Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Dirk T. S. Rijkers"'
Autor:
Eefjan Breukink, Johan Kemmink, Rianne A. G. Harmsen, Dirk T. S. Rijkers, Nourdin Ghalit, Rob M. J. Liskamp
Publikováno v:
Tetrahedron. 70:7691-7699
The bacteria-specific membrane component lipid II is essential for bacterial cell wall synthesis. A tricyclic nisin mimic was designed and synthesized in which both thioether moieties were mimicked by an alkane-bridge, as well as the introduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af270147507fd3cf0941a2d806ec5ae5
https://doi.org/10.1016/j.tet.2014.06.023
https://doi.org/10.1016/j.tet.2014.06.023
Publikováno v:
Journal of Peptide Science. 19:692-699
Herein,wedescribeascalablepurificationofthelantibioticnisinviaanextraction/precipitationapproachusingabiphasicsystem,whichcanbecarriedoutupto40–80gramscale.Thisapproachresultsinanatleasttenfoldenrichmentofcommerciallyavailablepreparationsofnisin,w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::048d27e989a6493d8135ea98d85b8341
https://doi.org/10.1002/psc.2551
https://doi.org/10.1002/psc.2551
Autor:
Dirk T. S. Rijkers
Publikováno v:
Topics in Heterocyclic Chemistry ISBN: 9783319399393
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af4036ed6b78bc788a5131818e1865f7
https://doi.org/10.1007/7081_2016_203
https://doi.org/10.1007/7081_2016_203
Autor:
Albert J. de Graaf, Wim E. Hennink, Enrico Mastrobattista, Tina Vermonden, Cornelus F. van Nostrum, Rob M. J. Liskamp, Dirk T. S. Rijkers
Publikováno v:
Macromolecules. 45:842-851
Peptide-hybrid ABC block copolymers were synthesized by growing two different polymer chains from a native peptide using atom transfer radical polymerization (ATRP). To this end, two different ATRP initiators were coupled via orthogonal methods to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3bc1051f5eaed993477966a6834ffa
https://doi.org/10.1021/ma2024667
https://doi.org/10.1021/ma2024667
Publikováno v:
Tetrahedron Letters. 52:6963-6967
We report on the chemoselective coupling between colorless peptide fragments functionalized with a mutually reactive electron-rich Nα-(4-ethynylphenyl)-Nα-(methyl)-glycyl- and an electron-deficient [4-(2,2-dicyanovinyl)]benzoyl moiety. The resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69bd56ee29ba30d9000dd51534d1252
https://doi.org/10.1016/j.tetlet.2011.10.084
https://doi.org/10.1016/j.tetlet.2011.10.084
Autor:
J. Antoinette Killian, Bianca Y. van Duyl, Dirk T. S. Rijkers, Thomas K.M. Nyholm, Rob M. J. Liskamp
Publikováno v:
Biophysical Journal. 101(8):1959-1967
The aim of this study was to gain insight into how interactions between proteins and lipids in membranes are sensed at the protein-lipid interface. As a probe to analyze this interface, we used deuterium-labeled acyl chains that were covalently linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e34a1ae2da13dc2f67d36a214b0b4c1
Autor:
Peter J. L. M. Quaedflieg, Timo Nuijens, Dirk T. S. Rijkers, John A. W. Kruijtzer, Rob M. J. Liskamp, Claudia Cusan, Annette C.H.M. Schepers
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 71:79-84
Chemoenzymatic peptide synthesis is potentially the most cost-efficient technology for the synthesis of short and medium-sized peptides. However, there are still some limitations when challenging peptides, e.g. containing sterically demanding acyl do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d87bdb131455c1c4e0bbc4b03547d5
https://doi.org/10.1016/j.molcatb.2011.03.012
https://doi.org/10.1016/j.molcatb.2011.03.012
Autor:
Dirk T. S. Rijkers, François Diederich
Publikováno v:
Tetrahedron Letters. 52:4021-4025
Herein, we report a novel approach for the synthesis of π-conjugated peptide-based donor–acceptor (D-π-A) chromophores, by reacting electron-rich alkynes with tetracyanoethylene. The desired tetracyanobutadiene-scaffolded peptides were obtained i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7025d2b77002060efbc14e1d757ab2
https://doi.org/10.1016/j.tetlet.2011.05.136
https://doi.org/10.1016/j.tetlet.2011.05.136
Publikováno v:
ChemBioChem. 12:1626-1653
Despite their enormous diversity in biological function and structure, peptides and proteins are endowed with properties that have induced and stimulated the development of peptidomimetics. Clearly, peptides can be considered as the "stem" of a phylo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d3c0ffc921d4dae67a42378c8a5dc5
https://doi.org/10.1002/cbic.201000717
https://doi.org/10.1002/cbic.201000717
Autor:
Elena Piva, Dirk T. S. Rijkers, Timo Nuijens, Peter J. L. M. Quaedflieg, Rob M. J. Liskamp, John A. W. Kruijtzer
Publikováno v:
Advanced Synthesis & Catalysis. 353:1039-1044
Chemoenzymatic peptide synthesis is potentially the most cost-efficient technology for the synthesis of short and medium-sized peptides with some important advantages. For instance, stoichiometric amounts of expensive coupling reagents are not requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295ec1a008698b6903a8b3ccab8c4302
https://doi.org/10.1002/adsc.201000943
https://doi.org/10.1002/adsc.201000943