Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dirk O. Bauerschlag"'
Autor:
Christoph Rogmans, Jan Dittrich, Emily Hamm, Jörg Paul Weimer, David Holthaus, Norbert Arnold, Inken Flörkemeier, Nicolai Maass, Peer Jansen, Astrid Dempfle, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Acquired or de novo resistance to poly (ADP-ribose) polymerase inhibitors (PARPi) is a major challenge to ovarian cancer treatment. Therefore, strategies to overcome PARPi resistance are critical to improve prognosis. The purpose of this stu
Externí odkaz:
https://doaj.org/article/4291c4464e794268896575de7315d9cc
Autor:
Inken Flörkemeier, Lisa K. Antons, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, Sandra Krüger, Regina Scherließ, Astrid Dempfle, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract In vitro, spheroid models have become well established in cancer research because they can better mimic certain characteristics of in vivo tumours. However, interaction with the tumour microenvironment, such as cancer-associated fibroblasts,
Externí odkaz:
https://doaj.org/article/64babe67f1b14d97a499efdf4b30fa15
Inhibition of ADAM17 increases the cytotoxic effect of cisplatin in cervical spheroids and organoids
Autor:
David Holthaus, Christoph Rogmans, Ina Gursinski, Alvaro Quevedo-Olmos, Marzieh Ehsani, Mandy Mangler, Inken Flörkemeier, Jörg P. Weimer, Thomas F. Meyer, Nicolai Maass, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionCervical cancer represents one of the main causes of female, cancer-related mortality worldwide. The majority of cancers are caused by human papillomaviruses such as HPV16 and HPV18. As chemotherapeutic resistance to first-line platinum t
Externí odkaz:
https://doaj.org/article/03b213b6b8984864bcfc1799a85cfa7e
Autor:
Amelie Limburg, Xueqian Qian, Bernice Brechtefeld, Nina Hedemann, Inken Flörkemeier, Christoph Rogmans, Leticia Oliveira-Ferrer, Nicolai Maass, Norbert Arnold, Dirk O. Bauerschlag, Jörg Paul Weimer
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1171 (2024)
Examinations of ovarian cancer cells require the ability to identify tumor cells. Array-based comparative genome hybridization (aCGH) on 30 ovarian carcinomas (OC) identified three genomic loci (8q24.23; 17p12; 18q22.3) over- or under-represented in
Externí odkaz:
https://doaj.org/article/8d8eff3e1e8741f2b322bb36731c4e4b
Autor:
Inken Flörkemeier, Tamara N. Steinhauer, Nina Hedemann, Magnus Ölander, Per Artursson, Bernd Clement, Dirk O. Bauerschlag
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Ovarian cancer (OvCa) constitutes a rare and highly aggressive malignancy and is one of the most lethal of all gynaecologic neoplasms. Due to chemotherapy resistance and treatment limitations because of side effects, OvCa is still not suf
Externí odkaz:
https://doaj.org/article/8b89334405764c299bc1e0e335c0f7dc
Autor:
Matthias Peipp, Martin Gramatzki, Bernd Clement, Dirk O. Bauerschlag, Andreas Günther, Inken Floerkemeier, Hauke Wilcken, Steffen Krohn, Carina Lynn Gehlert, Christian Kellner, Katja Klausz
Supplementary Figures 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dbe22b0e070924be809f33addf7faa
https://doi.org/10.1158/1535-7163.22522354
https://doi.org/10.1158/1535-7163.22522354
Autor:
Matthias Peipp, Martin Gramatzki, Bernd Clement, Dirk O. Bauerschlag, Andreas Günther, Inken Floerkemeier, Hauke Wilcken, Steffen Krohn, Carina Lynn Gehlert, Christian Kellner, Katja Klausz
P8-D6 is a novel dual inhibitor of human topoisomerase I (TOP1) and II (TOP2) with broad pro-apoptotic antitumor activity. NCI-60 screening revealed markedly improved cytotoxicity of P8-D6 against solid and leukemia cell lines compared with other sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da6d0e8e73b4e09348a7b5d8e131497
https://doi.org/10.1158/1535-7163.c.6543349.v1
https://doi.org/10.1158/1535-7163.c.6543349.v1
Autor:
Kathrin Hartwig, Dirk O. Bauerschlag
Publikováno v:
InFo Hämatologie + Onkologie. 26:30-31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79331b8b5218b01939aa3aadd32dc764
https://doi.org/10.1007/s15004-023-9889-x
https://doi.org/10.1007/s15004-023-9889-x
Autor:
Maja Grohe, Dirk O. Bauerschlag
Publikováno v:
InFo Hämatologie + Onkologie. 26:24-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47e880f581878195c48bc40ef7e81dd0
https://doi.org/10.1007/s15004-023-9855-7
https://doi.org/10.1007/s15004-023-9855-7
Autor:
Christoph Rogmans, Julia Feuerborn, Leonie Treeck, Nils Tribian, Inken Flörkemeier, Norbert Arnold, Jörg Paul Weimer, Nicolai Maass, Peer Jansen, Wolfgang Lieb, Astrid Dempfle, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Cancers; Volume 14; Issue 23; Pages: 5867
Ovarian cancer is the third most common gynecological malignancy and has the highest mortality rate. Owing to unspecific symptoms, ovarian cancer is not detected until an advanced stage in about two-thirds of cases. Therefore, it is crucial to establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83880a01e1d4e21588644d6c500def38
https://pubmed.ncbi.nlm.nih.gov/36497350
https://pubmed.ncbi.nlm.nih.gov/36497350