Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Divakar S Mithal"'
Autor:
Varina L. Boerwinkle, Imani H. Sweatt, Aniela Grzezulkowska, William R. Reuther, Aaron Gelinne, Emilio G. Cediel, Divakar S. Mithal, Carolyn S. Quinsey, Scott W. Elton
Publikováno v:
Annals of the Child Neurology Society, Vol 2, Iss 3, Pp 225-234 (2024)
Abstract Objective The Child Neurology Society 2023 Annual Meeting Neurocritical Care Special Interest Group discussed pediatric opioid use–associated neurotoxicity with cerebellar edema (POUNCE). Inspired by the discussion and the suspicion of an
Externí odkaz:
https://doaj.org/article/1d25ee2de80f413c88becb407a636e49
Autor:
Divakar S Mithal, Jennifer P Rubin
Publikováno v:
Pediatric Neurology Briefs, Vol 32, Iss 0 (2018)
Investigators from Calico Life Sciences LLC and AbbVie report the effects of a novel drug targeting the genetic basis of Vanishing White Matter Disease (VWMD).
Externí odkaz:
https://doaj.org/article/cc9c47f0eeb840a6b857101586d2fba6
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128387 (2015)
Inflammatory (classical) monocytes residing in the bone marrow must enter the bloodstream in order to combat microbe infection. These monocytes express high levels of CCR2, a chemokine receptor whose activation is required for them to exit the bone m
Externí odkaz:
https://doaj.org/article/58d5dd0de74e4ba2b4f6c4b94ac0d900
Autor:
Parthiv Haldipur, Gwendolyn S Gillies, Olivia K Janson, Victor V Chizhikov, Divakar S Mithal, Richard J Miller, Kathleen J Millen
Publikováno v:
eLife, Vol 3 (2014)
Loss of Foxc1 is associated with Dandy-Walker malformation, the most common human cerebellar malformation characterized by cerebellar hypoplasia and an enlarged posterior fossa and fourth ventricle. Although expressed in the mouse posterior fossa mes
Externí odkaz:
https://doaj.org/article/6dc0ae03148e442297b9205442a87a09
Autor:
Hannah E. Munson, Lenika De Simone, Abigail Schwaede, Avanti Bhatia, Divakar S. Mithal, Nancy Young, Nancy Kuntz, Vamshi K. Rao
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Background Perrault Syndrome (PRLTS) is a rare, autosomal recessive disorder that presents with bilateral sensorineural hearing loss in all patients and gonadal dysfunction in females. It has been linked to variants in CLPP, ERAL1, HARS2, HS
Externí odkaz:
https://doaj.org/article/eceddc381f1b47cd82e184d306904d3c
Publikováno v:
Radiology Case Reports, Vol 16, Iss 4, Pp 807-810 (2021)
3-Hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency is a rare mitochondrial disorder of valine metabolism which may present with motor delay, hypotonia, ataxia, dystonia, seizures poor feeding, and organic aciduria. Neuroimaging findings include sig
Externí odkaz:
https://doaj.org/article/104b4b35162b402ead674a94050ac5e6
Autor:
Christopher J. Yuskaitis, Jinita B. Modasia, Sandra Schrötter, Leigh-Ana Rossitto, Karenna J. Groff, Christopher Morici, Divakar S. Mithal, Ram P. Chakrabarty, Navdeep S. Chandel, Brendan D. Manning, Mustafa Sahin
Publikováno v:
Cell reports. 40(9)
Caloric restriction and acute fasting are known to reduce seizures but through unclear mechanisms. mTOR signaling has been suggested as a potential mechanism for seizure protection from fasting. We demonstrate that brain mTORC1 signaling is reduced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501a8c0b940b959d2c6e81f4d20da12b
https://pubmed.ncbi.nlm.nih.gov/36044864
https://pubmed.ncbi.nlm.nih.gov/36044864
Autor:
Divakar S. Mithal, Navdeep S. Chandel
Publikováno v:
Cell metabolism. 33(10)
Leigh syndrome, a mitochondrial disease, can be modeled in mice with a deficiency in mitochondrial complex I that results in a decreased NAD+/NADH ratio. In this issue of Cell Metabolism, Liu et al. (2021) identify glycerol-3-phosphate (Gro3P) biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9266eb97d7ea9631db13e1fb43c9a4be
https://pubmed.ncbi.nlm.nih.gov/34270929
https://pubmed.ncbi.nlm.nih.gov/34270929
Autor:
Divakar S. Mithal, Navdeep S. Chandel
Publikováno v:
Molecular Cell. 80:381-383
Recent work by Licznerski et al. suggests that mutant FMRP linked to Fragile-X syndrome elevates the inner mitochondrial membrane proton leak, leading to increased metabolism and changes in protein synthesis that trigger impaired synaptic maturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::628b63c74b6b40de89de16602c423e45
https://doi.org/10.1016/j.molcel.2020.10.002
https://doi.org/10.1016/j.molcel.2020.10.002
Autor:
Divakar S, Mithal, Navdeep S, Chandel
Publikováno v:
Nature metabolism. 3(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71be5554f4ecad098b87a4f7d761e76d
https://pubmed.ncbi.nlm.nih.gov/33462513
https://pubmed.ncbi.nlm.nih.gov/33462513