Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dirui Li"'
Autor:
Xuecheng Li, Yi Lu, Xiaoshuang Liang, Xiaofei Zhou, Dirui Li, Zan Zhang, Yunchao Niu, Shuaishuai Liu, Ling Ye, Rufeng Zhang
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286257 (2023)
Non-alcoholic fatty liver disease (NAFLD) has a high prevalence worldwide, with a significant proportion of patients progressing into non-alcoholic steatohepatitis (NASH) and further into cirrhosis and hepatocellular carcinoma (HCC). Most of the curr
Externí odkaz:
https://doaj.org/article/b55e76995d0c4a4f86e698326b78eb79
Publikováno v:
BioTechniques, Vol 52, Iss 3, Pp 173-176 (2012)
The nematode Caenorhabditis elegans is an important model animal for biological research. Currently, transgenic C. elegans strains are mainly generated by injecting DNA encoding a gene of interest, in combination with a reporter gene, into the gonad.
Externí odkaz:
https://doaj.org/article/31b595ae456e41c388a2b079543e6156
Publikováno v:
Cancer Research. 81:501-501
4-1BB is an activation-induced costimulatory TNF receptor family member which is expressed on a variety of cell types such as activated T cells, NK cells, DCs, B cells, monocytes and Neutrophils. 4-1BB/4-1BBL interaction leads to a series of activati
Publikováno v:
Cancer Research. 81:2942-2942
In recent years, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment. One of the potential therapeutic targets that seems increasingly attractive is LAG-3 (Lymphocyte activation gene 3, CD223), a human protein encoded by the LAG3
Publikováno v:
Cancer Research. 80:590-590
The development of bifunctional/multifunctional therapeutics have gained tremendous traction in recent years. Preclinical efficacy evaluation of bi-functional antibody drugs faces two main problems: first is the often limited cross-reaction between t
Publikováno v:
Cancer Research. 80:589-589
4-1BB (CD137) belongs to the TNFR superfamily and is expressed by activated CD4 helper T cells, B cells, natural killer cells, natural killer T cells, dendritic cells and Treg cells. 4-1BB is a potential therapeutic target as it enhances tumor reject
Publikováno v:
BioTechniques. 52(3)
The nematode Caenorhabditis elegans is an important model animal for biological research. Currently, transgenic C. elegans strains are mainly generated by injecting DNA encoding a gene of interest, in combination with a reporter gene, into the gonad.
Autor:
Jingjing Xie, Dirui Li, Shouping Zhang, Ming Wang, Jia Xue, Lun-Quan Sun, Jingmin Cui, Yanxin Hu, Jonathan P. Wong, Levon M. Khachigian, Guozhong Zhang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (12):2479-2488
The cytokine storm which is a great burden on humanity in highly pathogenic influenza virus infections requires activation of multiple signaling pathways. These pathways, such as MAPK and JNK, are important for viral replication and host inflammatory