Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dirk Voelkel"'
Autor:
Paolo Rossato, Enrica Federti, Alessandro Matte, Helmut Glantschnig, Fabio Canneva, Maria Schuster, Sogue Coulibaly, Gerald Schrenk, Dirk Voelkel, Michael Dockal, Barbara Plaimauer, Immacolata Andolfo, Achille Iolascon, Hanspeter Rottensteiner, Herbert Gritsch, Friedrich Scheiflinger, Werner Hoellriegl, Lucia De Franceschi
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
Sickle cell disease (SCD) is an inherited red blood cell disorder that occurs worldwide. Acute vaso-occlusive crisis is the main cause of hospitalization in patients with SCD. There is growing evidence that inflammatory vasculopathy plays a key role
Externí odkaz:
https://doaj.org/article/8c70e0b3cd1f416b96b51f9736f32503
Autor:
Alfred Weber, Andrea Engelmaier, Dirk Voelkel, Robert Pachlinger, Friedrich Scheiflinger, Paul E. Monahan, Hanspeter Rottensteiner
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 29-37 (2018)
The description of hyper-functional factor IX (FIX) Padua triggered the development of BAX 335, an AAV8-based hemophilia B gene therapy vector designed to compensate for low FIX protein expression levels by expressing the FIX Padua variant, thereby r
Externí odkaz:
https://doaj.org/article/fa9ae81b998a4cfb8406bb20995b7a98
Autor:
Patrice Douillard, Michael Freissmuth, Gerhard Antoine, Michael Thiele, Daniel Fleischanderl, Peter Matthiessen, Dirk Voelkel, Randolf J. Kerschbaumer, Friedrich Scheiflinger, Nicolas Sabarth
Publikováno v:
Antibodies, Vol 8, Iss 3, p 46 (2019)
Efficacy, safety, and manufacturability of therapeutic antibodies are influenced by their biopharmaceutical and biophysical properties. These properties can be optimized by library approaches or rationale protein design. Here, we employed a protein e
Externí odkaz:
https://doaj.org/article/d7479ca3ea79470ea66ca2f7611c9575
Autor:
Robert Pachlinger, Alfred Weber, Hanspeter Rottensteiner, Dirk Voelkel, Paul E. Monahan, Friedrich Scheiflinger, Andrea Engelmaier
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 29-37 (2018)
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 29-37 (2018)
The description of hyper-functional factor IX (FIX) Padua triggered the development of BAX 335, an AAV8-based hemophilia B gene therapy vector designed to compensate for low FIX protein expression levels by expressing the FIX Padua variant, thereby r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b4e7dcbce6d3b6db11dc97298e08a2
https://doi.org/10.1016/j.omtm.2018.05.004
https://doi.org/10.1016/j.omtm.2018.05.004
Autor:
Peter Goettig, Julia Hollerweger, Peter Scholz, Dirk Voelkel, Hans Brandstetter, Patrice Douillard, Nicolas Sabarth, Randolf Kerschbaumer, Friedrich Scheiflinger, Alexander Schinagl, Michael Thiele
Publikováno v:
Biochemistry. 57:1523-1532
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory and tumor-promoting cytokine that occurs in two redox-dependent immunologically distinct conformational isoforms. The disease-related structural isoform of MIF (oxMIF) can be specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc29482d441d76423d11bab395a40e0
https://doi.org/10.1021/acs.biochem.7b01156
https://doi.org/10.1021/acs.biochem.7b01156
Autor:
Daniel Fleischanderl, Randolf Kerschbaumer, Gerhard Antoine, Dirk Voelkel, Peter Matthiessen, Nicolas Sabarth, Friedrich Scheiflinger, Patrice Douillard, Michael Freissmuth, Michael Thiele
Publikováno v:
Antibodies
Volume 8
Issue 3
Antibodies, Vol 8, Iss 3, p 46 (2019)
Volume 8
Issue 3
Antibodies, Vol 8, Iss 3, p 46 (2019)
Efficacy, safety, and manufacturability of therapeutic antibodies are influenced by their biopharmaceutical and biophysical properties. These properties can be optimized by library approaches or rationale protein design. Here, we employed a protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58f3dbe83a16ee4043b1ac1da0e532d
Autor:
Dirk Voelkel, Terry Fetterhoff
Publikováno v:
Research-Technology Management. 49:14-18
OVERVIEW:In the increasingly competitive landscape, there is a growing demand for companies to be innovative. However, the concept of innovation is confounded by the central question of what makes a product innovative. If innovation is defined as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::586a89cb93b206745a4bee8f287611aa
https://doi.org/10.1080/08956308.2006.11657373
https://doi.org/10.1080/08956308.2006.11657373
Autor:
Dirk Voelkel, Friedrich Huisken, Yurii N Polivanov, Yu. L. Chuzavkov, Sergei N Orlov, Valery V Smirnov, J. Marquez
Publikováno v:
Quantum Electronics. 28:157-161
A description is given of a repetitively pulse source of narrow-band coherent radiation with continuous frequency tuning in the ranges 1.5–1.85 μm and 2.5–3.7 μm, and with energies per pulse up to 8 and 3 mJ, respectively. The source is based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af30a98110dcdcaeab6cb3e8e4a1e51
https://doi.org/10.1070/qe1998v028n02abeh001153
https://doi.org/10.1070/qe1998v028n02abeh001153
Autor:
Dirk Voelkel, J. Marquez, Sergei N Orlov, Valery V Smirnov, Friedrich Huisken, Yu. L. Chuzavkov, Yu. N. Polivanov
Publikováno v:
Applied Physics B: Lasers and Optics. 65:93-99
H2), methane (CH4), carbon dioxide (CO2), and nitrous oxide (N2O) in a cell under equilibrium conditions and cooled in free jet expansions. For methane at room temperature the detection limit was 2×1012 molecules per cm3 and quantum state, enabling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a88d64f748490ab65834226331ebac
https://doi.org/10.1007/s003400050255
https://doi.org/10.1007/s003400050255
Publikováno v:
Applied Physics B: Lasers and Optics. 64:699-705
fractional absorption) and generality of IR-CRLAS for combustion studies is demonstrated for low pressure laminar flames and is shown to be robust even in sooting environments with high temperature gradients. The ability to obtain (1-D) spatially res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93898dbd481bffd6c7cb786581b5ed8e
https://doi.org/10.1007/s003400050236
https://doi.org/10.1007/s003400050236