Zobrazeno 1 - 10
of 949
pro vyhledávání: '"Disease modifying treatment"'
Autor:
A. N. Boyko, V. M. Alifirova, D. V. Pashkovskaya, E. I. Kuchina, S. A. Sivertseva, E. L. Turova, Z. A. Goncharova, O. Yu. Rudenko, Yu. Yu. Pogrebnova, F. A. Khabirov, T. I. Khaibullin, N. N. Babicheva, N. L. Khoroshilova, O. V. Dzundza, O. A. Soldatova, A. N. Belova, G. Е. Sheiko, A. Е. Makarova, N. G. Glavinskaya
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 0, Pp 44-50 (2024)
Multiple sclerosis (MS) is an autoimmune-inflammatory and neurodegenerative disease of the central nervous system. The article analyses the ability of cladribine, which due to its selective lymphotoxic effect on activated cells and central effect on
Externí odkaz:
https://doaj.org/article/13341d6d8452436192ed66135a401fd3
Publikováno v:
Journal of IMAB, Vol 30, Iss 2, Pp 5527-5532 (2024)
Background: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by demyelination, axonal damage and loss of neurons. Its growing incidence has determined the need for more inte
Externí odkaz:
https://doaj.org/article/266986087b5c45d0895c5963d2c53110
Autor:
Eman M. Khedr, Doaa M. Mahmoud, Hussein B. Hussein, Islam E. L. Malky, Sarah S. Mostafa, Ayman Gamea
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Despite the proven efficacy of the disease-modifying therapy (DMT) for multiple sclerosis (MS), the rates of non-adherence are frequently high. We aimed to evaluate the rate of non-adherence to the first DMT in Upper Egypt and identify diffe
Externí odkaz:
https://doaj.org/article/e7f656a6479e40eab7f4b02badb8c022
Meaningful benefit of disease‐modifying treatment: Evaluating changes in health‐related resource use
Autor:
Carolyn W. Zhu, Mary Sano
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Are reductions in the rate of decline from the new disease‐modifying treatments (DMTs) in early Alzheimer's disease (AD) meaningful? We examined whether such reductions may be reflected in changes in health‐related resource
Externí odkaz:
https://doaj.org/article/a64a442104d340fba1c9e1e6ef1fda75
Autor:
Giovanna Borriello, Clara Grazia Chisari, Davide Maimone, Massimiliano Mirabella, Damiano Paolicelli, Francesco Assogna, Sandro Caradonna, Francesco Patti
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Patient-reported outcomes (PROs) are essential for understanding the effects of MS and its treatments on patients’ lives; they play an important role in multiple sclerosis (MS) research and practice. We present the protocol for an observational stu
Externí odkaz:
https://doaj.org/article/47763cf7864043f7a8c30a5aa3fb3f51
Autor:
Мadina А. Omarova, Аleksey N. Boyko
Publikováno v:
Клиническая практика, Vol 14, Iss 4, Pp 88-93 (2024)
Over the past decade, the scientific research has shown that the community of microorganisms that inhabit the gut, known as the gut microbiota, is closely linked to human health and disease, in part as a result of its influence on the systemic immune
Externí odkaz:
https://doaj.org/article/f0cd252389e54d3b828f0b4108071845
Autor:
Yongjin Ahn, Sun-Jae Lee, Yong Suk Moon, Yoon-Jin Lee, Jung Hyun Park, Yongmin Chun, Dong Rak Kwon, Sang Chul Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9585 (2024)
Although frequently prescribed for frozen shoulder, it is not known if corticosteroid injections improve the course of frozen shoulder. This study aimed to assess the disease-modifying effects of an intra-articular corticosteroid administration at th
Externí odkaz:
https://doaj.org/article/dae3123dd5c14b6a83afcc858dba8186
Autor:
Massimo Filippi, Laura Ferrè, Chiara Zanetta, Caterina Rizzi, Gabriella Pessina, Francesco Assogna, Maria A. Rocca
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Disease-modifying therapies (DMTs) for multiple sclerosis (MS) reduce relapse frequency, magnetic resonance imaging (MRI) activity, and slow disability progression. Numerous DMTs are approved for relapsing forms of MS although real-world data on pati
Externí odkaz:
https://doaj.org/article/ef54c05740f2416b8afe67eb74d099e0
Autor:
Tim Spelman, Melinda Magyari, Helmut Butzkueven, Anneke Van Der Walt, Sandra Vukusic, Maria Trojano, Pietro Iaffaldano, Dana Horáková, Jirí Drahota, Fabio Pellegrini, Robert Hyde, Pierre Duquette, Jeannette Lechner-Scott, Seyed Aidin Sajedi, Patrice Lalive, Vahid Shaygannejad, Serkan Ozakbas, Sara Eichau, Raed Alroughani, Murat Terzi, Marc Girard, Tomas Kalincik, Francois Grand'Maison, Olga Skibina, Samia J. Khoury, Bassem Yamout, Maria Jose Sa, Oliver Gerlach, Yolanda Blanco, Rana Karabudak, Celia Oreja-Guevara, Ayse Altintas, Stella Hughes, Pamela McCombe, Radek Ampapa, Koen de Gans, Chris McGuigan, Aysun Soysal, Julie Prevost, Nevin John, Jihad Inshasi, Leszek Stawiarz, Ali Manouchehrinia, Lars Forsberg, Finn Sellebjerg, Anna Glaser, Luigi Pontieri, Hanna Joensen, Peter Vestergaard Rasmussen, Tobias Sejbaek, Mai Bang Poulsen, Jeppe Romme Christensen, Matthias Kant, Morten Stilund, Henrik Mathiesen, Jan Hillert, The Big MS Data Network: a collaboration of the Czech MS Registry, the Danish MS Registry, Italian MS Registry, Swedish MS Registry, MSBase Study Group, and OFSEP
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundTreatment switching is a common challenge and opportunity in real-world clinical practice. Increasing diversity in disease-modifying treatments (DMTs) has generated interest in the identification of reliable and robust predictors of treatme
Externí odkaz:
https://doaj.org/article/3d52ca1fdc794fa48cba7a9cc328885d
Autor:
Dorota Kujawa, Lukasz Laczmanski, Slawomir Budrewicz, Anna Pokryszko-Dragan, Maria Podbielska
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTMultiple sclerosis (MS) causes long-lasting, multifocal damage to the central nervous system. The complex background of MS is associated with autoimmune inflammation and neurodegeneration processes, and is potentially affected by many contrib
Externí odkaz:
https://doaj.org/article/5fa345507d8545bdbe1c2672657e13e2