Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ditte Olsen"'
Autor:
Carola Elisa Heesemann Rosenkilde, Ditte Olsen Lützhøft, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut bacteria are known to produce bacteriocins to inhibit the growth of other bacteria. Consequently, bacteriocins have attracted increased attention as potential microbiome-editing tools. In this study we examine the inhibitory spectrum of 75 class
Externí odkaz:
https://doaj.org/article/809e82b4d03144eb8780c0503cc9688d
Autor:
Ditte Olsen Lützhøft, Cecilie Bækgård, Elizabeth Wimborne, Ellen Marie Straarup, Karen-Margrethe Pedersen, Jonathan R Swann, Henrik Duelund Pedersen, Kim Kristensen, Line Morgills, Dennis Sandris Nielsen, Axel Kornerup Hansen, Marianne Kronborg Bracken, Susanna Cirera, Berit Østergaard Christoffersen
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298602 (2024)
The objectives were 1) to characterize a Göttingen Minipig model of metabolic syndrome regarding its colon microbiota and circulating microbial products, and 2) to assess whether ovariectomized female and castrated male minipigs show similar phenoty
Externí odkaz:
https://doaj.org/article/90a2b8f6cca8471cb76ca51ffe9a1c22
Autor:
Ditte Olsen Lützhøft, Tim Sinioja, Berit Ø. Christoffersen, Rasmus Riemer Jakobsen, Dawei Geng, Hajar Fauzan Bin Ahmad, Ellen Marie Straarup, Karen-Margrethe Pedersen, Witold Kot, Henrik Duelund Pedersen, Susanna Cirera, Tuulia Hyötyläinen, Dennis Sandris Nielsen, Axel Kornerup Hansen
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Gut microbiota dysbiosis is associated with the development of non-alcoholic steatohepatitis (NASH) through modulation of gut barrier, inflammation, lipid metabolism, bile acid signaling and short-chain fatty acid production. The
Externí odkaz:
https://doaj.org/article/a931ba6e887e454d981730582c3cb040
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://doaj.org/article/0dab2a5c70df4751af18ae27826dc208
Autor:
Ditte Olsen, Niels Wellner, Mathias Kaas, Inge E. M. de Jong, Florence Sotty, Michael Didriksen, Simon Glerup, Anders Nykjaer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Attention deficit hyperactivity disorder (ADHD) is the most frequently diagnosed neurodevelopmental disorder worldwide. Affected individuals present with hyperactivity, inattention, and cognitive deficits and display a characteristic paradox
Externí odkaz:
https://doaj.org/article/92593cd7cc714224b571f4954375bcbe
Autor:
Frederikke Christine Lindenberg, Ditte Olsen Lützhøft, Lukasz Krych, James Fielden, Witold Kot, Hanne Frøkiær, Gaby van Galen, Dennis Sandris Nielsen, Axel Kornerup Hansen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Some oligosaccharides induce growth of anti-inflammatory bacterial species and induce regulatory immunity in humans as well as animals. We have shown that the equine gut microbiota and the immune-microbial homeostasis largely stabilize within the fir
Externí odkaz:
https://doaj.org/article/8b3bdd7d30c54a528f95949f772d6598
Autor:
Camilla Gustafsen, Ditte Olsen, Joachim Vilstrup, Signe Lund, Anika Reinhardt, Niels Wellner, Torben Larsen, Christian B. F. Andersen, Kathrin Weyer, Jin-ping Li, Peter H. Seeberger, Søren Thirup, Peder Madsen, Simon Glerup
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
PCSK9 interacts with LDL receptor, causing its degradation, and consequently reduces the clearance of LDL. Here, Gustafsen et al. show that PCSK9 interacts with heparan sulfate proteoglycans and this binding favors LDLR degradation. Pharmacological i
Externí odkaz:
https://doaj.org/article/e6df4a8d335842ca8793c25354c164bc
Autor:
Ditte Olsen, Mathias Kaas, Jesper Lundhede, Simon Molgaard, Anders Nykjær, Mads Kjolby, Søren D. Østergaard, Simon Glerup
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Alcohol use disorder (AUD) is characterized by repetitive and uncontrolled intake of alcohol with severe consequences for affected individuals, their families and society as a whole. Numerous studies have implicated brain-derived neurotrophic factor
Externí odkaz:
https://doaj.org/article/2eb0704e7bb148ed81674a626ab636ad
Autor:
Simon Glerup, Maria Lume, Ditte Olsen, Jens R. Nyengaard, Christian B. Vaegter, Camilla Gustafsen, Erik I. Christensen, Mads Kjolby, Anders Hay-Schmidt, Dirk Bender, Peder Madsen, Mart Saarma, Anders Nykjaer, Claus M. Petersen
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 186-199 (2013)
Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or
Externí odkaz:
https://doaj.org/article/57be80328bf040d6b8ff9eb14d9de451
Autor:
Ditte Olsen, Camilla Gustafsen
Publikováno v:
Bio-Protocol, Vol 3, Iss 15 (2013)
This subcellular fractionation protocol is used for separation of cellular organelles based on their density. We have designed and optimized the protocol for separation of subcellular compartments of brain homogenates with focus on the localization a
Externí odkaz:
https://doaj.org/article/59b1a151204942a48ae182377bf7c820