Distributing human leukocyte antigen (HLA) database in histocompatibility: a shift in HLA data governance

Autor: Sirine Sayadi, Venceslas Douillard, Nicolas Vince, Mario Südholt, Pierre-Antoine Gourraud

Publikováno v: Exploration of Immunology, Vol 2, Iss 6, Pp 749-759 (2022)

Aim: Human leukocyte antigen (HLA) population genetics has been a historical field centralizing data resource. HLA genetics databases typically facilitate access to frequencies of allele, haplotype, and genotype format information. Among many resourc

Externí odkaz: https://doaj.org/article/609cf6ff75cb4a4ea70a021d627fe087

An Italian multicentre distributed data research network to study the use, effectiveness, and safety of immunosuppressive drugs in transplant patients: Framework and perspectives of the CESIT project

Autor: Valeria Belleudi, Alessandro C. Rosa, Marco Finocchietti, Francesca R. Poggi, Maria Lucia Marino, Marco Massari, Stefania Spila Alegiani, Lucia Masiero, Andrea Ricci, Gaia Bedeschi, Francesca Puoti, Massimo Cardillo, Silvia Pierobon, Maurizio Nordio, Eliana Ferroni, Martina Zanforlini, Giuseppe Piccolo, Olivia Leone, Stefano Ledda, Paolo Carta, Donatella Garau, Ersilia Lucenteforte, Marina Davoli, Antonio Addis, CESIT Study Group, Nera Agabiti, Michele Ercolanoni, Pamela Fiaschetti, Bedeschi Gaia, Valentina Ientile, Ursula Kirchmayer, Luca L’Abbate, Lorella Leoni, Olivia Lombardozzi, Claudia Lucia Marino, Maria Marino, Arianna Mazzone, Ugo Moretti, Andrea Angelo Nisic, Alessandra Oliveti, Daniela Peritore, Andrea Rosa, Alessandro C. Ricci, Vito Sparacino, Matilde Tanaglia, Silvia Trapani, Gianluca Trifirò, Manuel Zorzi

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

The goal of post-transplant immunosuppressive drug therapy is to prevent organ rejection while minimizing drug toxicities. In clinical practice, a multidrug approach is commonly used and involves drugs with different mechanisms of action, including c

Externí odkaz: https://doaj.org/article/ec1de07c8e2f45829a56fa78f79b76fb

Privacy-preserving harmonization via distributed ComBat

Autor: Andrew A. Chen, Chongliang Luo, Yong Chen, Russell T. Shinohara, Haochang Shou

Publikováno v: NeuroImage, Vol 248, Iss , Pp 118822- (2022)

Challenges in clinical data sharing and the need to protect data privacy have led to the development and popularization of methods that do not require directly transferring patient data. In neuroimaging, integration of data across multiple institutio

Externí odkaz: https://doaj.org/article/dd70822e81f44a1f9717417b33411b34

Watchdog – a workflow management system for the distributed analysis of large-scale experimental data

Autor: Michael Kluge, Caroline C. Friedel

Publikováno v: BMC Bioinformatics, Vol 19, Iss 1, Pp 1-13 (2018)

Abstract Background The development of high-throughput experimental technologies, such as next-generation sequencing, have led to new challenges for handling, analyzing and integrating the resulting large and diverse datasets. Bioinformatical analysi

Externí odkaz: https://doaj.org/article/92f07f7190d14ce2ade9b482a3a25c4a

Distributed Data Quality Assessment Across CORD-MI Consortia

Autor: Tahar, K, Martin, T, Mou, Y, Adnan, M, Geihs, S, Graessner, H, Krefting, D

Publikováno v: 67. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 13. Jahreskongress der Technologie-und Methodenplattform für die vernetzte medizinische Forschung e.V. (TMF); 20220821-20220825; sine loco [digital]; DOCAbstr. 103 /20220819/

Introduction: As a result of digitization, the importance of data quality (DQ) is increasing more and more, especially in the field of medicine and science [ref:1], [ref:2]. In the research project “Collaboration on Rare Diseases” of the Medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc03836023d05413994a83c0de5b845