Výsledky vyhledávání - "Disease-modifying therapie"

Ponesimod for the treatment of relapsing multiple sclerosis

Autor: Alessandra Lugaresi, Elisa Baldin

Publikováno v: Expert Opinion on Pharmacotherapy. 21:1955-1964

Introduction: Multiple Sclerosis (MS) is an immune-mediated, complex, chronic inflammatory, and neurodegenerative disease of the central nervous system. Among the several therapeutic options developed over the last decade for relapsing MS (RMS), fing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ba8fd525e001b6fde23c5278688281
https://doi.org/10.1080/14656566.2020.1799977

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Neurophysiological and behavioural correlates of ocrelizumab therapy on manual dexterity in patients with primary progressive multiple sclerosis

Autor: Raffaele Dubbioso, Marco Bove, Daniele Boccia, Vincenzo D’Ambrosio, Maria Nolano, Fiore Manganelli, Rosa Iodice

Background Hand dexterity impairment is a key feature of disability in people with primary progressive multiple sclerosis (PPMS). So far, ocrelizumab, a recombinant humanized monoclonal antibody that selectively depletes CD20-expressing B cells, is t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08413de70222d653b50a9675acd2f82b
http://hdl.handle.net/11588/883185

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Disease Reactivation in Secondary Progressive Multiple Sclerosis Patients Switching from Fingolimod to Siponimod: A Case Series

Autor: Gianmarco Abbadessa, Elisabetta Maida, Giuseppina Miele, Floriana Bile, Luigi Lavorgna, Simona Bonavita

Publikováno v: Journal of Clinical Medicine. 11:6033

Siponimod, a selective modulator of sphingosine 1-phosphate receptors 1 (S1P1) and 5 (S1P5), has recently been marketed for patients with Secondary Progressive Multiple Sclerosis (SPMS). Herein, we report three SPMS patients presenting disease reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5288fd59d9fecf83748e1d61a87e593
https://doi.org/10.3390/jcm11206033

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Adult-Onset Epilepsy in Presymptomatic Alzheimer’s Disease: A Retrospective Study

Autor: Ildebrando Appollonio, Giorgia Giussani, Jacopo C. DiFrancesco, Carlo Ferrarese, Valeria Polonia, Lucio Tremolizzo, Alessandro Nobili, Carlotta Franchi, Elisa Bianchi, Ettore Beghi

Publikováno v: Journal of Alzheimer's Disease. 60:1267-1274

Background The prevalence of epilepsy with onset in adulthood increases with age, mainly due to the accumulation of brain damage. However, a significant proportion of patients experience seizures of unknown cause. Alzheimer's disease (AD) is associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6736bae9a5f40b608c21d3f929e4e211
https://doi.org/10.3233/jad-170392

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Transthyretin amyloid cardiomyopathy: An uncharted territory awaiting discovery

Autor: Marco Merlo, Claudio Rapezzi, Gianfranco Sinagra, Aldostefano Porcari

Publikováno v: European Journal of Internal Medicine

Highlights • Transthyretin amyloid cardiomyopathy (ATTR-AC) is an under-diagnosed disease. • Many grey areas are emerging in clinical management and prognostic stratification. • Candidates’ selection for novel drugs is crucial, but response c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d626e622090d0ce7e1ab3c4db0a92a
https://www.sciencedirect.com/science/article/pii/S0953620520303770?via=ihub

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Risk of secondary progressive multiple sclerosis: A longitudinal study

Autor: Michael Barnett, Bhim Singhal, Maria Trojano, Franco Granella, Neil Shuey, Guillermo Izquierdo, Dana Horakova, Helmut Butzkueven, Talal Al-Harbi, Maria Laura Saladino, Cameron Shaw, Adam Fambiatos, Bart Van Wijmeersch, Serkan Ozakbas, Tünde Csépány, Freek Verheul, Cavit Boz, Tim Spelman, Pierre Duquette, Jeannette Lechner-Scott, Bassem Yamout, Roberto Bergamaschi, Vincent Van Pesch, Claudio Solaro, Edgardo Cristiano, Patrizia Sola, Vilija Jokubaitis, Jae Kwan Jun, Alessandra Lugaresi, Javier Olascoaga, Aysun Soysal, Thor Petersen, Mark Slee, Raed Alroughani, Francois Grand'Maison, Orla Gray, Tomas Kalincik, Marc Girard, Gerardo Iuliano, Anneke van der Walt, Eva Havrdova, Jose Luis Sanchez-Menoyo, Radek Ampapa, Julie Prevost, Steve Vucic, Pamela A. McCombe, Recai Turkoglu, Yara Dadalti Fragoso, Jordana Hughes, Olga Skibina, Murat Terzi, Eugenio Pucci, Diana Ferraro, Pierre Grammond, Fraser Moore, Ayse Altintas, Suzanne Hodgkinson, Youssef Sidhom, Norma Deri, Alexandre Prat, Raymond Hupperts, Daniele Spitaleri, Bruce V. Taylor

Publikováno v: Fambiatos, A, Jokubaitis, V, Horakova, D, Kubala Havrdova, E, Trojano, M, Prat, A, Girard, M, Duquette, P, Lugaresi, A, Izquierdo, G, Grand’Maison, F, Grammond, P, Sola, P, Ferraro, D, Alroughani, R, Terzi, M, Hupperts, R, Boz, C, Lechner-Scott, J, Pucci, E, Bergamaschi, R, Van Pesch, V, Ozakbas, S, Granella, F, Turkoglu, R, Iuliano, G, Spitaleri, D, McCombe, P, Solaro, C, Slee, M, Ampapa, R, Soysal, A, Petersen, T, Sanchez-Menoyo, J L, Verheul, F, Prevost, J, Sidhom, Y, Van Wijmeersch, B, Vucic, S, Cristiano, E, Saladino, M L, Deri, N, Barnett, M, Olascoaga, J, Moore, F, Skibina, O, Gray, O, Fragoso, Y, Yamout, B, Shaw, C, Singhal, B, Shuey, N, Hodgkinson, S, Altintas, A, Al-Harbi, T, Csepany, T, Taylor, B, Hughes, J, Jun, J K, van der Walt, A, Spelman, T, Butzkueven, H & Kalincik, T 2020, ' Risk of secondary progressive multiple sclerosis : A longitudinal study ', Multiple Sclerosis Journal, vol. 26, no. 1, pp. 79-90 . https://doi.org/10.1177/1352458519868990
Multiple sclerosis, Vol. 26, no. 1, p. 79-90 (2020)

Turkoglu, Recai/0000-0001-9724-851X; Ferraro, Diana/0000-0003-4818-3806; McCombe, Pamela/0000-0003-2704-8517; Altintas, Ayse/0000-0002-8524-5087; Jokubaitis, Vilija G./0000-0002-3942-4340; Slee, Mark/0000-0003-4323-2453; Lugaresi, Alessandra/0000-000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cd799ef882d65d54c9d7ef34b33e78
https://avesis.deu.edu.tr/publication/details/fb9b47c1-d816-40b5-86de-96e112b6f8f9/oai

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