Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ditte Z. Christensen"'
Autor:
Heidi Elbrønd-Bek, Casper René Gøtzsche, Ditte Z. Christensen, David P.D. Woldbye, Per Plenge, Mette Skinbjerg
Publikováno v:
International Journal of Peptide Research and Therapeutics. 21:269-278
The peptide transmitter neuropeptide Y (NPY) has been implicated in a plethora of actions in the central nervous system, including the hippocampus and neocortex (NeoCx). Previous studies using traditional receptor autoradiography show that NPY recept
Publikováno v:
Neurochemistry International. 63:54-60
Activity-regulated cytoskeletal-associated protein (Arc) and c-Fos are immediate early gene (IEG) products induced by novelty in the hippocampus and involved in the consolidation of synaptic plasticity and long-term memory. We investigated whether in
Autor:
Majbrit M. Jensen, Franziska Wichern, Marjorie C. Gondré-Lewis, Jens D. Mikkelsen, Ditte Z. Christensen, Morten S. Thomsen
Publikováno v:
Neuroscience. 346
The nicotinic acetylcholine receptor (nAChR) regulator chaperone (NACHO) was recently identified as an important regulator of nAChR maturation and surface expression. Here we show that NACHO levels decrease during early postnatal development in rats.
Publikováno v:
Neurobiology of Aging. 31:1153-1163
Loss of cholinergic neurons in the Nucleus Basalis of Meynert in Alzheimer's disease (AD) patients was one of the first discoveries of neuron loss in AD. Despite an intense focus on the cholinergic system in AD, the reason for this cholinergic neuron
Publikováno v:
Brain Research. 1301:116-125
The staining protocols so far applied to study intracellular Abeta accumulation in human tissue have been inconsistent with varying use of heat and formic acid (FA) for antigen retrieval. Microwave heat treatment has been reported to enhance the stai
Autor:
Morten S. Thomsen, John Paul Redrobe, Ditte Z. Christensen, Henrik H. Hansen, Jens D. Mikkelsen
Publikováno v:
Neuropharmacology. 56:1001-1009
The core features of schizophrenia include deficits in cognitive processes, such as attention and working memory, subserved by the prefrontal cortex (PFC). These deficits are believed to involve deficient neurotransmission through NMDA receptors, par
Autor:
Ditte Z, Christensen, Melanie, Huettenrauch, Miso, Mitkovski, Laurent, Pradier, Oliver, Wirths
Publikováno v:
Frontiers in Aging Neuroscience
Abnormalities and impairments in axonal transport are suggested to strongly contribute to the pathological alterations underlying AD. The exact mechanisms leading to axonopathy are currently unclear, but it was recently suggested that APP expression
Autor:
Mark J. West, Andreas Søderman, Jens D. Mikkelsen, Ditte Z. Christensen, Morten Skovgaard Jensen
Publikováno v:
Alzheimer's & Dementia. 6
Publikováno v:
Journal of Neurochemistry.
J. Neurochem. (2010) 114, 1205–1216. Abstract The α7 nicotinic acetylcholine receptor (nAChR) is an important target for treatment of cognitive deficits in schizophrenia and Alzheimer’s disease. However, the receptor desensitizes rapidly in vitr
Publikováno v:
Journal of neurochemistry. 114(4)
The alpha7 nicotinic acetylcholine receptor (nAChR) is an important target for treatment of cognitive deficits in schizophrenia and Alzheimer's disease. However, the receptor desensitizes rapidly in vitro, which has led to concern regarding its appli