αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation.

Autor: Uboveja A; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Huang Z; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Buj R; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Amalric A; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Wang H; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Tangudu NK; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Cole AR; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Megill E; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Kantner D; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Chatoff A; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Ahmad H; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Marcinkiewicz MM; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Disharoon JA; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Graff S; Department of Biochemistry, Albert Einstein College of Medicine, The Bronx, NY., Dahl ES; Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania., Hempel N; Department of Medicine, Division of Hematology/Oncology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, PA, USA., Stallaert W; Department of Computational & Systems Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Sidoli S; Department of Biochemistry, Albert Einstein College of Medicine, The Bronx, NY., Bitler BG; Division of Reproductive Sciences, University of Colorado Anschutz Medical Campus, Denver, Colorado., Long DT; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Snyder NW; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Aird KM; Department of Pharmacology & Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 11. Date of Electronic Publication: 2024 Feb 11.