Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Divas Neupane"'
Autor:
Maribel Beaumont, Daniela Tomazela, Douglas Hodges, Grigori Ermakov, Edward Hsieh, Isabel Figueroa, On-Yee So, Yaoli Song, Huiping Ma, Svetlana Antonenko, Wondwessen Mengesha, Yi Wei Zhang, Shuli Zhang, SuChun Hseih, Gulesi Ayanoglu, Xiaoyan Du, Eric Rimmer, Michael Judo, Franklin Vives, Jennifer H. Yearley, Christina Moon, Anthony Manibusan, Nick Knudsen, Andy Beck, Damien Bresson, Dennis Gately, Divas Neupane, Enrique Escandón
Publikováno v:
AAPS Open, Vol 4, Iss 1, Pp 1-17 (2018)
Abstract Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic
Externí odkaz:
https://doaj.org/article/d0889a1254a541b881e9c5aca5d58fd2
Autor:
Alexey V Danilov, Divas Neupane, Archana Sidalaghatta Nagaraja, Elena V Feofanova, Leigh Ann Humphries, James DiRenzo, Murray Korc
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192927 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0026815.].
Externí odkaz:
https://doaj.org/article/b009ba363c4d4fb8bced84b10d4d98e6
Autor:
Alexey V Danilov, Divas Neupane, Archana Sidalaghatta Nagaraja, Elena V Feofanova, Leigh Ann Humphries, James DiRenzo, Murray Korc
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26815 (2011)
Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to current chemotherapy regimens, in part due to alterations in the p53 tumor suppressor pathway. p53 homolog p63 is a transcription factor essential for the development and differentiation
Externí odkaz:
https://doaj.org/article/fd2ddc73e2ad45afae486a7f25e3bf63
Autor:
Derek Wiswell, Enrique Escandón, Alissa A. Chackerian, Shuli Zhang, Edward P. Bowman, Divas Neupane, Anandi Sawant, Douglas Linn, Minchao Chen
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 103:106872
Undesired immune responses against protein therapeutics may adversely affect the pharmacokinetics, efficacy, and safety of the product. The presence of anti-drug-antibodies (ADA) has been the key determinant of immunogenic responses. Here we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02ec358f5dd00e772e0cf159ec6381b
https://doi.org/10.1016/j.vascn.2020.106872
https://doi.org/10.1016/j.vascn.2020.106872
Autor:
SuChun Hseih, Daping Zhang, Daniel S. Spellman, Shuli Zhang, Yaoli Song, Harish Shankaran, Veronica Juan, Michael Judo, Sophia E Elie, Enrique Escandón, Vaishnavi Ganti, Divas Neupane, Wolfgang Seghezzi, Laurence Fayadat-Dilman, Mohammad Tabrizi
Publikováno v:
The AAPS journal. 21(3)
Assessment of the factors that regulate antibody exposure-response relationships in the relevant animal models is critical for the design of successful translational strategies from discovery to the clinic. Depending on the specific clinical indicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c85ebf94bfd8e0e0eba37382af7c29b
https://pubmed.ncbi.nlm.nih.gov/30868312
https://pubmed.ncbi.nlm.nih.gov/30868312
Autor:
Huiping Ma, SuChun Hseih, Shuli Zhang, Gulesi Ayanoglu, Christina Moon, Svetlana Antonenko, Damien Bresson, Isabel Figueroa, Eric Rimmer, Enrique Escandón, Edward Hsieh, Maribel Beaumont, Anthony Manibusan, Franklin Vives, Grigori Ermakov, Daniela M. Tomazela, Jennifer H. Yearley, Andrew H. Beck, Wondwessen Mengesha, Yaoli Song, On-Yee So, Divas Neupane, Michael Judo, Douglas Hodges, Yi Wei Zhang, Dennis Gately, Xiaoyan Du, Nick Knudsen
Publikováno v:
AAPS Open, Vol 4, Iss 1, Pp 1-17 (2018)
Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd018dbd2cdf16eeb7c9cfacdd32e689
https://doi.org/10.1186/s41120-018-0026-0
https://doi.org/10.1186/s41120-018-0026-0
Autor:
Divas Neupane, Murray Korc
Publikováno v:
Clinical Cancer Research. 14:7614-7623
Purpose: The purpose of the present study was to investigate the potential role of 14-3-3σ in pancreatic ductal adenocarcinoma (PDAC). Experimental Design: 14-3-3 isoform expression was determined by real-time quantitative PCR in laser capture norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06000d34047620004c70ff0615ae5290
https://doi.org/10.1158/1078-0432.ccr-08-1366
https://doi.org/10.1158/1078-0432.ccr-08-1366
Autor:
Divas Neupane, Leigh Ann Humphries, James DiRenzo, Alexey V. Danilov, Archana S. Nagaraja, Murray Korc, Elena V. Feofanova
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26815 (2011)
PLoS ONE
PLoS ONE
Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to current chemotherapy regimens, in part due to alterations in the p53 tumor suppressor pathway. p53 homolog p63 is a transcription factor essential for the development and differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20613d78fca2f9a4abe1535e642fa60
http://europepmc.org/articles/PMC3203907?pdf=render
http://europepmc.org/articles/PMC3203907?pdf=render
Autor:
Divas Neupane, John J. Krolewski, Abu Z M Saleh, Allison E. Arch, Ashraf El Fiky, Aaron T Fang
Publikováno v:
Oncogene. 23(42)
The type I interferons (IFNs) bind surface receptors, induce JAK kinases and activate STAT transcription factors to stimulate the transcription of genes downstream of IFN-stimulated response elements (ISREs). In this study, we demonstrate that IFNaR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf01bbcd4e643b1ab3c5f673e6e1496
https://pubmed.ncbi.nlm.nih.gov/15286706
https://pubmed.ncbi.nlm.nih.gov/15286706