings of anisosomes Phase separation of proteins within the cell can produce a liquid-inside-a-liquid phase resembling oil droplets in water. Yu et al. now report that an RNA-binding protein called TDP-43, in which mutation and aggregation are