Zobrazeno 1 - 10
of 2 104
pro vyhledávání: '"Disease mechanisms"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8031-8052 (2024)
Neuraminidases catalyze the desialylation of cell-surface glycoconjugates and play crucial roles in the development and function of tissues and organs. In both physiological and pathophysiological contexts, neuraminidases mediate diverse biological a
Externí odkaz:
https://doaj.org/article/28d55a6346104e9d8db600b3f020cea4
Autor:
Andrew R. Findlay
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/eff115f3ac0a4e4db2e5b92cb5c11ad4
Autor:
Ella J. Gehrke, Jacob Thompson, Emily Kalmanek, Sarah T. Stanley, Joseph Laird, Sajag Bhattarai, Brianna Lobeck, Sara Mayer, Angela Mahoney, Salma Hassan, Ying Hsu, Arlene Drack
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionX-linked retinoschisis (XLRS) is a vitreoretinal dystrophy caused by RS1 gene mutations which disrupt retinoschisin-1 (RS1) function. Vital for retinal architecture, the absence of functional RS1 leads to the development of intraretinal c
Externí odkaz:
https://doaj.org/article/97956e756020459d94d1cdf5dba195c3
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/f1839c52564b4545b4c39bc282eef3e1
Autor:
Ella J. Gehrke, Araniko Pandey, Jacob Thompson, Sajag Bhattarai, Prajwal Gurung, Ying Hsu, Arlene V. Drack
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
PurposePrevious studies have reported Caspase-1 (Casp1) is upregulated in mouse models of Juvenile X-linked Retinoschisis (XLRS), however no functional role for Casp1 in disease progression has been identified. We performed electroretinogram (ERG) an
Externí odkaz:
https://doaj.org/article/679fb165ad7c4d5093161d3b6add5eeb
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPrior research has indicated a link between psoriasis and the susceptibility to breast cancer (BC); however, a definitive causal relationship remains elusive. This study sought to elucidate the causal connection and shared underlying mechan
Externí odkaz:
https://doaj.org/article/ad76eb32ad7349878530970dd1f1e93a
Publikováno v:
Food Science and Human Wellness, Vol 12, Iss 5, Pp 1409-1426 (2023)
Food-microbiota-host interactions provide an overarching framework for understanding the function of the gut microbiota axis. Diet is a major modulator of gut microbiota. Plant-based foods are rich in phytochemicals; therefore, it is essential to ass
Externí odkaz:
https://doaj.org/article/a1cd8feaaba1422385d758b3e5701464
Autor:
Jiafeng Zou, Zeting Yuan, Xiaojie Chen, You Chen, Min Yao, Yang Chen, Xiang Li, Yi Chen, Wenxing Ding, Chuanhe Xia, Yuzheng Zhao, Feng Gao
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 1, Pp 100858- (2024)
Hydrogen sulfide (H2S) is a toxic, essential gas used in various biological and physical processes and has been the subject of many targeted studies on its role as a new gas transmitter. These studies have mainly focused on the production and pharmac
Externí odkaz:
https://doaj.org/article/ddb458fe18444b45beca674dafe3fc9c
Autor:
Sofia Marcolini, Jaime D. Mondragón, Esther E. Bron, Geert J. Biessels, Jurgen A.H.R. Claassen, Janne M. Papma, Huub Middelkoop, Rudi A.J.O. Dierckx, Ronald J.H. Borra, Inez H.G.B. Ramakers, Wiesje M. van der Flier, Natasha M. Maurits, Peter P. De Deyn
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100192- (2024)
Background: The role of small vessel disease in the development of dementia is not yet completely understood. Functional brain connectivity has been shown to differ between individuals with and without cerebral small vessel disease. However, a compre
Externí odkaz:
https://doaj.org/article/5596df6024c14dde8dea3f848664da20
Autor:
Alexandru Schiopu, Harry Björkbacka, Gayathri Narasimhan, Bi Juin Loong, Gunnar Engström, Olle Melander, Marju Orho-Melander, Jan Nilsson
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground There is an unmet clinical need for novel therapies addressing the residual risk in patients receiving guideline preventive therapy for coronary heart disease. Experimental studies have identified a pro-atherogenic role of the oxid
Externí odkaz:
https://doaj.org/article/66eb19c3bf4e4aecb9cafddfeec12b8b