Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dirk Smith"'
Autor:
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
There is an unmet need in severe asthma where approximately 40% of patients exhibit poor β-agonist responsiveness, suffer daily symptoms and show frequent exacerbations. Antagonists of the Ca2+-activated Cl− channel, TMEM16A, offers a new mechanis
Externí odkaz:
https://doaj.org/article/41d8cbf66f0741758aee1902a2f9ab21
Autor:
Dirk Smith, Hannes Helgason, Patrick Sulem, Unnur Steina Bjornsdottir, Ai Ching Lim, Gardar Sveinbjornsson, Haruki Hasegawa, Michael Brown, Randal R Ketchem, Monica Gavala, Logan Garrett, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Asgeir Sigurdsson, Olafur T Magnusson, Gudmundur I Eyjolfsson, Isleifur Olafsson, Pall Torfi Onundarson, Olof Sigurdardottir, David Gislason, Thorarinn Gislason, Bjorn Runar Ludviksson, Dora Ludviksdottir, H Marike Boezen, Andrea Heinzmann, Marcus Krueger, Celeste Porsbjerg, Tarunveer S Ahluwalia, Johannes Waage, Vibeke Backer, Klaus A Deichmann, Gerard H Koppelman, Klaus Bønnelykke, Hans Bisgaard, Gisli Masson, Unnur Thorsteinsdottir, Daniel F Gudbjartsson, James A Johnston, Ingileif Jonsdottir, Kari Stefansson
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006659 (2017)
IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic disease. Common variants at IL33 and IL1RL1, encoding the IL-33 receptor ST2, associate wit
Externí odkaz:
https://doaj.org/article/e16a276b317c4e85bf2f763ea930be81
Autor:
Don D. Sin, Matthew J. Gold, Tracee Wee, Christopher Carlsten, Jeremy A. Hirota, Dirk Smith, Stephan VanEeden, Phil Hansbro, Paul Hiebert, Leigh G Parkinson, Kelly M. McNagny, Darryl A. Knight
Publikováno v:
American journal of respiratory cell and molecular biology. 52(1)
Exposure to particulate matter (PM), a major component of air pollution, contributes to increased morbidity and mortality worldwide. Inhaled PM induces innate immune responses by airway epithelial cells that may lead to the exacerbation or de novo de
Publikováno v:
Journal of Plant Registrations. 1:49-50
Autor:
Charles, Dinarello, William, Arend, John, Sims, Dirk, Smith, Hal, Blumberg, Luke, O'Neill, Raphaela, Goldbach-Mansky, Theresa, Pizarro, H, Hoffman, Philip, Bufler, Marcel, Nold, Pietro, Ghezzi, Alberto, Mantovani, Cecilia, Garlanda, Diana, Boraschi, Anna, Rubartelli, Mihai, Netea, Jos, van der Meer, Leo, Joosten, Tom, Mandrup-Poulsen, Marc, Donath, Eli, Lewis, Josef, Pfeilschifter, Michael, Martin, Michael, Kracht, H, Muehl, Daniela, Novick, Miodrag, Lukic, Bruno, Conti, Alan, Solinger, Peyman, Kelk, Kelk, Peyman, Frank, van de Veerdonk, Chiristopher, Gabel
Publikováno v:
Nature Immunology, 11, 11, pp. 973-973
Nature Immunology, 11, 973-973
Nature Immunology, 11, 973-973
To the Editor: Newly cloned interleukin 1 (IL-1) family members1–3 were originally given an IL-1 family (IL-1F) designation4, but as functions have now been elucidated for several of these5,6, we propose that each now be assigned an individual inte
Conference
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Conference
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