Výsledky vyhledávání - "Diseases::Skin and Connective Tissue Diseases::Connective Tissue Diseases::Lupus Erythematosus, Systemic [Medical Subject Headings]"

The Role of BANK1 in B Cell Signaling and Disease

Autor: Gómez Hernández, Gonzalo, Morell, Maria, Alarcón-Riquelme, Marta E.

The B cell scaffold protein with ankyrin repeats (BANK1) is expressed primarily in B cells and with multiple but discrete roles in B cell signaling, including B cell receptor signaling, CD40-related signaling, and Toll-like receptor (TLR) signaling.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2636::323ebe28e3435cc16224e4b65d3c23ec
https://hdl.handle.net/10668/3880

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Therapeutic Potential and Immunomodulatory Role of Coenzyme Q10 and Its Analogues in Systemic Autoimmune Diseases

Autor: López-Pedrera, Chary, Villalba, José Manuel, Patiño-Trives, Alejandra Mª, Luque-Tévar, Maria, Barbarroja, Nuria, Aguirre, Mª Ángeles, Escudero-Contreras, Alejandro, Pérez-Sánchez, Carlos

Coenzyme Q10 (CoQ10) is a mitochondrial electron carrier and a powerful lipophilic antioxidant located in membranes and plasma lipoproteins. CoQ10 is endogenously synthesized and obtained from the diet, which has raised interest in its therapeutic po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2636::4dc49d858838d4f58dca0eb241835802
https://hdl.handle.net/10668/4208

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Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis

Autor: Christiana A. Demetriou, Zuzanna Makowska, George M. Spyrou, Marta E. Alarcón-Riquelme, Orthodoxia Nicolaou, Maria Morell, Bernard Lauwerys, Andreas Hadjisavvas, Savvas Psarellis, Andreas Kousios, Kyriacos Kyriacou, Pauline Montigny, Aurélie De Groof, Kleitos Sokratous, Anastasis Oulas, Kyriaki Michailidou

Publikováno v: Arthritis research & therapy, Vol. 22, no. 1, p. 147 [1-16] (2020)
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-16 (2020)
Arthritis Research & Therapy

Background Approximately 50% of systemic lupus erythematosus (SLE) patients develop nephritis, which is among the most severe and frequent complications of the disease and a leading cause of morbidity and mortality. Despite intensive research, there

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52526ad19de6c24a116ba20bdd056d85
https://doi.org/10.1186/s13075-020-02236-6

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Role of microRNAs in the Development of Cardiovascular Disease in Systemic Autoimmune Disorders

Autor: Lopez-Pedrera, Chary, Barbarroja, Nuria, Patiño-Trives, Alejandra Mª, Luque-Tévar, Maria, Torres-Granados, Carmen, Aguirre-Zamorano, Mª Angeles, Collantes-Estevez, Eduardo, Pérez-Sánchez, Carlos

Rheumatoid Arthritis (RA), Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are the systemic autoimmune diseases (SADs) most associated with an increased risk of developing cardiovascular (CV) events. Cardiovascular disease (CVD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2636::1390a4d618f5351501bf953b2337b1b8
https://hdl.handle.net/10668/3607

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First month prednisone dose predicts prednisone burden during the following 11 months: an observational study from the RELES cohort

Publikováno v: Lupus Science & Medicine
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Aim: To study the influence of prednisone dose during the first month after systemic lupus erythematosus (SLE) diagnosis (prednisone-1) on glucocorticoid burden during the subsequent 11 months (prednisone-2-12). Methods: 223 patients from the Registr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d236e67c5d8816f0be08fdcc444ebb
https://doi.org/10.1136/lupus-2016-000153

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Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene

Autor: María Francisca González-Escribano, Lina-Marcela Diaz-Gallo, Norberto Ortego-Centeno, Torsten Witte, Enrique de Ramón, Francisco J. García-Hernández, Hans-Joachim Anders, José Mario Sabio, Elena Sánchez, Miguel A. González-Gay, Javier Martín

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60646 (2013)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE

Creative Commons Attribution License.
The ubiquitin associated and Src-homology 3 (SH3) domain containing A (UBASH3a) is a suppressor of T-cell receptor signaling, underscoring antigen presentation to T-cells as a critical shared mechanism of di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23be62fd97726db6a461cefe33b2dcb9
https://hdl.handle.net/10668/1421

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Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus

Autor: José Luis Callejas, Francisco J. García-Hernández, José Mario Sabio, Juan Jiménez-Alonso, Rosa Garcia-Portales, Bobby P. C. Koeleman, Javier Martín, Enrique de Ramón, M F González-Escribano, Elena Sánchez

Publikováno v: BMC Medical Genetics, Vol 7, Iss 1, p 48 (2006)
Digital.CSIC. Repositorio Institucional del CSIC
instname
BMC Medical Genetics

This article is available from: http://www.biomedcentral.com/1471-2350/7/48
[Background] Several lines of evidence suggest that chemokines and cytokines play an important role in the inflammatory development and progression of systemic lupus ery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ffd09ebbe2e54e48284a96c976f681
http://www.biomedcentral.com/1471-2350/7/48

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