Nf1 deficiency modulates the stromal environment in the pretumorigenic rat mammary gland.

Autor: Arumugam M; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States., Tovar EA; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States., Essenburg CJ; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States., Dischinger PS; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States., Beddows I; Biostatistics ad Bioinformatics Core, Van Andel Research Institute, Grand Rapids, MI, United States., Wolfrum E; Biostatistics ad Bioinformatics Core, Van Andel Research Institute, Grand Rapids, MI, United States., Madaj ZB; Biostatistics ad Bioinformatics Core, Van Andel Research Institute, Grand Rapids, MI, United States., Turner L; Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, MI, United States., Feenstra K; Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, MI, United States., Gallik KL; Optical Imaging Core, Van Andel Research Institute, Grand Rapids, MI, United States., Cohen L; Optical Imaging Core, Van Andel Research Institute, Grand Rapids, MI, United States., Nichols M; Flow Cytometry Core, Van Andel Research Institute, Grand Rapids, MI, United States., Sheridan RTC; Flow Cytometry Core, Van Andel Research Institute, Grand Rapids, MI, United States., Esquibel CR; Optical Imaging Core, Van Andel Research Institute, Grand Rapids, MI, United States., Mouneimne G; University of Arizona Cancer Center, Tucson, AZ, United States.; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, United States., Graveel CR; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States., Steensma MR; Department of Cell Biology, Van Andel Research Institute, Grand Rapids, MI, United States.; Helen DeVos Children's Hospital, Spectrum Health System, Grand Rapids, MI, United States.; Michigan State University College of Human Medicine, Grand Rapids, MI, United States.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2024 May 10; Vol. 12, pp. 1375441. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).

Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling.

Autor: Grit JL; Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. NE, Grand Rapids, MI, 49503, USA., Johnson BK; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Dischinger PS; Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. NE, Grand Rapids, MI, 49503, USA., J Essenburg C; Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. NE, Grand Rapids, MI, 49503, USA., Adams M; Genomics Core, Van Andel Research Institute, Grand Rapids, MI, USA., Campbell S; Helen DeVos Children's Hospital, Spectrum Health System, Grand Rapids, MI, USA., Pollard K; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pratilas CA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Triche TJ Jr; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Graveel CR; Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. NE, Grand Rapids, MI, 49503, USA., Steensma MR; Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. NE, Grand Rapids, MI, 49503, USA. Matt.Steensma@vai.org.; Helen DeVos Children's Hospital, Spectrum Health System, Grand Rapids, MI, USA. Matt.Steensma@vai.org.; Michigan State University College of Human Medicine, Grand Rapids, MI, USA. Matt.Steensma@vai.org.

Publikováno v: Epigenetics & chromatin [Epigenetics Chromatin] 2021 Jan 13; Vol. 14 (1), pp. 7. Date of Electronic Publication: 2021 Jan 13.

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer.

Autor: Dischinger PS; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Tovar EA; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Essenburg CJ; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Madaj ZB; 2Bioinformatics & Biostatistics Core, Van Andel Research Institute, Grand Rapids, MI USA., Gardner EE; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Callaghan ME; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Turner AN; 3Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL USA., Challa AK; 3Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL USA., Kempston T; 4Vivarium and Transgenics Core, Van Andel Research Institute, Grand Rapids, MI USA., Eagleson B; 4Vivarium and Transgenics Core, Van Andel Research Institute, Grand Rapids, MI USA., Kesterson RA; 3Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL USA., Bronson RT; 5Rodent Histopathology Core Dana Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA USA., Bowman MJ; 2Bioinformatics & Biostatistics Core, Van Andel Research Institute, Grand Rapids, MI USA., Graveel CR; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA., Steensma MR; 1Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI USA.; 6Helen DeVos Children's Hospital, Spectrum Health System, Grand Rapids, MI USA.; Michigan State University College of Human Medicine, Grand Rapids, MI USA.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2018 Aug 30; Vol. 4, pp. 29. Date of Electronic Publication: 2018 Aug 30 (Print Publication: 2018).