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Nuclear phosphoinositides: their regulation and roles in nuclear functions

Autor: Fiume, R., Faenza, I., Sheth, B., Poli, A., Vidalle, M. C., Mazzetti, C., Abdul, S. H., Campagnoli, F., Fabbrini, M., Kimber, S. T., Mariani, G. A., Xian, J., Marvi, M. V., Mongiorgi, S., Shah, Z., Divecha, N.

Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in various sub-cellular co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______348::348bb4a9bf54d32fd3bff3a84a255fe3
https://eprints.soton.ac.uk/432836/

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output

Autor: Stijf-Bultsma, Y., Sommer, L., Tauber, M., Baalbaki, M., Giardoglou, P., Jones, D., Gelato, K., van Pelt, J., Shah, Z., Rahnamoun, H., Toma, C., Anderson, K., Hawkins, P., Lauberth, S., Haramis, A., Hart, D., Fischle, W., Divecha, N.

Publikováno v: Molecular Cell
Molecular Cell, 58(3), 453-467
Stijf-Bultsma, Y; Sommer, L; Tauber, M; Baalbaki, M; Giardoglou, P; Jones, DR; et al.(2015). The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output. Molecular Cell, 58(3), 453-467. doi: 10.1016/j.molcel.2015.03.009. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2qx5n3t8
Molecular cell, vol 58, iss 3

Summary Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how nuclear PI directly affects the transcriptional machinery is not known. We report that the lipid kinase PIP4K2B regula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ba43b3caefaa4127e2c89af5e677d84
http://europepmc.org/articles/PMC4429956

Nuclear phosphoinositides: location, regulation and function

Autor: FIUME, ROBERTA, FAENZA, IRENE, RAMAZZOTTI, GIULIA, MARTELLI, ALBERTO MARIA, FOLLO, MATILDE YUNG, COCCO, LUCIO ILDEBRANDO, Keune W. J., Bultsma Y., Jones D. R., Somner L., Divecha N.

Lipid signalling in human disease is an important field of investigation and stems from the fact that phosphoinositide signalling has been implicated in the control of nearly all the important cellular pathways including metabolism, cell cycle contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::b500ca206009801c2c8c3ce277a92367
http://hdl.handle.net/11585/119637

Evaluation and Optimization of ZIC-HILIC-RP as an alternative MudPIT Strategy

Autor: Boersema, P.J., Divecha, N, Heck, A.J.R., Mohammed, S., Biomoleculaire Massaspectrometrie, Biomolecular Mass Spectrometry and Proteomics, Comprehensive analysis of proteome analysis of B cell activation, Dep Farmaceutische wetenschappen, Dep Scheikunde

Publikováno v: Journal of Proteome Research, 6, 937. American Chemical Society

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::89b1ce4bd9c5798f69efdd355ba875ff
https://dspace.library.uu.nl/handle/1874/26377