Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Diterpenes/*pharmacology"'
Autor:
Guohua Zhao, Westley H. Reeves, Peter N. Kao, Daoming Qiu, Blaise Corthesy, Susan Lees-Miller, Lingfang Shi
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, vol. 35, no. 7, pp. 2302-10
Nucleic Acids Research, vol. 35, no. 7, pp. 2302-10
IL-2 gene expression in activated T-cells is initiated by chromatin remodeling at the IL-2 proximal promoter and conversion of a transcriptional repressor into a potent transcriptional activator. A purine-box regulator complex was purified from activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a7dd093cf5d80a764c69798b87a27
https://doi.org/10.1093/nar/gkm117
https://doi.org/10.1093/nar/gkm117
Autor:
Marios Marselos, Costas Demetzos, Basilios Vaos, Kostas Dimas, Mixalis Malamas, Theodoros Tzavaras, Dimitrios Kokkinopoulos
Publikováno v:
Leukemia Research. 23:217-234
Sclareol, a labdane-type diterpene, was tested for cytotoxic effect against a panel of established human leukemic cell lines. The compound showed an IC50 lower than 20 microg/ml in most cell lines tested, while it was higher for resting peripheral bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51134a6fab4deed299c7497cf7331774
https://doi.org/10.1016/s0145-2126(98)00134-9
https://doi.org/10.1016/s0145-2126(98)00134-9
Autor:
Steven R. Duncan, Glenn D. Rosen, Gerald J. Berry, James Theodore, Colm Leonard, Paola M. Soccal, Ramona L. Doyle
Publikováno v:
The Journal of heart and lung transplantation, Vol. 21, No 12 (2002) pp. 1314-8
The current treatment of obliterative bronchiolitis in lung transplant recipients is sub-optimal. Triptolide is a novel immunosuppressant that has a mechanism of action distinct from currently available immunosuppressants, including induction of T-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd983250fe621a646d2b2f77e340dbc
https://pubmed.ncbi.nlm.nih.gov/12490278
https://pubmed.ncbi.nlm.nih.gov/12490278
Publikováno v:
Leukemia research. 25(6)
Sclareol ( 1 ) and ent -3β-hydroxy-13-epi-manoyl oxide ( 2 ) belong to the labdane type diterpenes. They were isolated from the leaves and from the fruits of Cistus creticus subsp. creticus, and were found to be active against human leukemic cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04d5b4985de0676c2ba8eb659b21d21
https://pubmed.ncbi.nlm.nih.gov/11337016
https://pubmed.ncbi.nlm.nih.gov/11337016
Publikováno v:
Nucleic Acids Research. 12:1077-1086
Adenovirus types 2 and 5 DNA synthesized in vivo and in vitro in the presence of aphidicolin were studied. Inhibition of adenoviral DNA synthesis by aphidicolin was only 70% even at a concentration of 30 micrograms/ml of aphidicolin, at which the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a253bf115d916a0bf89fdaf7ad2a3757
https://doi.org/10.1093/nar/12.2.1077
https://doi.org/10.1093/nar/12.2.1077
Publikováno v:
Differentiation, 19 (1
The effects of aphidicolin - a powerful inhibitor of DNA polymerase alpha and of DNA replication - on normal development and on differentiation without cleavage of Chaetopterus eggs have been studied with cytological, cytochemical, and biochemical me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a19e14876dd0c61edaa917619167970
https://doi.org/10.1111/j.1432-0436.1981.tb01126.x
https://doi.org/10.1111/j.1432-0436.1981.tb01126.x
Autor:
Patrick Robberecht, Jean Christophe, Philippe De Neef, Jean Claude Camus, Jeanine Fontaine, Magali Waelbroeck
Publikováno v:
Pflügers Archiv, 401 (1
Secretin stimulated adenylate cyclase activity in crude membrane preparations from right and left rat atria, when tested in the presence of the potentiating activator forskolin. Its maximal effect on adenylate cyclase activity was greater in the righ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930f495bf90d2b67b70d1e2a56d50b12
https://pubmed.ncbi.nlm.nih.gov/6540864
https://pubmed.ncbi.nlm.nih.gov/6540864
Autor:
B. De Petrocellis, Jean Brachet
Publikováno v:
Experimental cell research, 135 (1
Aphidicolin, an inhibitor of DNA polymerase α, arrests DNA synthesis without affecting RNA and protein synthesis at all stages of sea urchin development. Cleavage is quickly stopped and hatching is prevented by the presence of the drug at 2 μg/ml.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65df781a8cbaa31489949a1685ced0e
https://pubmed.ncbi.nlm.nih.gov/6793376
https://pubmed.ncbi.nlm.nih.gov/6793376
Publikováno v:
Differentiation, 22 (2
Aphidicolin, a powerful inhibitor of nuclear DNA replication, has been used to establish the level of polyploidisation required for the realization of the late morphogenetic events (segregation, pseudogastrulation and ciliation) of differentiation wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2101::6df36b66b486d3f78bee13054595d978
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/172945
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/172945
Autor:
Alexandre, Henri
Publikováno v:
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie, 294 (21
Aphidicolin inhibits cleavage at every stage of preimplantation of Mouse embryos without affecting compaction. Blastulation is initiated only if the treatment is applied at the late 8-cell stage. It is concluded that the S phase of the 4th cell cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2101::4f153bb28de009348beff5cb435f80f6
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/221159
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/221159