Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Disha Thakkar"'
Autor:
Nishant Sharma, Monika Sharma, Disha Thakkar, Hemant Kumar, Sona Smetanova, Lucie Buresova, Petr Andrla, Amit Khairnar
BackgroundThe contribution of gastrointestinal (GI) inflammation and local exposure to neurotoxins in the gut offers the most in-depth explanation of Parkinson’s disease (PD) etiopathogenesis through abnormal accumulation and spreading of alpha-syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::638021d4f3adc1969ed6b84bb3e0f687
https://doi.org/10.1101/2022.12.22.521569
https://doi.org/10.1101/2022.12.22.521569
Autor:
Abhijeet S. Kate, Disha Thakkar
Publikováno v:
Drug Testing and Analysis. 12:331-342
Abemaciclib was approved by the US Food and Drug Administration in 2015 as an advanced treatment for metastatic breast cancer. Identification and characterization of limited numbers of abemaciclib metabolites have been reported in the literature. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81978cf5785ccae74d3d68e6a106b71b
https://doi.org/10.1002/dta.2725
https://doi.org/10.1002/dta.2725
Publikováno v:
Biomedical Chromatography. 35
Brexpiprazole (BRX) is approved for the treatment of schizophrenia and major depressive disorders and it is mainly metabolized by CYP3A4 and CYP2D6. Grapefruit juice (GFJ), pomegranate juice (PJ) and tomato juice (TJ) have the potential to inhibit CY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f529a7777d53e14fb8a8f04b8327136
https://doi.org/10.1002/bmc.5201
https://doi.org/10.1002/bmc.5201
Autor:
Disha Thakkar, Abhijeet S. Kate
Publikováno v:
Rapid Communications in Mass Spectrometry. 33:1024-1035
Rationale Brexpiprazole is a novel serotonin-dopamine activity modulator approved by the USFDA in July 2015 for the treatment of schizophrenia and as an adjunctive therapy with other antidepressants for major depressive disorder in adults. However, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05ed300e3498f68dd951ddbdbb6b370
https://doi.org/10.1002/rcm.8436
https://doi.org/10.1002/rcm.8436
Publikováno v:
Biomedical Chromatography. 35
IMID-2, a newly identified piperazine-based anticancer molecule, has been shown to be cytotoxic against various cancer cell lines. The primary aim of this research was to identify and characterize possible metabolites of the molecule formed during bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8464ad6261d6ad8b7a5bf6e2a9909d2e
https://doi.org/10.1002/bmc.5082
https://doi.org/10.1002/bmc.5082
Publikováno v:
Biomedical chromatography : BMCREFERENCES. 35(6)
IMID-2, a newly identified piperazine-based anticancer molecule, has been shown to be cytotoxic against various cancer cell lines. The primary aim of this research was to identify and characterize possible metabolites of the molecule formed during bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::482325e0069c227a9d926c791fd7a5ca
https://pubmed.ncbi.nlm.nih.gov/33570183
https://pubmed.ncbi.nlm.nih.gov/33570183
Autor:
David W. Chambers, Disha Thakkar
Publikováno v:
American Journal of Orthodontics and Dentofacial Orthopedics. 161:497-509.e4
The purpose of this systematic review and meta-analysis is to provide a literature-based estimate of the consistency of orthodontists' clinical decisions.A systematic review of the literature using a modified Reporting Items for Systematic Reviews an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e604237cda3ddcb2ea98140808211fa
https://doi.org/10.1016/j.ajodo.2021.05.009
https://doi.org/10.1016/j.ajodo.2021.05.009
Autor:
Abhijeet S. Kate, Disha Thakkar
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 45(3)
Brexpiprazole is an atypical antipsychotic approved for the treatment of schizophrenia and major depressive disorders in adults. The structure of brexpiprazole contains well-known structural alerts like a thiophene ring, piperazine ring and quinolino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b181dbd701a072f840ed813791a0f91
https://pubmed.ncbi.nlm.nih.gov/32002811
https://pubmed.ncbi.nlm.nih.gov/32002811
Publikováno v:
Critical reviews in analytical chemistry. 50(3)
Dysfunction of the antioxidant system or mutations in the gene may result in the elevated production of certain biomarkers. 3-nitrotyrosine (3-NT) is one such promising biomarker of oxidative stress formed due to nitration of protein bound and free t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9cd3a9657e8bf76ef5541220f0e677
https://pubmed.ncbi.nlm.nih.gov/31177807
https://pubmed.ncbi.nlm.nih.gov/31177807
Autor:
Monika Sharma, Amit Kumar Sahu, Amit Khairnar, Disha Thakkar, Maria Bandookwala, Pinaki Sengupta
Publikováno v:
Neuroscience letters. 711
Restoration of cellular microenvironment is important in the treatment of neurodegenerative diseases for optimal functioning and survival of neurons. Oxidative stress has been proposed as one of the major pathogenic drivers in Parkinson’s disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e69e3c7bf37d38e277d2f549ff0c001
https://pubmed.ncbi.nlm.nih.gov/31422100
https://pubmed.ncbi.nlm.nih.gov/31422100