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Autor:
Eric J. White, Sergey V. Fridrikh, Ekaterina Protozanova, Dirk Peter Ten Broeck, Douglas B. Cameron, Rudolf Gilmanshin, Emilia Mollova, Meng Zhang
Publikováno v:
Analytical Biochemistry. 402:83-90
Here we describe bacterial genotyping by direct linear analysis (DLA) single-molecule mapping. DLA involves preparation of restriction digest of genomic DNA labeled with a sequence-specific fluorescent probe and stained nonspecifically with intercala