Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease [Medical Subject Headings]"'
Autor:
García-Casares, Natalia, Gallego Fuentes, Paloma, Barbancho, Miguel Ángel, López-Gigosos, Rosa, García-Rodríguez, Antonio, Gutiérrez-Bedmar, Mario
Alzheimer's Disease (AD) is a pathology with increasing prevalence in the context of a more long-lived society and it is the first cause of dementia in western countries. It is important to investigate factors that can be protective and may influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2636::aebb9411e701b0bd6ac612458f3d240e
https://hdl.handle.net/10668/4326
https://hdl.handle.net/10668/4326
Background The described relationship between Alzheimer’s disease (AD) and type 2 diabetes (T2D) and the fact that AD has no succesful treatment has led to the study of antidiabetic drugs that may limit or slow down AD pathology. Main body Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2636::e6eb9d8bf7ddf80fcfb9291f19ef0b74
https://hdl.handle.net/10668/4122
https://hdl.handle.net/10668/4122
Autor:
Juan Antonio Navarro, Cristina Rosell-Valle, Antonio J. López-Gambero, Carlos Sanjuan, Patricia Rivera, Antonio Vargas, Juan Suárez, Dina Medina-Vera, Fernando Rodríguez de Fonseca
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5365, p 5365 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5365, p 5365 (2021)
Increasing evidence links metabolic disorders with neurodegenerative processes including Alzheimer’s disease (AD). Late AD is associated with amyloid (Aβ) plaque accumulation, neuroinflammation, and central insulin resistance. Here, a humanized AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fbed2fd17fc0dd823107575e61dd77
https://hdl.handle.net/10668/4486
https://hdl.handle.net/10668/4486
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 18, Iss 2770, p 2770 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
International Journal of Environmental Research and Public Health
Volume 18
Issue 5
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
International Journal of Environmental Research and Public Health
Volume 18
Issue 5
Emotional processing, particularly facial expression recognition, is essential for social cognition, and dysfunction may be associated with poor cognitive health. In pathological ageing con-ditions, such as mild cognitive impairment (MCI) and Alzheim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf315393cb83aeeebf32ddc7dea4b78
https://www.mdpi.com/1660-4601/18/5/2770/pdf?version=1615294316
https://www.mdpi.com/1660-4601/18/5/2770/pdf?version=1615294316
Autor:
Rodrigo Morales, Nelson Perez-Urrutia, Ines Moreno-Gonzalez, Claudia Duran-Aniotz, Nazaret Gamez, Laura Vegas-Gomez, Claudio Soto
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Amyloid-β (Aβ) misfolding is one of the hallmark pathological features of Alzheimer’s disease (AD). AD can manifest with diverse symptomatology including variable rates of cognitive decline, duration of clinical disease, and other detrimental cha
Autor:
José Luis Trillo-Contreras, Pedro Gómez-Gálvez, Luis M. Escudero, Nieves Lara-Ureña, Andrea S. Bullones-Bolanos, Javier Vitorica, Miriam Echevarría, Rosana March-Díaz, Miguel Marchena, Jose Carlos Davila, Ana C. Sanchez-Hidalgo, Eloisa Herrera, Fernando de Castro, Jakob Körbelin, Antonia Gutierrez, Rocio González-Martínez, Alicia E. Rosales-Nieves, Raquel del Toro, Clara Ortega-de San Luis, Maria I. Alvarez-Vergara, Alberto Pascual, Pablo Vicente-Munuera, Manuel A. Sanchez-Garcia, Guiomar Rodriguez-Perinan, Martin Trepel, Francisco G. Scholl, Alberto Rábano, Javier Villadiego, Miguel Martin-Bornez, Beatriz Fernández-Gómez
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature is reduced around Aß plaques. Here we demonstrate that angiogenesis is started near Aß plaques in both AD mouse models and hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa049ed47a103e3d3ff4480d727c21b5
Autor:
Raquel Sanchez-Varo, Elisabeth Sanchez-Mejias, Juan Jose Fernandez-Valenzuela, Vanessa De Castro, Marina Mejias-Ortega, Angela Gomez-Arboledas, Sebastian Jimenez, Maria Virtudes Sanchez-Mico, Laura Trujillo-Estrada, Ines Moreno-Gonzalez, David Baglietto-Vargas, Marisa Vizuete, Jose Carlos Davila, Javier Vitorica, Antonia Gutierrez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
instname
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that progress to dementia. In this sense, synaptic dysfunction and loss have been established as the pathological features that best co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b35a0c3ca2eb2ebe0f860956a3c366c
http://hdl.handle.net/10261/269618
http://hdl.handle.net/10261/269618
Autor:
José Ríos, Amador Valladares, Irene Suárez-Pereira, Mónica Venegas-Calerón, José M. Monje-Moreno, Paula Sansigre, Sara Esteban-García, Marta Artal-Sanz, Manuel Muñoz, Javier Vitorica, Angel M. Carrión, Alicia Sánchez-García, Ana María Brokate-Llanos, Mercedes M. Pérez-Jiménez
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
12 Páginas.-- 5 Figuras
Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity. Here we show that loss of function of sul-2, the Caenorhabditis elegans steroid sulfatase
Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity. Here we show that loss of function of sul-2, the Caenorhabditis elegans steroid sulfatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e349166f272ab02aca1badb82eb4c
Autor:
Victoria Navarro, Javier Vitorica, Cristina Nuñez-Diaz, Sebastian Jimenez, Elisabeth Sanchez-Mejias, Angela Gomez-Arboledas, Clara Muñoz-Castro, Marisa Vizuete, Raquel Sanchez-Varo, Juan Jose Fernandez-Valenzuela, Ines Moreno-Gonzalez, Jose Carlos Davila, Antonia Gutierrez, Vanessa De Castro
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Scientific Reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Universidad de Sevilla (US)
Scientific Reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
In Alzheimer’s disease (AD), and other tauopathies, microtubule destabilization compromises axonal and synaptic integrity contributing to neurodegeneration. These diseases are characterized by the intracellular accumulation of hyperphosphorylated t
Autor:
López-Gambero, Antonio J., Sanjuan, Carlos, Serrano-Castro, Pedro Jesús, Suárez, Juan, Rodríguez de Fonseca, Fernando
Inositols are sugar-like compounds that are widely distributed in nature and are a part of membrane molecules, participating as second messengers in several cell-signaling processes. Isolation and characterization of inositol phosphoglycans containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2636::629cc5a6ecfc47d9b8e6804fd5d15724
https://hdl.handle.net/10668/3618
https://hdl.handle.net/10668/3618